Exercise for erectile dysfunction and premature ejaculation

The Effectiveness of Exercise in the Treatment of Erectile Dysfunction and Premature Ejaculation: a Randomized Controlled Trial.

NA · Uskudar University · NCT07442396

This project tests whether an 8-week, three-times-weekly exercise program helps men aged 25–45 who have erectile dysfunction and premature ejaculation.

Quick facts

PhaseNA
Study typeInterventional
Enrollment50 (estimated)
Ages25 Years to 45 Years
SexMale
SponsorUskudar University (other)
Locations1 site (Istanbul)
Trial IDNCT07442396 on ClinicalTrials.gov

What this trial studies

This randomized controlled trial compared an exercise program to conventional medical follow-up in men with both erectile dysfunction and premature ejaculation. Participants were randomly assigned to a control group receiving usual medical care or to an exercise group that completed an 8-week program with sessions three days per week. Outcomes were measured before and after treatment using the International Index of Erectile Function (IIEF), the World Health Organization Quality of Life short form (WHOQOL-BREF), and the Premature Ejaculation Diagnostic Tool (PEDT). The trial enrolled physically capable men aged 25–45 and excluded those with pelvic surgery, neurological disease affecting pelvic floor function, active pelvic infections or pain, interfering psychiatric illness, or regular use of medications that strongly affect sexual function.

Who should consider this trial

Good fit: Men aged 25–45 diagnosed with both erectile dysfunction and premature ejaculation who can physically and cognitively participate in pelvic floor physiotherapy and agree to informed consent are ideal candidates.

Not a fit: Patients with prior pelvic surgery, neurological disorders affecting pelvic floor function, active pelvic infection or pain, serious psychiatric illness, or regular use of medications that significantly alter sexual function are unlikely to benefit from this protocol.

Why it matters

Potential benefit: If successful, this approach could provide a low-cost, non-drug option to improve sexual function and quality of life for affected men.

How similar studies have performed: Some prior studies of pelvic floor and aerobic exercise have reported improvements in erectile function and ejaculatory control, but results are mixed and larger confirmatory trials are limited.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria

* Male individuals aged 25-45 years
* Individuals diagnosed with erectile dysfunction and premature ejaculation
* Individuals who voluntarily agree to participate in the study and sign the informed consent form
* Individuals who have the physical and cognitive capacity to participate in pelvic floor physiotherapy applications

Exclusion Criteria

* Individuals with a history of surgery in the pelvic region
* Individuals with a diagnosis of neurological disease or neurological disorder that may affect pelvic floor muscle function
* Presence of active infection, inflammation, or painful pathology in the pelvic region
* Individuals who regularly use medications that significantly affect sexual function
* Individuals with serious psychiatric illness or cognitive impairment that may hinder study compliance

Where this trial is running

Istanbul

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Erectile Dysfunction, Premature Ejaculation

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.