How sitting habits relate to depressive symptoms
Official title: Sedentary Behavior and Depressive Symptoms: Influence of Specific Domains of Sedentary Behavior
Run by University of Sao Paulo General Hospital · NCT07007234 · Data updated 2026-11-12
This trial will test whether a physical activity program that reduces passive sitting (like TV time) helps adults over 17 with mild to severe depressive symptoms feel better.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 84 (estimated) |
| Sponsor | University of Sao Paulo General Hospital Academic / other |
| Locations | 2 sites (São Paulo, SO and 1 other locations) |
| Status | Recruiting |
| Started | June 1, 2025 |
| Main results expected | July 1, 2026 |
| Study ends | July 1, 2026 |
| Registry record updated | July 25, 2025 |
| Trial ID | NCT07007234 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults older than 17 who have mild to severe depressive symptoms and who can complete physical assessments and attend visits in São Paulo.
✕Probably not a fit
People with cancer in the past five years, diagnosed muscle-degenerative diseases, or those unable to perform the physical tests may not benefit or be eligible.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Adults with mild to severe depressive symptoms are randomized to a physical activity intervention or to standard care at a university site in São Paulo. The intervention targets reductions in sedentary behavior, with attention to mentally passive versus mentally active sitting, and increases in physical activity. Outcomes include changes in depressive symptom scores, physical performance measures, and cardiometabolic risk indicators. Key exclusions include recent cancer, muscle degenerative disease, or inability to perform required physical tests.
Why it matters
Potential benefit: If successful, the program could lower depressive symptoms and reduce cardiometabolic risk by replacing passive sitting with more active behaviors.
How similar studies have gone: Previous research shows physical activity can reduce depressive symptoms and emerging evidence suggests different types of sitting have different health effects, but results are mixed and targeted trials are limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * individuals aged over 17 years; * mild to severe depressive symptoms. Exclusion Criteria: * cancer in the past 5 years; * inability to perform the physical tests; * prior diagnosis of muscle degenerative disease (e.g., myopathies, amyotrophic lateral sclerosis);
Where it's running
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University of Santo Amaro
São Paulo, So, Brazil Recruiting -
University Santo Amaro
São Paulo, São Paulo, Brazil Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.