Condition

Atherosclerotic Cardiovascular Disease (ASCVD) clinical trials and research

• 10Clinical trials
• 30Countries

Newest Atherosclerotic Cardiovascular Disease (ASCVD) clinical trials

All recruiting trials (10)

• Understanding why some people see bigger LDL drops after starting ezetimibe

  This study tests what factors predict how much a person’s LDL cholesterol drops after starting ezetimibe, to help tailor cholesterol treatment.

  Recruiting Phase 4 Universidade do Porto · Porto · NCT07839741

• Health for Hungary: Long-term blood and health data collection to study aging and disease onset

  This study tests whether routine blood tests plus advanced molecular analyses can help detect the early stages of non-communicable diseases in adults over 40.

  Recruiting at 21 sites Center for Molecular Fingerprinting Research Nonprofit LLC · Balatonfüred and 32 other locations · NCT07743021

• Dual PCSK9 Inhibition in secondary prevention for high LDL-C with statin intolerance

  This study tests whether combining inclisiran and alirocumab lowers LDL cholesterol better than either drug alone in people with ASCVD who can’t tolerate statins.

  Recruiting Phase 4 University Medical Centre Ljubljana · Ljubljana · NCT07581808

• Comparing 50 mg and 100 mg daily aspirin for older adults with cardiovascular disease

  This tests whether taking 50 mg of aspirin daily works as well as 100 mg but causes fewer bleeding problems in Chinese people aged 60 and older with prior heart or blood vessel disease.

  Recruiting Peking University First Hospital · Beijing · NCT07542860

• Coronary calcium and high-sensitivity troponin testing in people with rheumatoid arthritis

  This study will test whether measuring coronary artery calcium and high-sensitivity troponin can find people with rheumatoid arthritis who should start cholesterol-lowering treatment even if general risk calculators don't recommend it.

  Recruiting at 3 sites Brigham and Women's Hospital · Boston, Massachusetts and 2 other locations · NCT07315997

• YN001 for ASCVD/Cerebrovascular Disease with Erectile Dysfunction

  A randomized, blinded study tests whether YN001 helps men with atherosclerotic cardiovascular disease and erectile dysfunction better than a placebo.

  Recruiting Phase 2 Beijing Inno Medicine Co., Ltd. · Beijing, Jilin · NCT07311330

• Integrated, nurse-led digital remote monitoring for cardiovascular risk management

  This observational program tests a nurse-led, at-home telemonitoring care pathway to help adults with ASCVD, hypertension, or dyslipidemia better manage blood pressure and cholesterol.

  Recruiting Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · Amsterdam, North Holland · NCT07208331

• Muvalaplin to lower major heart and stroke events in adults with high lipoprotein(a)

  This study tests whether muvalaplin can lower the chance of heart attack, stroke, or other major cardiovascular events in adults with high lipoprotein(a) who have or are at risk for cardiovascular disease.

  Recruiting at 716 sites Phase 3 Eli Lilly and Company · Birmingham, Alabama and 803 other locations · NCT07157774

• Determinants of coronary atherosclerosis in familial hypercholesterolemia

  We will use coronary CT scans to see how common hidden coronary artery plaque is in adults with familial hypercholesterolemia who do not yet have clinical heart disease.

  Recruiting at 7 sites Nantes University Hospital · Dijon and 8 other locations · NCT06960902

• Polypill plus colchicine to lower artery-related risk in people with atherosclerosis

  This study will test whether giving a daily polypill (valsartan, atorvastatin, aspirin) with or without low-dose colchicine can reduce heart attacks, strokes, or other artery-related problems in adults 45 and older who already have atherosclerotic cardiovascular disease.

  Recruiting at 13 sites Phase 3 Hospital do Coracao · Maceió, Alabama and 12 other locations · NCT06930885

Related topics

Quick answers

How many Atherosclerotic Cardiovascular Disease (ASCVD) clinical trials are recruiting right now?

10, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 30 countries. The most sites are in China (3 trials), Brazil (2 trials), France (2 trials), Hungary (2 trials), Netherlands (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 2, Phase 3: 2, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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