Postpartum blood sugar screening after gestational diabetes
Strategies for Improving the Detection of Dysglycemia in the Postpartum Period in Women With Gestational Diabetes: Electronic Reminders and New Diagnostic Criteria
NA · University of Sao Paulo General Hospital · NCT07489456
This study will test whether WhatsApp reminders help women who had gestational diabetes attend a 75g OGTT at 6–12 weeks postpartum and whether the 1-hour glucose measure detects more cases of dysglycemia than the 2-hour measure.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 182 (estimated) |
| Sex | Female |
| Sponsor | University of Sao Paulo General Hospital (other) |
| Locations | 1 site (São Paulo, São Paulo) |
| Trial ID | NCT07489456 on ClinicalTrials.gov |
What this trial studies
Women diagnosed with gestational diabetes at the University of Sao Paulo General Hospital will be scheduled for a 75g oral glucose tolerance test between six and 12 weeks after delivery. The intervention uses WhatsApp reminders to try to increase attendance for the OGTT compared with usual care. During the OGTT the team will record fasting, 1-hour, and 2-hour glucose values to compare how often the 1-hour versus 2-hour measurements identify dysglycemia. Data will be analyzed to quantify any change in attendance and the relative detection rates of postpartum dysglycemia using the different time points.
Who should consider this trial
Good fit: Women diagnosed with gestational diabetes by IADPSG criteria who delivered at HC-FMUSP, can schedule a 75g OGTT 6–12 weeks after delivery, and provide informed consent are eligible.
Not a fit: Women who withdraw consent, cannot receive or respond to WhatsApp messages, or who cannot complete the OGTT (for example due to vomiting) are unlikely to benefit from the intervention.
Why it matters
Potential benefit: If successful, this approach could increase postpartum OGTT attendance and lead to earlier detection of prediabetes or type 2 diabetes after gestational diabetes.
How similar studies have performed: Previous research has shown electronic reminders can improve clinic attendance and some studies suggest the 1-hour OGTT glucose may be more sensitive than the 2-hour value for early postpartum dysglycemia, so this project builds on existing evidence.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosis of gestational diabetes mellitus, according to diagnostic criteria proposed by the IADPSG, namely: * initial fasting blood glucose ≥ 92mg/dL OR * 75g oral glucose tolerance test with fasting ≥ 92mg/dL or after 1h ≥ 180mg/dL or after 2h ≥ 153mg/dL Delivery performed at HC-FMUSP Scheduling of the 75g oral glucose tolerance test between 6 and 12 weeks after delivery Agreement with the informed consent form Exclusion Criteria: Withdrawal of consent Failure to complete the TOTG exam due to vomiting (exclusion from analysis 2 only)
Where this trial is running
São Paulo, São Paulo
- University of Sao Paulo General Hospital — São Paulo, São Paulo, Brazil (RECRUITING)
Study contacts
- Study coordinator: Tatiana A Zaccara, MD PhD
- Email: tatiana.assuncao@hc.fm.usp.br
- Phone: +551126616209
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Gestational Diabetes Mellitus, dysglycemia, gestational diabetes, prediabetes, diabetes, postpartum OGTT