Remote mental practice to help with freezing of gait in Parkinson's disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This trial investigates the effects of a remote intervention combining mental practice and physical practice on freezing of gait severity in individuals with idiopathic Parkinson's disease. Fifty participants will be randomly assigned to either an experimental group receiving mental and physical practice or a control group receiving only physical practice with stretching. The intervention consists of 10 video-supervised sessions over six weeks, focusing on gait-related challenges. Primary and secondary outcomes will be assessed to evaluate the effectiveness of the intervention in reducing freezing of gait and improving motor and cognitive functions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Clinical diagnosis of idiopathic PD;
* Use of dopaminergic medication;
* Experiencing FOG (positive response to the first question of the New Freezing of Gait Questionnaire - NFOG-Q);
* Able to walk independently at home;
* Access to internet and video call device;
* Agree to participate in the study.

Exclusion Criteria:

* Other neurological disorders;
* Severe cardiovascular and/or respiratory alterations;
* Uncorrected visual and/or auditory alterations;
* Cognitive impairment, detectable through the Telephone Montreal Cognitive Assessment (T-MoCA, \< 12);
* Inability to perform motor imageryT during the administration of the Kinesthetic and Visual Imagery Questionnaire - 20 (KVIQ-20, \< 20)

Where it's running

• University of Sao Paulo
  São Paulo, São Paulo, Brazil Recruiting

Study contacts

• Study coordinator: Maria Elisa P Piemonte, PT, PHD
• Email: elisapp@usp.br
• Phone: 55 11 30917451

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Decoding brain signals and DBS settings for freezing of gait in Parkinson’s

  This study tests how brain activity and different DBS settings affect freezing of gait and balance in people with Parkinson’s who already have a Medtronic Percept DBS device.

  Recruiting The Cleveland Clinic · Cleveland, Ohio · NCT07748962

• Percept recordings of brain activity during freezing of gait in Parkinson's disease

  This research will use the Medtronic Percept DBS device to test whether brain electrical patterns differ during walking, movement transitions, and freezing in people with Parkinson's disease who do and do not experience freezing of gait.

  Recruiting University of Minnesota · Minneapolis, Minnesota · NCT06848205

• Thoracic epidural spinal cord stimulation to reduce freezing of gait in advanced Parkinson's disease

  This study will try temporary thoracic spinal cord stimulation to see if it helps people with advanced Parkinson's disease whose freezing of gait does not respond to medications.

  Recruiting National Taiwan University Hospital · Hsinchu, Hsinchu City · NCT06630702

• Using deep brain stimulation and levodopa to improve walking in Parkinson's patients

  This study is testing whether increasing deep brain stimulation or giving a higher dose of levodopa helps people with Parkinson's disease walk better and reduces freezing episodes.

  Recruiting Phase 4 IRCCS Istituto delle Scienze Neurologiche di Bologna · Bologna · NCT06316232

• CereGate Therapy for Freezing of Gait in Parkinson's Disease

  This study is testing if CereGate therapy can help people with Parkinson's Disease who have freezing of gait feel more mobile and improve their movement after having deep brain stimulation.

  Recruiting at 7 sites CereGate Inc. · Redwood City, California and 6 other locations · NCT05292794

• One-day exercise test to see how brain and body react in epilepsy, cognitive disorders, Parkinson's, dementia, and related conditions

  A one-day study tests how an acute bout of exercise changes brain function and bodily signals in people with certain neurological conditions compared with healthy individuals.

  Recruiting Brigham and Women's Hospital · Boston, Massachusetts · NCT07883720

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.