Comparing aerobic training and behavioral intervention to boost physical activity in asthma patients
Effects of Aerobic Training Versus Behavioral Intervention to Increase Physical Activity in Patients With Asthma: a Randomized, Blinded Clinical Trial.
This study is testing whether aerobic training or behavioral strategies can help adults with moderate to severe asthma become more active and improve their quality of life.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 56 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | University of Sao Paulo General Hospital Academic / other |
| Locations | 1 site (São Paulo, São Paulo) |
| Trial ID | NCT05364632 on ClinicalTrials.gov |
What this trial studies
This study aims to evaluate the effectiveness of two different interventions—aerobic training and behavioral intervention—in increasing physical activity levels among adults with moderate to severe asthma. Participants will be randomly assigned to either an aerobic training group, which involves treadmill workouts twice a week for 45 minutes, or a behavioral intervention group, which focuses on strategies to enhance physical activity once a week for up to 90 minutes. Both interventions will last for eight weeks, and the study will assess their impact on asthma control and quality of life. The maximum heart rate for aerobic training will be calculated using a specific formula based on the participant's age.
Who should consider this trial
Good fit: Ideal candidates for this study are adults with moderate to severe asthma who are currently not physically active.
Not a fit: Patients who are already engaged in regular physical activity or have other chronic conditions that limit their ability to exercise may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved asthma control and enhanced quality of life for patients through increased physical activity.
How similar studies have performed: Previous studies have shown positive outcomes with similar interventions aimed at increasing physical activity in asthma patients, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Participants not physically active; 2. Uncontrolled asthma (ACQ\>1,5); 3. Diagnosis of asthma based on the recommendations of the Global Initiative for Asthma (GINA 2020); 4. Be under outpatient follow-up at the Pulmonology or Immunology service of the University of Sao Paulo General Hospital; 5. Be under outpatient medical treatment for at least six months, with a stable clinical condition for at least 30 days; 6. Being using optimized drug therapy for asthma. Exclusion Criteria: 1. Participation in another research protocol; 2. Difficulty in understanding any of the questionnaires used; 3. Practitioners of regular physical activity; 4. Pregnancy and psychiatric problems that make it difficult to understand the questionnaires and the study protocol; 5. Presence of another chronic lung, neurological or musculoskeletal disease that hinders or prevents physical activity; 6. Patients who are smokers or ex-smokers (who have quit smoking for less than 1 year or who have smoked more than 15 pack-years).
Where this trial is running
São Paulo, São Paulo
- Clinical Hospital of São Paulo University medical school (HCFMUSP) — São Paulo, São Paulo, Brazil (Recruiting)
Study contacts
- Study coordinator: Celso RF Carvalho, PhD
- Email: cscarval@usp.br
- Phone: 55 11 98415-3234
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.