Impact of pregnancy microbiomes on mom and baby heart health in a diverse group
Official title: Impact of Pregnancy Microbiomes on Maternal and Child Cardiovascular Health in a Racially and Ethnically Diverse Cohort
Funded at University of Colorado Denver · NIH-11404035 · Data updated 2026-11-12
Aimed at understanding how the microbiomes in the mother’s body relate to heart health risks for both mother and child during and after pregnancy, with a focus on diverse populations.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project start | September 1, 2025 |
| Project end | May 31, 2030 |
| Funding year | 2026 |
| Award (this year) | $690,105 |
| NIH project number | 5R01HL176997-02 |
| Project ID | NIH-11404035 on NIH RePORTER |
Who could benefit from this research
✓Could help
Pregnant individuals from diverse racial and ethnic backgrounds and their children who are part of the parent cohort, with consent to provide microbiome samples.
✕Less likely to help
People not enrolled in the cohort or without consent to provide samples may not directly benefit.
What this research studies
This project looks at how microbes from the mouth, gut, and vagina of pregnant people relate to high blood pressure disorders and future heart health for mothers and their children. Researchers will analyze microbiome samples and metabolites collected across pregnancy within an ongoing diverse cohort. The goal is to find patterns that could explain why some groups are more affected and to identify potential ways to prevent cardiovascular problems.
Why it matters
Potential benefit: If successful, it could lead to new, more equitable strategies to reduce pregnancy-related heart risks for mothers and children.
How similar studies have gone: Previous studies suggest microbiomes influence cardiovascular health, but this work aims to integrate multiple body sites and metabolites in a diverse population, which is more comprehensive.
Where this research is happening
-
University of Colorado Denver
Aurora, United States Active
Researchers
- Principal investigator: Mueller, Noel T — University of Colorado Denver
- Study coordinator: Mueller, Noel T
Related research
Other NIH-funded projects on the same topics.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.