NIH-funded research R01 grant

Healthy Hearts: Better Heart Screening for Survivors via Online Support

Official title: Evaluation of Cardiovascular Health Outcomes among Survivors 2 (ECHOS-2)

Funded at St. Jude Children's Research Hospital · NIH-11400309 · Data updated 2026-11-12

A new program tests if an online, nurse-guided heart-screening plan helps childhood cancer survivors stick with important heart tests.

More Cardiovascular Health research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionSt. Jude Children's Research Hospital
NIH-funded
Lab location1 site (Memphis, United States)
Project startSeptember 1, 2025
Project endAugust 31, 2030
Funding year2026
Award (this year)$688,385
NIH project number5R01CA297448-02
Project IDNIH-11400309 on NIH RePORTER

Who could benefit from this research

Could help

Childhood cancer survivors and young adults who were treated with anthracycline chemotherapy or chest-directed radiation.

Less likely to help

Survivors who do not engage with digital tools or who are not candidates for heart screening may see limited benefit.

What this research studies

This trial builds on a prior study showing a nurse-led approach improves adherence to heart screening among survivors. It tests an electronic health (eHealth) version of that approach to reach more people and make follow-up screening easier and scalable. Participants are survivors aged from childhood into adulthood who have had exposure to anthracycline chemotherapy or chest radiation, and they will be randomized to receive the eHealth intervention or usual care. The study will measure how well each group stays engaged with recommended heart screening over time. Results could show a practical way to protect long-term heart health in childhood cancer survivors.

Why it matters

Potential benefit: If successful, the program could increase early detection of heart problems and improve long-term heart health for many survivors.

How similar studies have gone: Previous APN-led strategies improved screening adherence, and an eHealth version is being tested for scalability.

Where this research is happening

  • St. Jude Children's Research Hospital
    Memphis, United States
    Active

Researchers

  • Principal investigator: Ehrhardt, Matthew James — St. Jude Children's Research Hospital
  • Study coordinator: Ehrhardt, Matthew James

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.