3D skin imaging for Kaposi sarcoma care

PRecision IMaging to Evaluate Kaposi Sarcoma (PRIME-KS)

NIH-funded research Washington University · NIH-11400582

This project will use a portable 3D imaging device with AI to measure Kaposi sarcoma skin lesions more accurately for people receiving treatment in East Africa.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionWashington University NIH-funded
Lab location1 site (Saint Louis, United States)
Project IDNIH-11400582 on NIH RePORTER

What this research studies

You would have your skin lesions photographed with a small, handheld SkinScan3D device that creates high-resolution 3D pictures showing lesion height and volume. The images are processed by AI to give objective, repeatable measurements instead of relying only on visual estimates. Clinicians, nurses, and patients will help refine how the device is used in routine clinic visits so it fits busy care settings. The goal is to integrate the device into local workflows at participating clinics in East Africa.

Who could benefit from this research

Good fit: Ideal participants are people with visible Kaposi sarcoma skin lesions who receive care at participating clinics in Malawi, Mozambique, Uganda, or Kenya.

Not a fit: People who have only internal (visceral) Kaposi sarcoma, no visible skin lesions, or who cannot attend participating clinics are unlikely to receive direct benefit from this imaging approach.

Why it matters

Potential benefit: If successful, this could provide faster, more objective measurements of KS lesions to guide treatment decisions and reduce unnecessary chemotherapy exposure.

How similar studies have performed: AI and 3D imaging approaches have shown promise in dermatology for lesion measurement, but using a portable liquid-lens 3D system specifically for Kaposi sarcoma in East Africa is novel and not yet tested at scale.

Where this research is happening

Saint Louis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.