Timing of pulmonary arterial hypertension diagnosis in Brazil

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This multicenter observational project will collect medical-record and patient-journey data from Brazilian PAH reference centers to measure time from first symptom to confirmed diagnosis. Eligible adults must have Group 1 PAH confirmed by right heart catheterization and documented or reliably estimated dates for symptom onset and diagnosis. Patients with non–Group 1 pulmonary hypertension, insufficient records, or diagnoses made only by echocardiography will be excluded. Analysis will identify common misdiagnoses, referral patterns, and system or patient factors associated with longer diagnostic delays.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Availability of documented or estimated date of first symptom suggestive of PAH.
* Availability of documented date of confirmed PAH diagnosis.

Exclusion Criteria:

* Patients with pulmonary hypertension not classified as Group 1 (e.g., due to left heart disease, chronic lung disease, or chronic thromboembolic disease).
* Patients with insufficient data to determine either the date of symptom onset or the date of confirmed diagnosis.
* Patients diagnosed only clinically or by echocardiography, without confirmation by right heart catheterization.

Where it's running

• InCor - Universidade de São Paulo
  São Paulo, São Paulo, Brazil Recruiting

Study contacts

• Study coordinator: Caio Fernandes, PhD
• Email: caio.cesar@hc.fm.usp.br
• Phone: +55 11 2661-1548

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Switching endothelin receptor medicines and risk in pulmonary arterial hypertension

  This study will try switching adults with PAH from ambrisentan to bosentan to see if the change alters their clinical risk profile and liver safety.

  Recruiting University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT07013149

• Improving adherence to PAH treatment with telemedicine and patient guidance

  This study will try whether regular telemedicine check-ins and guided education help people with PAH stick to their oral medications and manage side effects.

  Recruiting University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT06850792

• Rutgers Genetics of Pulmonary Hypertension

  This online project will try to see if genetic differences affect the risk of pulmonary hypertension in U.S. adults, and anyone 18 or older can join whether or not they have PH.

  Recruiting Rutgers, The State University of New Jersey · Piscataway, New Jersey · NCT07217522

• Testing a patient questionnaire about pulmonary hypertension knowledge

  This project will test a questionnaire to measure what adults with pulmonary arterial hypertension know about their condition, treatments, and self-care.

  Recruiting University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT07120789

• Sotatercept to support right ventricular function in pulmonary arterial hypertension

  This research will try sotatercept injections in adults with PAH to see if the medicine helps the right side of the heart work better.

  Recruiting Phase 4 Amsterdam UMC, location VUmc · Amsterdam, North Holland · NCT06658522

• Sleep problems in PAH patients: how sleep breathing relates to PAH outcomes

  This study tests how sleep-disordered breathing and nocturnal oxygen changes relate to outcomes in adults with pulmonary arterial hypertension.

  Recruiting Chinese Pulmonary Vascular Disease Research Group · Beijing · NCT07852403

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.