Home visits to improve cardiovascular health for mothers and children
Official title: Early Intervention to Promote Cardiovascular Health of Mothers and Children (ENRICH)
Run by JHSPH Center for Clinical Trials · NCT06272045 · Data updated 2026-11-12
This study is testing whether a special home visiting program can help improve heart health for mothers and their children in communities at risk for cardiovascular disease.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | Women only |
| Enrollment | 6618 (estimated) |
| Sponsor | JHSPH Center for Clinical Trials Academic / other |
| Locations | 9 sites (Birmingham, Alabama and 8 other locations) |
| Status | Recruiting |
| Started | June 19, 2024 |
| Main results expected | March 30, 2028 |
| Study ends | March 30, 2029 |
| Registry record updated | April 13, 2026 |
| Trial ID | NCT06272045 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include pregnant individuals enrolled in evidence-based home visiting programs, aged 18 or older, who speak English or Spanish.
✕Probably not a fit
Patients who are not currently enrolled in an evidence-based home visiting program or are under 18 years of age may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The ENRICH initiative is a cluster randomized clinical trial aimed at enhancing cardiovascular health among mothers and their children through home visiting interventions. This study will involve 6400 participants, including 3200 parent-child dyads, recruited from diverse communities with high cardiovascular disease risk factors. The intervention will compare the effects of a structured home visiting program against usual home visiting practices, focusing on promoting cardiovascular health and reducing health disparities.
Why it matters
Potential benefit: If successful, this intervention could significantly improve cardiovascular health outcomes for mothers and their children, particularly in underserved communities.
How similar studies have gone: Other studies utilizing home visiting interventions have shown promise in improving health outcomes, suggesting that this approach may be effective.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Be currently enrolled in an evidence-based home visiting program participating in ENRICH 2. Be pregnant, with a single or multifetal gestation, at or less than 34 weeks 0 days gestation (per self-report at time of consent) 3. Be 18 years of age or older 4. Speak English or Spanish Exclusion Criteria: There are no exclusion criteria being applied in assessing eligibility for participation in ENRICH.
Where it's running
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University of Alabama at Birmingham
Birmingham, Alabama, United States Recruiting -
California Polytechnic State University
San Luis Obispo, California, United States Recruiting -
University of Colorado
Aurora, Colorado, United States Recruiting -
Northwestern University
Chicago, Illinois, United States Recruiting -
Washington University in St. Louis
St Louis, Missouri, United States Recruiting -
Wake Forest University
Winston-Salem, North Carolina, United States Recruiting
Show 3 more locations
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University of Pittsburgh
Pittsburgh, Pennsylvania, United States Recruiting -
Pennsylvania State University
State College, Pennsylvania, United States Recruiting -
Brown University/Lifespan
Providence, Rhode Island, United States Recruiting
Study contacts
- Study coordinator: Lori Burrell, MSW
- Email: lburrel1@jh.edu
- Phone: 724-858-8201
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.