Effects of protein and electrical stimulation on muscle mass in elderly hospitalized patients
Effects of Protein Intake Plus Neuromuscular Electrical Stimulation on Muscle Mass in Hospitalized Elderly: a Randomized Controlled Clinical Study
This study tests if giving protein and using electrical stimulation can help elderly patients in the hospital build muscle and improve their recovery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Ages | 65 Years and up |
| Sex | All |
| Sponsor | University of Sao Paulo General Hospital Academic / other |
| Locations | 1 site (São Paulo) |
| Trial ID | NCT05008705 on ClinicalTrials.gov |
What this trial studies
This study investigates how protein supplementation combined with neuromuscular electrical stimulation can affect muscle mass, hospital stay duration, readmission rates, and mortality in elderly patients. The focus is on hospitalized individuals who often experience malnutrition and muscle wasting due to inactivity and inflammation. Participants will receive either the protein and stimulation intervention or a placebo and sham stimulation to assess the effectiveness of the treatment. The study aims to provide insights into improving outcomes for elderly patients during hospitalization.
Who should consider this trial
Good fit: Ideal candidates are hospitalized individuals aged 65 and older who have been admitted for less than 48 hours.
Not a fit: Patients with recent cancer, cognitive deficits, or neurological diseases may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve muscle mass and reduce hospital stay and readmission rates for elderly patients.
How similar studies have performed: Other studies have shown promising results with similar interventions in improving muscle mass and outcomes in elderly populations.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * both sex; * 65 years and older; * hospital stay less than 48 hours; Exclusion Criteria: * cancer in the last 5 years; * delirium; * cognitive deficit that impossibility the patient to read and sign the informed consent form; * neurological disease; * neurodegenerative muscular disease; * impossibility to receive the intervention.
Where this trial is running
São Paulo
- University of Sao Paulo — São Paulo, Brazil (Recruiting)
Study contacts
- Principal investigator: Hamilton Roschel, PhD — University of Sao Paulo General Hospital
- Study coordinator: Hamilton Roschel, PhD
- Email: hars@usp.br
- Phone: +551130618789
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.