Investigating physical changes in patients after lung surgery

Evaluation of Frailty, Physical Capacity and Lung Function in Postoperative Pulmonary Endarterectomy Patients: an Observational and Prospective Clinical Study

Observational University of Sao Paulo General Hospital · NCT06286891

This study looks at how lung surgery affects the physical performance, lung function, and muscle strength of patients as they recover over time.

Quick facts

Study typeObservational
Enrollment50 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Sao Paulo General Hospital Academic / other
Locations1 site (São Paulo, São Paulo)
Trial IDNCT06286891 on ClinicalTrials.gov

What this trial studies

This observational study aims to assess the physical performance, lung function, and muscle strength of patients undergoing pulmonary endarterectomy (PET) during their recovery. Participants aged 18 and older will be evaluated at multiple time points: preoperatively, after ICU discharge, before hospital discharge, and six months post-surgery. Various tests, including the Six-minute walk test and spirometry, will be utilized to measure changes in physical capacity and identify factors contributing to functional loss during hospitalization.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older scheduled for elective pulmonary endarterectomy surgery without cognitive or motor impairments.

Not a fit: Patients requiring reoperation or those with cognitive or peripheral motor impairments may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance postoperative care and rehabilitation strategies for patients undergoing pulmonary endarterectomy.

How similar studies have performed: While similar studies have explored postoperative outcomes in lung surgery, this specific focus on frailty and physical capacity in PET patients is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥ 18 years
* Both genders
* Elective pulmonary endarterectomy surgery
* Absence of cognitive or peripheral motor impairment that prevents the performance of functional tests in the preoperative period.

Exclusion Criteria:

* Reoperation for any reason
* Presence of cognitive or peripheral motor impairment that prevents the performance of functional tests in the postoperative period.

Where this trial is running

São Paulo, São Paulo

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Chronic Thromboembolic Pulmonary HypertensionPhysical DisabilityFragilityPulmonary Endarterectomy SurgerySix-minute walk testShort Physical Performance BatteryOne-minute sit-to-stand testMuscular strength
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.