Adding exercise to vitamin D treatment for diabetic men with erectile dysfunction and low vitamin D.
Is There a Benefit From Addition of Exercise in Diabetic Patients With ED Who Complain Low Vitamin D?
This trial will see if adding regular moderate treadmill walking to high‑dose vitamin D replacement helps men with type 2 diabetes, chronic erectile dysfunction, and low vitamin D levels.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Ages | 35 Years to 45 Years |
| Sex | Male |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Dokki, Giza Governorate) |
| Trial ID | NCT07366970 on ClinicalTrials.gov |
What this trial studies
Forty men with type 2 diabetes, chronic erectile dysfunction (>24 months), and documented vitamin D deficiency will be divided into two groups. Both groups will receive cholecalciferol 200,000 IU every two weeks for 12 weeks, while one group will also do supervised treadmill walking for one hour at moderate intensity three times per week for 12 weeks. Participants with cardiac, respiratory, renal, or liver disease are excluded. The study will track changes in erectile function and vitamin D status over the 12‑week period to compare the added effect of exercise versus vitamin D alone.
Who should consider this trial
Good fit: Ideal candidates are men with type 2 diabetes who have chronic erectile dysfunction for more than 24 months, documented low vitamin D, and who can safely perform moderate exercise without major cardiopulmonary, renal, or liver disease.
Not a fit: Patients with severe heart, lung, kidney, or liver disease, those whose ED is due to non‑modifiable structural or neurological causes, or those unable to exercise are less likely to benefit from the exercise component.
Why it matters
Potential benefit: If successful, adding regular moderate exercise to vitamin D replacement could improve erectile function and overall health beyond vitamin D alone.
How similar studies have performed: Previous studies show exercise and vitamin D supplementation can each improve metabolic health and some risk factors for sexual dysfunction, but combining supervised exercise with high‑dose vitamin D in diabetic ED is not well studied.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * diabetic men (forty) * type 2 diabetes * complaint of erectile dysfucntion (chronic complaint more than 24 months) * men with low vitamin D (deiciency in vitamin D) Exclusion Criteria: * cardiac patients * respiratory disease patients * renal disease * liver disease
Where this trial is running
Dokki, Giza Governorate
- Cairo University — Dokki, Giza Governorate, Egypt (Recruiting)
Study contacts
- Principal investigator: Ali MA Ismail, lecturer — Cairo University
- Study coordinator: Ali MA Ismail, lecturer
- Email: ali.mohamed@pt.cu.edu.eg
- Phone: 01005154209
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.