Condition

Erectile Dysfunction clinical trials and research

• 36Clinical trials
• 8NIH research projects
• 1New in 30 days
• 14Countries

Newest Erectile Dysfunction clinical trials

All recruiting trials (36)

• HIP2602 for Erectile Dysfunction: Testing a new treatment in adults

  This study tests whether HIP2602, alone or with related formulations, can improve erectile function in adult men with long-standing erectile dysfunction who partner with the same adult female partner.

  Recruiting Phase 3 Hanmi Pharmaceutical Company Limited · Busan · NCT07899073

• Platelet-Rich Plasma for Erectile Dysfunction After Prostate Surgery

  This trial tests whether injecting a patient’s own platelet-rich plasma can improve erectile function in men who have persistent ED more than a year after nerve-sparing radical prostatectomy.

  Recruiting Herlev and Gentofte Hospital · Herlev · NCT07863388

• Pudendal artery plaque and erectile dysfunction in men with heart disease

  A small study tests whether plaque in the internal pudendal arteries is linked to erectile function in men with coronary artery disease who are undergoing coronary angiography.

  Recruiting Hospital Central Militar · Mexico City, Mexico City · NCT07856199

• Piezoelectric Low-Intensity Shockwave Therapy for erectile dysfunction in PDE5i nonresponders

  This study tests whether four weeks of low‑intensity, linear piezoelectric shockwave therapy can improve erectile function in men with ED who did not respond to PDE5 inhibitors.

  Recruiting The University of Hong Kong · Hong Kong · NCT07820748

• Sexual function and quality of life in monogamous vs polygamous marriages among Egyptian men

  This is a web-based survey to see if marital structure affects erectile function and sexual quality of life in Egyptian men who are married.

  Recruiting Al-Azhar University · Cairo · NCT07783958

• Lifestyle changes to improve erectile function in men with metabolic syndrome

  A six-month lifestyle program is being tried to see if it improves erectile function and penile blood flow in men who have erectile dysfunction linked to metabolic syndrome.

  Recruiting at 2 sites Al-Azhar University · Cairo and 1 other locations · NCT07758842

• Daily tadalafil added to PDE5 inhibitor therapy for men with resistant erectile dysfunction

  This study tests whether adding a daily 5 mg tadalafil to a person's usual on-demand PDE5 inhibitor helps men with resistant erectile dysfunction perform better than using tadalafil alone.

  Recruiting Phase 4 Al-Azhar University · Cairo · NCT07753720

• Rehabilitation and Sex Therapy to Improve Recovery After Prostate Cancer Treatment

  This study tests whether adding telehealth sex therapy to pelvic floor physical therapy helps men recover sexual function after prostate cancer treatment.

  Recruiting Duke University · Durham, North Carolina · NCT07685249

• L-Citrulline and Tadalafil for Mild to Moderate Erectile Dysfunction

  This study tests whether L-citrulline, tadalafil, or both together can improve erectile function in men with mild to moderate erectile dysfunction over 12 weeks.

  Recruiting Phase 4 Beni-Suef University · Banī Suwayf, Beni Suweif Governorate · NCT07642505

• LI-SWT for Erectile Dysfunction: A single-arm study at UCSF

  This study tests whether light intensity shockwave therapy can help men with erectile dysfunction and aims to see which patients are likely to benefit.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07592533

• Exercise for erectile dysfunction and premature ejaculation

  This project tests whether an 8-week, three-times-weekly exercise program helps men aged 25–45 who have erectile dysfunction and premature ejaculation.

  Recruiting Uskudar University · Istanbul · NCT07442396

• Long-term safety follow-up of Cellgram-ED for erectile dysfunction after prostate removal

  This follow-up will see if Cellgram-ED—your own bone marrow stem cells given into the penis—remains safe over several years for men with erectile dysfunction after radical prostatectomy.

  Recruiting at 4 sites Pharmicell Co., Ltd. · Seoul and 3 other locations · NCT07431008

• Adding exercise to vitamin D treatment for diabetic men with erectile dysfunction and low vitamin D.

  This trial will see if adding regular moderate treadmill walking to high‑dose vitamin D replacement helps men with type 2 diabetes, chronic erectile dysfunction, and low vitamin D levels.

  Recruiting Cairo University · Dokki, Giza Governorate · NCT07366970

• YN001 for ASCVD/Cerebrovascular Disease with Erectile Dysfunction

  A randomized, blinded study tests whether YN001 helps men with atherosclerotic cardiovascular disease and erectile dysfunction better than a placebo.

  Recruiting Phase 2 Beijing Inno Medicine Co., Ltd. · Beijing, Jilin · NCT07311330

• Penile lengthening with RestoreX before inflatable penile prosthesis surgery

  This test tries whether using the RestoreX penile traction device for several weeks before inflatable penile prosthesis surgery helps men with erectile dysfunction get a longer implant.

  Recruiting University of Pittsburgh · Pittsburgh, Pennsylvania · NCT07053826

• Stem cells to help erectile function after prostate surgery

  This phase 1/2 study tests whether injected stem cells can help men recover erectile function after radical prostatectomy for localized prostate cancer, compared to placebo.

  Recruiting Phase 1/2 The Methodist Hospital Research Institute · Houston, Texas · NCT07048314

• Lifestyle changes and CPAP for men with sleep apnea and metabolic issues

  This study is testing if combining lifestyle changes like diet and exercise with CPAP therapy can help men with sleep apnea and metabolic issues feel better.

  Recruiting Cairo University · Giza, Dokki · NCT06960746

• Nerve-sparing prostate surgery using micro-ultrasound guidance

  This study is testing a new approach to prostate surgery that uses advanced ultrasound technology to help men with localized prostate cancer keep their sexual function while effectively removing the cancer.

  Recruiting Phase 3 Icahn School of Medicine at Mount Sinai · New York, New York · NCT06945315

• Evaluating the effect of food on Hezkue Turbo® (sildenafil) in healthy men

  This study is testing how eating food affects the way healthy men absorb and respond to a new version of sildenafil, while also checking if the medication is safe to use.

  Recruiting Phase 1 Aspargo Labs, Inc · New York, New York · NCT06872866

• Exercise and its effects on sexual dysfunction in men with irritable bowel syndrome

  This study tests if regular elliptical exercise can help men with irritable bowel syndrome improve their sexual function and overall symptoms.

  Recruiting Cairo University · Dokki, Giza Governorate · NCT06783894

• EndoPAT to measure blood vessel health in men with erectile dysfunction and hypogonadism

  This project will test whether EndoPAT can detect changes in blood-vessel function in men with vasculogenic ED or hypogonadism before and 3–6 months after starting daily low-dose PDE5 inhibitors or testosterone therapy.

  Recruiting University of California, Irvine · Newport Beach, California · NCT06720597

• Lifestyle changes for obese men with sexual dysfunction and tinnitus

  This study is testing if a low-calorie diet combined with regular walking can help obese men with both sexual problems and ringing in their ears feel better.

  Recruiting Cairo University · Dokki, Giza Governorate · NCT06716125

• Injections of stem cells from fat tissue to treat erectile dysfunction

  This study is testing if injections of stem cells from fat can help men aged 30 to 75 with erectile dysfunction who haven't found relief from other treatments.

  Recruiting Jumeirah American Clinic · Dubai, Dubai · NCT06605508

• Nerve grafting technique to help preserve erectile function after prostate surgery

  This study is testing a new nerve grafting technique during prostate surgery to see if it can help men keep their erectile function after the operation.

  Recruiting at 2 sites Sir Mortimer B. Davis - Jewish General Hospital · Montreal, Quebec and 1 other locations · NCT06521710

• Pelvic floor therapy for erectile dysfunction and premature ejaculation

  This study is testing if pelvic floor therapy can help men with erectile dysfunction and premature ejaculation feel better after 12 weeks of treatment.

  Recruiting Boston Medical Group · Bogotá, Cundinamarca · NCT06425211

• Evaluating scrotal drainage during penile prosthesis surgery

  This study is testing if using a drainage tube during penile prosthesis surgery can help prevent complications without raising the risk of infections for patients.

  Recruiting A.O.U. Città della Salute e della Scienza · Torino, Torino and 1 other locations · NCT06147791

• Using shockwave therapy with Xiaflex to treat Peyronie's disease

  This study is testing if combining shockwave therapy with a medication called Xiaflex can help men with Peyronie's disease improve their penile curvature better than standard treatment alone.

  Recruiting Mayo Clinic · Rochester, Minnesota · NCT06065436

• Using Tadalafil to Improve Urinary and Sexual Function After Prostate Surgery

  This study is testing if Tadalafil can help men over 40 improve their urinary and sexual function after having prostate surgery for an enlarged prostate.

  Recruiting Phase 2/3 Mansoura University · Al Mansurah, Dakahlia Governorate · NCT05955001

• Comparing low-intensity shockwave and radial wave treatments for erectile dysfunction and pelvic pain

  This study is testing whether focused shockwave therapy or radial wave therapy can help men with erectile dysfunction and people with chronic pelvic pain feel better.

  Recruiting The Cleveland Clinic · Cleveland, Ohio · NCT05868668

• Evaluation of a new inflatable penile prosthesis for erectile dysfunction

  This study is testing a new inflatable penile implant to see if it safely helps men with erectile dysfunction feel better over the long term.

  Recruiting at 7 sites Rigicon, Inc. · Auchenflower and 6 other locations · NCT05574868

• Prostate stimulation to improve sexual function in men

  This study is testing a special device that stimulates the prostate to see if it can help men with sexual dysfunction feel better and improve their sexual performance.

  Recruiting Stanford University · Stanford, California · NCT05468931

• Wearable device for erectile dysfunction

  This study is testing a new wearable device to help men with erectile dysfunction have better sexual experiences without using medication.

  Recruiting Stanford University · Stanford, California · NCT05451563

• Testing a 3D-printed device for erectile dysfunction

  This study is testing a new 3D-printed device to see if it can help men with erectile dysfunction have better sexual experiences.

  Recruiting Stanford University · Stanford, California · NCT04624126

• Evaluating outcomes of a new penile implant for transgender men after surgery

  This study is testing a new penile implant designed for transgender men to see if it can help improve erectile function after surgery.

  Recruiting University Hospital, Ghent · Ghent, Oost-Vlaanderen · NCT04064671

• Implanting a penile prosthesis for erectile dysfunction

  This study tests whether an inflatable penile prosthesis can help men with erectile dysfunction who haven't found relief with other treatments feel more satisfied with their sexual performance.

  Recruiting Tanta University · Cairo, Elgharbia · NCT03466619

• Helping men recover sexual function after prostate cancer surgery

  This study tests two different ways to help men regain their sexual function after prostate cancer surgery to see which one works better.

  Recruiting Memorial Sloan Kettering Cancer Center · New York, New York · NCT02706561

NIH-funded research (8)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Why pelvic surgery can cause both bladder problems and erectile dysfunction

  Researchers are looking at whether inflammation of pelvic nerve ganglia after prostate or other pelvic surgery causes both bladder problems and erectile dysfunction in men.

  NIH research Albert Einstein College of Medicine · Bronx, United States · NIH-11309130

• Predicting heart disease risk in young male veterans with erectile dysfunction

  This project uses genetic risk scores and medical records to find which young male veterans with erectile dysfunction are most likely to have future heart problems.

  NIH research VA San Diego Healthcare System · San Diego, United States · NIH-11206878

• Topical sildenafil-nanoparticle for erectile dysfunction in adults with diabetes

  A science team is testing a new cream-like sildenafil formulation applied to the skin to help with erectile dysfunction, especially in adults with diabetes.

  NIH research Atticus Pharma INC · Greenville, United States · NIH-11186191

• Understanding how diabetes affects erectile function

  This research explores how certain cell signals contribute to erectile dysfunction in people with diabetes.

  NIH research University of South Carolina at Columbia · Columbia, United States · NIH-11091523

• Targeted Nanoparticle Therapy for Erectile Dysfunction

  This research explores a new way to deliver a healing molecule using tiny particles to help men with erectile dysfunction.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11083687

• Inflammation in pelvic nerves affecting bladder and erectile function after surgery

  This study is looking at how inflammation in the pelvic area after surgery, like prostate removal, might cause problems with bladder control and erections, and it hopes to find ways to help prevent these issues for patients.

  NIH research Albert Einstein College of Medicine · Bronx, United States · NIH-11073021

• Exploring the use of erectile dysfunction drugs to improve bone health in elderly females

  This study is looking at whether common erectile dysfunction medications, like tadalafil and vardenafil, can help improve bone health and prevent osteoporosis in older women by boosting bone growth.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11054645

• Understanding cardiovascular disease risk in young male veterans with erectile dysfunction

  This study is looking at how erectile dysfunction in young male veterans might be connected to heart problems, so we can find out which veterans need extra care and support for their heart health.

  NIH research VA San Diego Healthcare System · San Diego, United States · NIH-10925721

Related topics

Quick answers

How many Erectile Dysfunction clinical trials are recruiting right now?

36, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 14 countries. The most sites are in United States (13 trials), Egypt (10 trials), South Korea (2 trials), Colombia (1 trial), Australia (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 2, Phase 4: 2, Phase 2/3: 1, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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