Supplemental oxygenation for young children during intubation

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the use of supplemental oxygen via nasal cannula during the intubation process in neonates and infants. It aims to improve the safety and success rate of tracheal intubation by extending the safe apnea time and reducing the risk of desaturation. Eligible participants will undergo standard anesthesia induction procedures, followed by pre-oxygenation and apneic oxygenation techniques. The study will monitor vital signs to assess the effectiveness of the intervention.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Pediatric patients requiring oral or nasal tracheal intubation for elective, semi-elective, or urgent surgical and non-surgical procedures.
* Neonates and infants up to 52 weeks post-conceptual age.
* Written informed consent provided by legal guardians prior to the intervention.

Exclusion Criteria:

* Prediction of difficult intubation based on physical examination or a history of previous difficult intubation.
* Requirement for an alternative technique to direct laryngoscopy to secure the airway.
* Specific conditions, such as congenital heart disease requiring FiO₂ \< 1.0, or cardiopulmonary collapse necessitating advanced life support and intubation for emergency surgical or non-surgical interventions.

Where it's running

• Perth Children's Hospital
  Perth, Western Australia, Australia Recruiting
• Hospital das Clinicas HCFMUSP
  São Paulo, São Paulo, Brazil Recruiting
• British Columbia Children's Hospital
  Vancouver, British Columbia, Canada Recruiting
• Uppsala University Hospital
  Uppsala, Sweden Recruiting

Study contacts

• Principal investigator: Vinicius C Quintao, MD, MSc, PhD — Hospital das Clinicas, Faculdade de Medicina, Universidade de Sao Paulo
• Study coordinator: Vinicius C Quintao, MD, MSc, PhD
• Email: vinicius.quintao@hc.fm.usp.br
• Phone: + 55 11 97127-3950

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.