Clinical trial Recruiting at 1 site Interventional Ages 35 to 45 Men only

Adding exercise to vitamin D treatment for diabetic men with erectile dysfunction and low vitamin D.

Official title: Is There a Benefit From Addition of Exercise in Diabetic Patients With ED Who Complain Low Vitamin D?

Run by Cairo University · NCT07366970 · Data updated 2026-11-12

This trial will see if adding regular moderate treadmill walking to high‑dose vitamin D replacement helps men with type 2 diabetes, chronic erectile dysfunction, and low vitamin D levels.

Quick facts

Study typeInterventional
Ages35 Years to 45 Years
SexMen only
Enrollment40 (estimated)
SponsorCairo University
Academic / other
Locations1 site (Dokki, Giza Governorate)
StatusRecruiting
StartedDecember 5, 2025
Main results expectedMay 5, 2026
Study endsMay 5, 2026
Registry record updatedJanuary 26, 2026
Trial IDNCT07366970 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are men with type 2 diabetes who have chronic erectile dysfunction for more than 24 months, documented low vitamin D, and who can safely perform moderate exercise without major cardiopulmonary, renal, or liver disease.

Probably not a fit

Patients with severe heart, lung, kidney, or liver disease, those whose ED is due to non‑modifiable structural or neurological causes, or those unable to exercise are less likely to benefit from the exercise component.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Forty men with type 2 diabetes, chronic erectile dysfunction (>24 months), and documented vitamin D deficiency will be divided into two groups. Both groups will receive cholecalciferol 200,000 IU every two weeks for 12 weeks, while one group will also do supervised treadmill walking for one hour at moderate intensity three times per week for 12 weeks. Participants with cardiac, respiratory, renal, or liver disease are excluded. The study will track changes in erectile function and vitamin D status over the 12‑week period to compare the added effect of exercise versus vitamin D alone.

Why it matters

Potential benefit: If successful, adding regular moderate exercise to vitamin D replacement could improve erectile function and overall health beyond vitamin D alone.

How similar studies have gone: Previous studies show exercise and vitamin D supplementation can each improve metabolic health and some risk factors for sexual dysfunction, but combining supervised exercise with high‑dose vitamin D in diabetic ED is not well studied.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* diabetic men (forty)
* type 2 diabetes
* complaint of erectile dysfucntion (chronic complaint more than 24 months)
* men with low vitamin D (deiciency in vitamin D)

Exclusion Criteria:

* cardiac patients
* respiratory disease patients
* renal disease
* liver disease

Where it's running

  • Cairo University
    Dokki, Giza Governorate, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.