Enhancing Intergenerational Heart Health in Nigeria during Pregnancy and Early Life
Official title: ENhancing Intergenerational HeAlth in Nigeria: Peripartum as Critical Life StagE for CardioVascular Health (ENHANCE-CVH)
Funded at Washington University · NIH-11617678 · Data updated 2026-11-12
A research project will test a healthy eating and active living program for pregnant women with obesity in Nigeria to help improve heart health for the mother and her children.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project start | September 5, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $215,187 |
| NIH project number | 3R01HL168771-04S1 |
| Project ID | NIH-11617678 on NIH RePORTER |
Who could benefit from this research
✓Could help
Pregnant women with obesity in Nigeria and their families.
✕Less likely to help
Pregnant women without obesity or those not participating in the program may see no direct benefit.
What this research studies
This project aims to adapt and test a HEALTH-like program during pregnancy to support healthier behaviors that can improve cardiovascular health across generations. Researchers will assess how well the program can be implemented in the Nigerian context and its impact on mothers and their children’s weight, blood pressure, and other heart health indicators. The study will enroll about 1,000 pregnant women with obesity and monitor outcomes from pregnancy through early childhood, using a combination of health measurements and community-based strategies.
Why it matters
Potential benefit: If successful, the program could reduce maternal cardiovascular risk and promote healthier heart outcomes for children as they grow.
How similar studies have gone: Previous HEALTH-style interventions have shown promise in improving diet and activity, but this study tests adaptation in Nigeria for intergenerational cardiovascular health.
Where this research is happening
-
Washington University
Saint Louis, United States Active
Researchers
- Principal investigator: Huffman, Mark D — Washington University
- Study coordinator: Huffman, Mark D
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.