Clinical trial Recruiting at 1 site Observational Ages 18 and up

Investigating physical changes in patients after lung surgery

Official title: Evaluation of Frailty, Physical Capacity and Lung Function in Postoperative Pulmonary Endarterectomy Patients: an Observational and Prospective Clinical Study

Run by University of Sao Paulo General Hospital · NCT06286891 · Data updated 2026-11-12

This study looks at how lung surgery affects the physical performance, lung function, and muscle strength of patients as they recover over time.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment50 (estimated)
SponsorUniversity of Sao Paulo General Hospital
Academic / other
Locations1 site (São Paulo, São Paulo)
StatusRecruiting
StartedFebruary 29, 2024
Main results expectedSeptember 1, 2025
Study endsNovember 30, 2026
Registry record updatedJune 22, 2026
Trial IDNCT06286891 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 and older scheduled for elective pulmonary endarterectomy surgery without cognitive or motor impairments.

Probably not a fit

Patients requiring reoperation or those with cognitive or peripheral motor impairments may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess the physical performance, lung function, and muscle strength of patients undergoing pulmonary endarterectomy (PET) during their recovery. Participants aged 18 and older will be evaluated at multiple time points: preoperatively, after ICU discharge, before hospital discharge, and six months post-surgery. Various tests, including the Six-minute walk test and spirometry, will be utilized to measure changes in physical capacity and identify factors contributing to functional loss during hospitalization.

Why it matters

Potential benefit: If successful, this study could enhance postoperative care and rehabilitation strategies for patients undergoing pulmonary endarterectomy.

How similar studies have gone: While similar studies have explored postoperative outcomes in lung surgery, this specific focus on frailty and physical capacity in PET patients is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥ 18 years
* Both genders
* Elective pulmonary endarterectomy surgery
* Absence of cognitive or peripheral motor impairment that prevents the performance of functional tests in the preoperative period.

Exclusion Criteria:

* Reoperation for any reason
* Presence of cognitive or peripheral motor impairment that prevents the performance of functional tests in the postoperative period.

Where it's running

  • Instituto do Coração - Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
    São Paulo, São Paulo, Brazil
    Recruiting

Study contacts

  • Principal investigator: Rafael M Ianotti, PT — Instituto do Coração - Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
  • Study coordinator: Rafael M Ianotti, PT
  • Email: rafael.ianotti@hc.fm.usp.br
  • Phone: +55 11 26615319

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.