Embolization treatment for patients with hereditary bleeding disorders

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This longitudinal, prospective study aims to evaluate the effects of superselective embolization on patients with hereditary coagulopathies suffering from chronic synovitis due to hemarthrosis in their joints. A total of 30 subjects will undergo imaging tests, physical assessments, and quality of life evaluations at multiple time points over five years. The embolization procedure involves using spherical microparticles to achieve partial vascular stasis in the affected joints, potentially alleviating symptoms and improving joint health. The study will be conducted at the Centro de Hemofilia do Hospital das Clinicas, Faculdade de Medicina da Universidade de São Paulo.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with hereditary coagulopathies with arthropathy (i.e., chronic synovitis due to hemarthrosis), with X-ray and MRI (documenting synovitis) followed up at the Hemophilia Center HC-FMUSP.

Exclusion Criteria:

* Patients who do not complete the planned assessments
* Patients who do not accept to continue with the study.

Where it's running

• Instituto de Ortopedia e Traumatologia do Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo
  São Paulo, Brazil Recruiting

Study contacts

• Principal investigator: Fabiane E FArias, PT — IOT-HC-FMUSP (Orthopedics Institute - General Hospital- School of Medicine - University of Sao Paulo
• Study coordinator: marcia u rezende, MD PhD
• Email: marcia.uchoa@hc.fm.usp.br
• Phone: +5511 981226282

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.