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Clinical trials and research at University of Sao Paulo General Hospital

• 53Clinical trials
• 4Countries

Newest trials

All recruiting trials (53)

• Red grape juice and metabolism in men with coronary disease

  Researchers will test whether daily red grape juice changes the blood metabolite profile in men with chronic coronary artery disease.

  Recruiting University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT07777341

• TRIS: a mobile app with breathalyzer to support sobriety in alcohol use disorder

  A smartphone app with a connected breathalyzer tests for abstinence and uses small financial incentives to encourage sobriety for adults with AUD in Brazil.

  Recruiting University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT07735585

• Escalation options for PAH patients already on dual therapy

  This trial tests whether adding a prostacyclin pathway drug or increasing sildenafil dose helps PAH patients at intermediate-to-high risk who aren’t at low risk despite dual therapy.

  Recruiting Phase 4 University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT07713914

• SBRT-LATTICE-PATHY for Large Tumors

  This trial tests a targeted radiotherapy approach (SBRT-LATTICE-PATHY) to treat large, intractable solid tumors in adults.

  Recruiting Phase 2 University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT07645261

• Bedside electrical imaging of lung blood flow during clot-removal surgery for CTEPH

  We will test whether bedside electrical impedance tomography (EIT) can measure regional lung blood flow before and after pulmonary thromboendarterectomy in people with chronic thromboembolic pulmonary hypertension.

  Recruiting University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT07577700

• Postpartum blood sugar screening after gestational diabetes

  This study will test whether WhatsApp reminders help women who had gestational diabetes attend a 75g OGTT at 6–12 weeks postpartum and whether the 1-hour glucose measure detects more cases of dysglycemia than the 2-hour measure.

  Recruiting University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT07489456

• High-dose cabergoline for microprolactinoma remission

  This study will try whether a short course of higher-dose cabergoline leads to more remissions than the standard low-dose approach in treatment-naïve premenopausal women with microprolactinomas.

  Recruiting at 15 sites Phase 3 University of Sao Paulo General Hospital · Belo Horizonte and 15 other locations · NCT07463235

• Improving adherence to inhaled iloprost for pulmonary arterial hypertension

  This project will test whether pharmacist-led inhaler training and adherence support helps adults with pulmonary arterial hypertension who use inhaled iloprost stick to their treatment and reduce side effects.

  Recruiting University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT07457762

• Using bedside electrical impedance tomography to detect pulmonary hypertension

  We will test whether a non-invasive bedside scan called electrical impedance tomography (EIT) can detect pulmonary hypertension in adults who are already having a right heart catheterization.

  Recruiting University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT07453017

• Vaginal versus robotic-assisted abdominal mesh repair for apical prolapse

  This study will test whether vaginal mesh repair works as well and is as safe as robotic-assisted abdominal mesh repair for women with stage II or higher apical pelvic organ prolapse.

  Recruiting University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT07359755

• Comparing two videolaryngoscopes for placing breathing tubes in infants

  This trial will test whether the BESDATA BD-DF videolaryngoscope works as well as the McGRATH MAC for placing breathing tubes on the first try in infants aged 6 months to 3 years during elective surgery.

  Recruiting University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT07351227

• Preventing HSV flares in people with autoimmune rheumatic diseases

  This trial tests whether taking acyclovir every day for a year can reduce herpes simplex recurrences in people with autoimmune rheumatic diseases who have a history of frequent HSV episodes.

  Recruiting Phase 4 University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT07341386

• Using tiny blood particles to detect and track ATTR heart amyloidosis

  This project will test whether tiny blood particles called extracellular vesicles can help detect and track transthyretin (ATTR) amyloid cardiomyopathy in people with or at risk for ATTR.

  Recruiting University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT07314268

• Clonidine to reduce craving in hospitalized people with cocaine or crack use disorder

  This will try clonidine versus clonazepam to see if clonidine lowers craving in people hospitalized for cocaine or crack use disorder.

  Recruiting Phase 4 University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT07313371

• Recombinant shingles vaccine for adults with autoimmune rheumatic diseases on single immunomodulator therapy

  This study will test whether two doses of the recombinant shingles vaccine produce strong, lasting antibody responses and are safe for adults with autoimmune rheumatic diseases who are taking a single immunomodulatory medication like hydroxychloroquine or sulfasalazine.

  Recruiting Phase 4 University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT07280741

• Antibiotic Prophylaxis Before Simple Tooth Extraction in Immunosuppressed Patients with Autoimmune Rheumatic Diseases

  This trial tests whether giving a single dose of amoxicillin before a simple tooth extraction can prevent infections in adults with autoimmune rheumatic diseases who are on immunosuppressive therapy.

  Recruiting Phase 4 University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT07275580

• MenB (Bexsero) vaccine for children and young people with autoimmune rheumatic diseases

  This project will test whether two doses of the MenB (Bexsero) vaccine produce protective antibody responses and are safe in children and young people (ages 2-25) with autoimmune rheumatic diseases compared with non-immunosuppressed peers.

  Recruiting at 2 sites Phase 4 University of Sao Paulo General Hospital · São Paulo, São Paulo and 1 other locations · NCT07252804

• PCV20 pneumococcal vaccine for children and young adults with autoimmune rheumatic diseases

  This study will test if the 20‑valent pneumococcal vaccine (PCV20) is safe and triggers antibody and cellular immune responses in people aged 2–25 with autoimmune rheumatic diseases.

  Recruiting Phase 4 University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT07252791

• Discontinuing Methotrexate for 2 Weeks After PCV20 to See If Immunity Improves

  This trial tests whether stopping methotrexate for two weeks after the PCV20 vaccine helps adults with autoimmune rheumatic diseases develop a stronger immune response.

  Recruiting Phase 4 University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT07242092

• Percutaneous stellate ganglion block for electrical storm

  This trial will try a targeted nerve block using lidocaine and bupivacaine to stop repeated ventricular arrhythmias in adults whose electrical storm hasn't responded to initial treatments.

  Recruiting Phase 4 University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT07211347

• Vaginal fractional CO2 laser versus topical promestriene for vaginal dryness in Sjögren's disease

  This trial will test whether monthly vaginal fractional CO2 laser or ongoing topical promestriene helps women with Sjögren's disease who have vaginal dryness.

  Recruiting Phase 4 University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT07153276

• Hand ultrasound and clinical follow-up after carpal tunnel release

  This project will try to see if changes in median nerve size on hand ultrasound after open carpal tunnel release match how people's symptoms, sensation, and strength improve over six months.

  Recruiting University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT07134361

• Testing a patient questionnaire about pulmonary hypertension knowledge

  This project will test a questionnaire to measure what adults with pulmonary arterial hypertension know about their condition, treatments, and self-care.

  Recruiting University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT07120789

• Losartan after aortic valve replacement to help the heart recover

  This trial will try if taking losartan after aortic valve replacement helps the heart shrink back to a healthier size and improve recovery in adults who had severe aortic regurgitation.

  Recruiting Phase 4 University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT07099859

• Butantan live tetravalent dengue vaccine for people with autoimmune rheumatic diseases

  This study will test whether a single dose of the Butantan live tetravalent dengue vaccine is safe and produces immune responses in clinically stable people aged 12–59 with autoimmune rheumatic diseases compared with matched healthy volunteers.

  Recruiting at 2 sites Phase 4 University of Sao Paulo General Hospital · São Paulo, São Paulo and 1 other locations · NCT07087912

• Switching endothelin receptor medicines and risk in pulmonary arterial hypertension

  This study will try switching adults with PAH from ambrisentan to bosentan to see if the change alters their clinical risk profile and liver safety.

  Recruiting University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT07013149

• How sitting habits relate to depressive symptoms

  This trial will test whether a physical activity program that reduces passive sitting (like TV time) helps adults over 17 with mild to severe depressive symptoms feel better.

  Recruiting at 2 sites University of Sao Paulo General Hospital · São Paulo, SO and 1 other locations · NCT07007234

• Timing of pulmonary arterial hypertension diagnosis in Brazil

  We will see how long it takes adults with pulmonary arterial hypertension in Brazil to get a confirmed diagnosis and what causes delays.

  Recruiting University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT06998329

• Impact of a vegetarian diet and exercise on type 2 diabetes management

  This study is testing whether a strict vegetarian diet and regular exercise can help people with type 2 diabetes manage their condition better.

  Recruiting University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT06959043

• Remote mental practice to help with freezing of gait in Parkinson's disease

  This study is testing if a combination of mental exercises and physical practice can help people with Parkinson's disease who struggle with freezing while walking.

  Recruiting University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT06957405

• Examining food intake in hospitalized elderly and its effects on muscle and health outcomes

  This study looks at how much food elderly patients eat while in the hospital and how it affects their muscle strength and overall health after they go home.

  Recruiting University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT06940284

• Comparing plasma proteins and metabolites in coronary artery disease patients

  This study is trying to find new blood markers in people with different types of coronary artery disease to see if they can help predict heart problems and lead to better treatments.

  Recruiting University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT06900270

• Monitoring vital signs in patients using long-term oxygen therapy

  This study tests if using a wearable device to monitor vital signs can improve the quality of life for adults with COPD and interstitial lung disease who are on long-term oxygen therapy.

  Recruiting University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT06882265

• Improving adherence to PAH treatment with telemedicine and patient guidance

  This study will try whether regular telemedicine check-ins and guided education help people with PAH stick to their oral medications and manage side effects.

  Recruiting University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT06850792

• Epidural electrical stimulation to help patients with chronic paralysis stand and walk again

  This study is testing if a special electrical device can help people with chronic spinal cord injuries stand and walk again after a year of rehabilitation.

  Recruiting University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT06847295

• Using a special bed to reduce pressure injuries in critically ill patients

  This study is testing if a special bed can help prevent pressure injuries in critically ill adults and elderly patients on ventilators better than regular repositioning methods.

  Recruiting University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT06819943

• Digital ERAS platform to shorten hospital stay after coronary artery bypass grafting

  This project tests a digital platform based on ERAS to see if it shortens hospital stays for adults having primary isolated CABG.

  Recruiting at 2 sites University of Sao Paulo General Hospital · São Paulo, São Paulo and 1 other locations · NCT06786819

• Evaluating a rapid recovery protocol for coronary artery bypass surgery

  This study tests a new recovery plan for people having heart surgery to see if it helps them get better faster compared to the usual care.

  Recruiting University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT06713096

• Supplemental oxygenation for young children during intubation

  This study tests if giving extra oxygen through a small tube in the nose can help young children breathe better during intubation and make the process safer.

  Recruiting at 4 sites University of Sao Paulo General Hospital · Perth, Western Australia and 3 other locations · NCT06683599

• Using Transcranial Magnetic Stimulation to Prevent Cognitive Issues After Surgery in Older Adults

  This study tests if using Transcranial Magnetic Stimulation can help older adults avoid memory and thinking problems after surgery.

  Recruiting University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT06658769

• Comparing oronasal and nasal CPAP with chinstrap for sleep apnea

  This study is testing whether using an oronasal mask or a nasal mask with a chinstrap helps people with sleep apnea reduce unwanted air leaks during CPAP treatment.

  Recruiting University of Sao Paulo General Hospital · São Paulo, Brazil · NCT06570629

• Managing unintentional leaks in CPAP therapy for sleep apnea

  This study is testing two different types of CPAP machines to see which one helps people with sleep apnea reduce unintentional leaks while they sleep.

  Recruiting at 2 sites University of Sao Paulo General Hospital · São Paulo, Brazil and 1 other locations · NCT06570616

• Effects of resistance training for patients waiting for heart transplants

  This study tests if a resistance training program can help heart failure patients waiting for a transplant feel better and improve their overall health.

  Recruiting University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT06426173

• Subdermal estradiol and testosterone implants for relieving menopausal symptoms

  This project will try bioabsorbable subdermal estradiol and testosterone implants in women with menopause-related estrogen and testosterone deficiency to see if they reduce menopausal and sexual symptoms.

  Recruiting Phase 3 University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT06343870

• Combining exercise with electrical stimulation for heart failure patients using an intra-aortic balloon pump

  This study is testing if adding electrical stimulation to an exercise program can help heart failure patients using an intra-aortic balloon pump get stronger and feel better compared to just doing the exercise alone.

  Recruiting University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT06316349

• Investigating physical changes in patients after lung surgery

  This study looks at how lung surgery affects the physical performance, lung function, and muscle strength of patients as they recover over time.

  Recruiting University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT06286891

• One-year comparison of radial artery versus no-touch saphenous vein grafts in women having coronary bypass surgery

  This test compares whether a radial artery graft or a 'no-touch' saphenous vein graft stays open better for one year in women undergoing coronary bypass surgery.

  Recruiting University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT06179329

• Using elastic tape to improve rehabilitation in COPD patients

  This study is testing if using elastic tape on the chest and abdomen can help people with COPD feel better and improve their physical and mental health during rehabilitation.

  Recruiting University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT05939999

• Using hypertonic saline to prevent kidney injury after heart transplantation

  This study is testing if a special salt solution can help prevent kidney problems in people who are having heart transplants.

  Recruiting Phase 2 University of Sao Paulo General Hospital · São Paulo · NCT05909150

• Using shock wave therapy to treat jaw pain from muscle disorders

  This study is testing if shock wave therapy can help people with jaw pain from muscle disorders feel better and improve their daily life.

  Recruiting University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT05907239

• Embolization treatment for patients with hereditary bleeding disorders

  This study is testing whether a new treatment using tiny particles can help people with hereditary bleeding disorders and joint pain feel better and improve their quality of life.

  Recruiting University of Sao Paulo General Hospital · São Paulo · NCT05629130

• Comparing aerobic training and behavioral intervention to boost physical activity in asthma patients

  This study is testing whether aerobic training or behavioral strategies can help adults with moderate to severe asthma become more active and improve their quality of life.

  Recruiting University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT05364632

• Effects of protein and electrical stimulation on muscle mass in elderly hospitalized patients

  This study tests if giving protein and using electrical stimulation can help elderly patients in the hospital build muscle and improve their recovery.

  Recruiting University of Sao Paulo General Hospital · São Paulo · NCT05008705

Quick answers

How many clinical trials run by University of Sao Paulo General Hospital are recruiting right now?

53, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 4 countries. The most sites are in Brazil (53 trials), Australia (1 trial), Canada (1 trial), Sweden (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 12, Phase 3: 2, Phase 2: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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