How sitting habits relate to depressive symptoms
Sedentary Behavior and Depressive Symptoms: Influence of Specific Domains of Sedentary Behavior
This trial will test whether a physical activity program that reduces passive sitting (like TV time) helps adults over 17 with mild to severe depressive symptoms feel better.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 84 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Sao Paulo General Hospital Academic / other |
| Locations | 2 sites (São Paulo, SO and 1 other locations) |
| Trial ID | NCT07007234 on ClinicalTrials.gov |
What this trial studies
Adults with mild to severe depressive symptoms are randomized to a physical activity intervention or to standard care at a university site in São Paulo. The intervention targets reductions in sedentary behavior, with attention to mentally passive versus mentally active sitting, and increases in physical activity. Outcomes include changes in depressive symptom scores, physical performance measures, and cardiometabolic risk indicators. Key exclusions include recent cancer, muscle degenerative disease, or inability to perform required physical tests.
Who should consider this trial
Good fit: Adults older than 17 who have mild to severe depressive symptoms and who can complete physical assessments and attend visits in São Paulo.
Not a fit: People with cancer in the past five years, diagnosed muscle-degenerative diseases, or those unable to perform the physical tests may not benefit or be eligible.
Why it matters
Potential benefit: If successful, the program could lower depressive symptoms and reduce cardiometabolic risk by replacing passive sitting with more active behaviors.
How similar studies have performed: Previous research shows physical activity can reduce depressive symptoms and emerging evidence suggests different types of sitting have different health effects, but results are mixed and targeted trials are limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * individuals aged over 17 years; * mild to severe depressive symptoms. Exclusion Criteria: * cancer in the past 5 years; * inability to perform the physical tests; * prior diagnosis of muscle degenerative disease (e.g., myopathies, amyotrophic lateral sclerosis);
Where this trial is running
São Paulo, SO and 1 other locations
- University of Santo Amaro — São Paulo, So, Brazil (Recruiting)
- University Santo Amaro — São Paulo, São Paulo, Brazil (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.