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Clinical trials and research at City of Hope Medical Center

• 159Clinical trials
• 10Countries

Newest trials

All recruiting trials (newest 150 of 159)

• Exercise after pelvic radiation to see if it lowers colorectal cancer risk

  This study tests whether regular walking therapy after pelvic radiation for prostate cancer can influence markers of colorectal cancer in colon tissue and blood.

  Recruiting at 2 sites City of Hope Medical Center · Duarte, California and 1 other locations · NCT07790718

• Tear Fluid for Detecting Tumor-Linked Particles in Glioblastoma

  This study tests whether tear fluid can reveal tumor-associated particles in people with glioblastoma, potentially offering a easier way to monitor the cancer.

  Recruiting City of Hope Medical Center · Duarte, California · NCT07775534

• Blended e-Health Program to Help Women with Breast or Gynecologic Cancer Manage Fear of Cancer Progression

  This trial tests a blended online and group program to see if it helps women with breast or gynecologic cancer feel less fear that their cancer could grow or spread.

  Recruiting at 11 sites City of Hope Medical Center · Arcadia, California and 10 other locations · NCT07741968

• Mindfulness program to help with symptoms in chronic graft-versus-host disease

  A mindfulness-based program is being tested to see if it can reduce patient-reported symptoms for adults with chronic graft-versus-host disease after a stem cell transplant.

  Recruiting City of Hope Medical Center · Duarte, California · NCT07733141

• Sacral Reflex Monitoring During Surgery to Predict Postoperative Function

  This study tests whether watching sacral nerve reflexes during sacrectomy or related spine surgeries can help predict how a patient will function after surgery.

  Recruiting City of Hope Medical Center · Duarte, California · NCT07707024

• Belinostat combined with azacitidine or pralatrexate for relapsed or refractory TFH/Nodal PTCL and related T-cell lymphomas

  This early-phase trial tests whether adding belinostat to azacitidine or pralatrexate is safe and may help treat adults with relapsed or refractory follicular helper T-cell lymphoma and related T-cell cancers.

  Recruiting at 2 sites Phase 1 City of Hope Medical Center · Duarte, California and 1 other locations · NCT07691450

• Environmental exposure checks in high-risk and early-onset breast cancer care

  This study tests how patients and providers feel about using environmental exposure risk data in breast cancer care for women at average/high risk or with early-onset breast cancer.

  Recruiting City of Hope Medical Center · Duarte, California · NCT07690852

• High Fiber Program to see if more fiber helps patients after an allogeneic stem cell transplant

  This program tests whether a high-fiber diet can help adults undergoing allogeneic hematopoietic cell transplant eat more fiber and feel better.

  Recruiting City of Hope Medical Center · Duarte, California · NCT07664670

• Couples Coping Together Against Cancer: A Feasibility and Acceptability Look

  This observational study tests whether a brokered program for patients with cancer and their partners is feasible and acceptable, and whether it may reduce distress over time.

  Recruiting City of Hope Medical Center · Duarte, California · NCT07664579

• Fluorescence-guided surgery to reduce unexpected positive margins in high-grade sarcoma

  This phase II trial tests whether adding fluorescence-guided surgery with indocyanine green can lower unexpected positive margins in patients with high-grade sarcoma compared to standard surgery.

  Recruiting Phase 2 City of Hope Medical Center · Duarte, California · NCT07650656

• 64Cu-DOTA-Pembrolizumab PET to See If Treatment Is Working in Stage IV NSCLC

  This study tests a new PET imaging agent paired with pembrolizumab to see if it can show which tumors are still responding in adults with stage IV NSCLC who are already receiving pembrolizumab.

  Recruiting Phase 1 City of Hope Medical Center · Duarte, California · NCT07619599

• Individualized AML Treatment using patient-specific drug screening

  This study tests whether high-throughput drug screening plus comprehensive genetic testing can help choose the best treatment for adults with relapsed or refractory AML.

  Recruiting City of Hope Medical Center · Duarte, California · NCT07613385

• Neoadjuvant Botensilimab and Balstilimab for Advanced Resectable Colorectal Cancer

  This phase 2 trial tests whether giving botensilimab and balstilimab before surgery can help patients with advanced, resectable colorectal cancer see better outcomes.

  Recruiting at 11 sites Phase 2 City of Hope Medical Center · Goodyear, Arizona and 10 other locations · NCT07595874

• Molecular profiling to improve risk stratification in appendiceal cancer

  Researchers test DNA methylation and m6A epitranscriptomic features in archived appendiceal cancer tissue to see if molecular subtypes and risk scores can better predict outcomes.

  Recruiting City of Hope Medical Center · Durate, California · NCT07587268

• Prediction of chemotherapy response in gastric cancer using RNA splicing

  Researchers will test whether RNA splicing patterns in tumor tissue can predict which gastric cancer patients will respond to 5-FU-based chemotherapy.

  Recruiting City of Hope Medical Center · Duarte, California · NCT07587229

• Nemtabrutinib plus rituximab for marginal zone lymphoma

  This phase 2 trial tests whether combining nemtabrutinib with rituximab can help people with marginal zone lymphoma.

  Recruiting Phase 2 City of Hope Medical Center · Duarte, California · NCT07583810

• Total marrow and lymphoid irradiation with fludarabine and melphalan for older adults with refractory/relapsed AML or high-risk MDS undergoing donor stem cell transplant

  This phase 2 trial tests a targeted radiation conditioning (TMLI) with fludarabine and melphalan before a matched donor stem cell transplant in people aged 50 or older with difficult-to-treat AML or high-risk MDS.

  Recruiting Phase 2 City of Hope Medical Center · Duarte, California · NCT07582172

• Tafasitamab plus Acalabrutinib and Venetoclax for newly treated CLL/SLL

  This phase II study tests a combination of tafasitamab, acalabrutinib, and venetoclax in adults who are newly diagnosed with chronic lymphocytic leukemia or small lymphocytic lymphoma to see if it is safe and effective.

  Recruiting at 2 sites Phase 2 City of Hope Medical Center · Duarte, California and 1 other locations · NCT07582159

• Golgadomide plus rituximab for relapsed or refractory mantle cell lymphoma

  This phase I/II trial tests whether golcadomide given with rituximab is safe and can help people with mantle cell lymphoma that has come back or stopped responding to treatment.

  Recruiting Phase 1/2 City of Hope Medical Center · Duarte, California · NCT07578077

• Locally delivered EGFR/IL13Rα2 CAR T-cell therapy for recurrent high-grade gliomas

  This phase I study tests whether a patient's own EGFR/IL13Rα2 CAR T cells, given directly into the brain, are safe and can help adults with recurrent or progressive high-grade gliomas.

  Recruiting Phase 1 City of Hope Medical Center · Duarte, California · NCT07544992

• Epcoritamab plus R-GemOx before autologous stem cell transplant for relapsed or refractory DLBCL

  This phase II trial tests whether adding epcoritamab to rituximab with gemcitabine and oxaliplatin (R-GemOx) can help adults with relapsed or refractory diffuse large B-cell lymphoma (DLBCL) achieve remission and proceed to autologous stem cell transplant.

  Recruiting Phase 2 City of Hope Medical Center · Duarte, California and 2 other locations · NCT07365306

• Duvelisib maintenance after first-line therapy for peripheral T-cell lymphomas

  This phase II study tests whether taking duvelisib pills after initial treatment helps keep follicular helper T-cell and other peripheral T-cell lymphomas from coming back in adults who have responded to therapy and did not have a transplant.

  Recruiting Phase 2 City of Hope Medical Center · Duarte, California · NCT07293403

• Using blood and tissue biomarkers to guide immunotherapy and later treatment choices in advanced non-small cell lung cancer

  This trial tests whether blood and tumor biomarkers can predict who will respond to first-line PD‑1/PD‑L1 immunotherapy and help pick better second-line treatments for people with stage IIIB–IV non‑small cell lung cancer.

  Recruiting at 13 sites Phase 2 City of Hope Medical Center · Goodyear, Arizona and 12 other locations · NCT07288034

• Ruxolitinib with CHOP for untreated nodal TFH cell lymphoma

  This phase 1 trial tests whether adding ruxolitinib to CHOP chemotherapy is safe and tolerable in adults with untreated nodal TFH cell lymphoma.

  Recruiting Phase 1 City of Hope Medical Center · Duarte, California · NCT07278856

• Pembrolizumab plus chemotherapy for frail adults with classical Hodgkin lymphoma who can't get standard treatment

  This phase II trial tests whether adding pembrolizumab to gemcitabine-based chemotherapy (with possible brentuximab vedotin and dacarbazine) helps frail adults newly diagnosed with classical Hodgkin lymphoma who are ineligible for standard anthracycline-based therapy.

  Recruiting Phase 2 City of Hope Medical Center · Duarte, California · NCT07275216

• Mitomycin PIPAC plus FOLFIRI vs FOLFIRI/bevacizumab for unresectable peritoneal metastases from appendix or colorectal cancer

  This phase 3 trial tests whether pressurized intraperitoneal aerosolized chemotherapy with mitomycin, given with systemic FOLFIRI, can help patients with unresectable appendix or colorectal cancer that has spread to the abdominal lining, compared with the standard FOLFIRI plus bevacizumab.

  Recruiting Phase 3 City of Hope Medical Center · Goodyear, Arizona and 4 other locations · NCT07271355

• Blood test combining cell-free and exosomal microRNAs for early detection of esophageal squamous cell carcinoma

  This project will try a blood test that measures cell-free and exosomal microRNAs to find early esophageal squamous cell carcinoma in adults using plasma or serum samples.

  Recruiting City of Hope Medical Center · Monrovia, California · NCT07266363

• Cell-free tsRNA signature to detect early liver cancer

  This project will test whether a blood test that measures cell-free tsRNAs can detect early-stage hepatocellular carcinoma using samples from people with confirmed HCC.

  Recruiting City of Hope Medical Center · Duarte, California · NCT07265271

• Blood test of exosomal microRNAs to stage colon cancer before surgery

  This project will try a blood test that measures tumor-released exosomal microRNAs to see if it can identify patients with higher-risk colon cancer before surgery.

  Recruiting City of Hope Medical Center · Duarte, California · NCT07255729

• Blood test using exosomal microRNA to find tiny leftover gastric cancer after surgery

  This study tests a blood-based exosomal microRNA assay to see if it can detect minimal residual gastric cancer after curative surgery and predict future distant metastasis.

  Recruiting City of Hope Medical Center · Duarte, California · NCT07243015

• Immune Cells in Blood and Tissues After Allogeneic Transplant and Chronic GVHD

  This study tests whether immune cells in blood and other samples differ between people who develop chronic GVHD after an allogeneic transplant and those who don’t.

  Recruiting City of Hope Medical Center · Duarte, California · NCT07235501

• Ivonescimab given before surgery for high-risk localized clear cell kidney cancer

  This study tests whether giving ivonescimab before nephrectomy helps patients with high-risk localized clear cell renal cell carcinoma.

  Recruiting Phase 2 City of Hope Medical Center · Duarte, California · NCT07226544

• Predicting chemotherapy response in pancreatic cancer using a blood microRNA panel

  This project tests whether a panel of microRNAs in pre-treatment blood can predict response to neoadjuvant chemotherapy (FOLFIRINOX or gemcitabine plus nab‑paclitaxel) in patients with resectable or borderline resectable pancreatic cancer.

  Recruiting City of Hope Medical Center · Duarte, California · NCT07226154

• Predicting who will benefit from adjuvant chemotherapy in stage II–III colorectal cancer using tumor splicing patterns

  This project tests whether a tumor splicing signature from surgical tissue can help predict which people with stage II–III colorectal cancer will benefit from adjuvant chemotherapy.

  Recruiting City of Hope Medical Center · Duarte, California · NCT07226115

• Geriatric-guided supportive care for older adults receiving chemotherapy and radiation for head and neck cancer and their caregivers

  This project tests whether using a geriatric assessment to guide supportive care helps people aged 60+ getting chemotherapy and radiation for localized head and neck cancer and their family caregivers.

  Recruiting City of Hope Medical Center · Duarte, California · NCT07225855

• How cancer treatments and medicines, including cannabis, affect people with multiple myeloma.

  This will see if using cannabis changes quality of life, symptoms, or treatment side effects in adults newly diagnosed with multiple myeloma who are receiving first‑line therapy.

  Recruiting at 2 sites City of Hope Medical Center · Goodyear, Arizona and 10 other locations · NCT07225738

• cfDNA blood test using 5mC/5hmC to predict response to EGFR or VEGF targeted therapy in metastatic colorectal cancer

  This project will test if a blood test that measures cfDNA methylation (5mC/5hmC) can tell which people with metastatic colorectal cancer are likely to respond to EGFR- or VEGF-targeted treatments.

  Recruiting City of Hope Medical Center · Duarte, California · NCT07224841

• Blood test measuring cfDNA methylation to predict chemotherapy response in metastatic colorectal cancer

  This project will test whether a blood test that measures cfDNA 5mC/5hmC patterns can predict which people with metastatic colorectal cancer will respond to first-line FOLFOX or FOLFIRI chemotherapy.

  Recruiting City of Hope Medical Center · Duarte, California · NCT07224815

• Blood test using circular RNAs for early detection of colorectal cancer

  This project tests whether a blood test that measures circular RNAs can detect early-stage colorectal cancer in adults with newly diagnosed (stage I–III) disease.

  Recruiting City of Hope Medical Center · Duarte, California · NCT07224789

• Noninvasive blood miRNA test to screen for multiple gastrointestinal cancers.

  This project will test whether a blood-based microRNA panel can detect several types of gastrointestinal cancer in adults using stored blood samples.

  Recruiting City of Hope Medical Center · Duarte, California · NCT07224750

• Blood test using exosome microRNAs to find extrahepatic spread in colorectal cancer with liver metastases

  This project will test whether a blood test measuring exosome microRNAs can detect extrahepatic metastases in adults whose colorectal cancer has spread to the liver.

  Recruiting City of Hope Medical Center · Duarte, California · NCT07224724

• L-theanine for relaxation and mood support in cancer patients on surveillance

  This trial tests whether taking 200 mg of L-theanine once or twice daily for six weeks can help relaxation and mood in adult cancer patients who have finished treatment and are in surveillance.

  Recruiting Early Phase 1 City of Hope Medical Center · Duarte, California and 3 other locations · NCT07220447

• Combining lutetium‑177 PSMA therapy with sipuleucel‑T for advanced castration‑resistant prostate cancer

  This trial tests whether adding sipuleucel‑T to lutetium‑177 PSMA‑617 helps men with metastatic castration‑resistant prostate cancer.

  Recruiting Phase 1 City of Hope Medical Center · Duarte, California · NCT07219147

• Add Pedmark to cisplatin chemotherapy to prevent hearing loss in men with stage II–III metastatic testicular germ cell tumors

  We will test whether adding Pedmark to cisplatin chemotherapy reduces hearing damage in men with stage II–III metastatic testicular germ cell tumors.

  Recruiting Phase 1 City of Hope Medical Center · Duarte, California · NCT07218913

• Venetoclax plus obinutuzumab followed by epcoritamab for untreated CLL/SLL

  This trial tests whether giving venetoclax and obinutuzumab followed by epcoritamab can produce deep remissions in people with previously untreated chronic lymphocytic leukemia or small lymphocytic lymphoma.

  Recruiting at 4 sites Phase 2 City of Hope Medical Center · Duarte, California and 6 other locations · NCT07218510

• PSMA-PET and ctDNA monitoring after targeted radiotherapy for oligometastatic prostate cancer (PROMPT-R)

  This will see if PSMA-PET scans and blood ctDNA can detect early progression and track response after ablative radiotherapy in men with oligometastatic or oligoprogressive, hormone-sensitive prostate cancer.

  Recruiting Phase 2 City of Hope Medical Center · Duarte, California · NCT07210086

• Metabolic strategies — time‑restricted eating, GLP‑1 medicines, and a heart‑healthy diet to protect heart and metabolic health during hormone therapy for prostate cancer

  This trial tests whether time‑restricted eating or GLP‑1 drugs (semaglutide or tirzepatide), combined with heart‑healthy diet counseling, can protect heart and metabolic health in men receiving androgen‑deprivation therapy for prostate cancer.

  Recruiting Phase 2 City of Hope Medical Center · Duarte, California · NCT07202247

• Digital health program for self-management and remote monitoring during outpatient CAR-T therapy

  This Phase 3 study tests whether a remote patient-monitoring and education program helps adults with relapsed or refractory blood cancers and their family caregivers manage symptoms during and after outpatient CAR-T therapy.

  Recruiting Phase 3 City of Hope Medical Center · Duarte, California · NCT07186192

• Different types of massage to reduce anxiety during chemotherapy infusion

  This trial tests whether 30-minute massages to different body areas during chemo infusions can reduce anxiety in adult cancer patients who report at least moderate anxiety.

  Recruiting City of Hope Medical Center · Irvine, California · NCT07184294

• Erwinia asparaginase and venetoclax added to blinatumomab for relapsed/refractory CD19+ B‑ALL

  This will test whether adding recombinant Erwinia asparaginase and venetoclax to blinatumomab helps adolescents and adults (12–55) with CD19-positive relapsed or refractory B-cell acute lymphoblastic leukemia.

  Recruiting Phase 1 City of Hope Medical Center · Duarte, California · NCT07133997

• Nivolumab and ipilimumab with or without EXL01 for advanced or metastatic clear-cell and sarcomatoid renal cell carcinoma

  This trial tests whether adding EXL01, a live Faecalibacterium prausnitzii product, to nivolumab and ipilimumab helps adults with advanced or metastatic clear-cell or sarcomatoid renal cell cancer.

  Recruiting at 2 sites Phase 1 City of Hope Medical Center · Duarte, California and 1 other locations · NCT07128680

• Aromatherapy with peppermint, lavender, or ginger to ease anxiety and nausea during outpatient chemotherapy infusions

  This research will test whether inhaling peppermint, ginger, or lavender essential oils can reduce nausea and anxiety for adults getting outpatient chemotherapy infusions.

  Recruiting at 2 sites City of Hope Medical Center · Duarte, California and 1 other locations · NCT07126301

• Comparing two blood tests to find colorectal cancer coming back after surgery

  This tests whether the Haystack blood test finds returning colorectal cancer earlier than the Signatera test in adults who have had curative surgery for stage II–IV disease.

  Recruiting at 13 sites City of Hope Medical Center · Goodyear, Arizona and 12 other locations · NCT07125729

• Low-dose ATG followed by adalimumab or verapamil for people with recent-onset type 1 diabetes

  This trial will test whether a short course of low-dose anti-thymocyte globulin (ATG) followed by either adalimumab or verapamil can help preserve insulin production in people aged 9 to under 21 with recent-onset type 1 diabetes.

  Recruiting at 10 sites Phase 1/2 City of Hope Medical Center · Los Angeles, California and 10 other locations · NCT07061574

• Fecal transplant to restore gut microbiome before CAR T therapy for relapsed or refractory B‑cell lymphoma

  This trial will test whether a fecal microbiome transplant can restore healthy gut bacteria and improve outcomes for adults with relapsed or refractory CD19 B‑cell lymphoma who received high‑risk antibiotics and are receiving CAR T‑cell therapy.

  Recruiting Phase 2 City of Hope Medical Center · Duarte, California · NCT07042438

• Asciminib as maintenance after cellular therapies for Ph+ ALL

  This phase 1 study tests whether maintenance with asciminib is safe and tolerable for adults with Philadelphia chromosome–positive ALL after HSCT or CAR-T therapy.

  Recruiting Phase 1 City of Hope Medical Center · Duarte, California · NCT07040982

• Adding CBM588 to pembrolizumab after surgery for kidney cancer

  This trial tests whether adding CBM588 to pembrolizumab after kidney cancer surgery helps prevent recurrence compared with pembrolizumab alone.

  Recruiting at 2 sites Phase 2 City of Hope Medical Center · Duarte, California and 1 other locations · NCT07037004

• MiRisten to treat relapsed or refractory acute myeloid leukemia

  This phase 1 trial tests whether intravenous miRisten, a miR-126 inhibitor, is safe and tolerable and may help adults with relapsed or refractory acute myeloid leukemia.

  Recruiting Phase 1 City of Hope Medical Center · Duarte, California · NCT07025564

• Biomarker-guided ruxolitinib to prevent chronic graft-versus-host disease after allogeneic stem cell transplant

  This study tests whether giving ruxolitinib based on blood GVHD biomarkers around day 100 after an allogeneic stem cell transplant can prevent chronic GVHD in adults at higher biomarker risk.

  Recruiting Phase 1 City of Hope Medical Center · Duarte, California · NCT07025538

• CMV Triplex vaccine to boost immunity and prevent CMV after haploidentical stem cell transplant

  This trial tests whether giving a CMV-MVA Triplex vaccine to donors and/or recipients, with or without the antiviral letermovir, can boost CMV immunity and prevent CMV viremia in people having haploidentical stem cell transplants.

  Recruiting at 3 sites Phase 1 City of Hope Medical Center · Duarte, California and 2 other locations · NCT07020533

• Mogamulizumab-associated rash in people with mycosis fungoides or Sézary syndrome

  See if a rash that appears while taking mogamulizumab is a drug-related rash and how it links to treatment response in adults with relapsed or refractory mycosis fungoides or Sézary syndrome.

  Recruiting at 2 sites City of Hope Medical Center · Duarte, California and 9 other locations · NCT07003100

• Adding emapalumab to standard post-transplant medicines to prevent graft‑versus‑host disease after reduced‑intensity donor stem cell transplant

  This trial will test whether adding emapalumab to post‑transplant cyclophosphamide, tacrolimus, and mycophenolate mofetil can prevent graft‑versus‑host disease in adults with AML or MDS receiving a reduced‑intensity donor stem cell transplant.

  Recruiting Phase 1 City of Hope Medical Center · Duarte, California · NCT06996119

• Using virtual reality to help improve mental health and pain in head and neck cancer patients and their caregivers

  This study is testing if a special virtual reality program can help improve mental health and reduce pain for people with head and neck cancer and their caregivers during treatment.

  Recruiting City of Hope Medical Center · Duarte, California · NCT06985784

• Ultra‑short whole-breast radiation with lumpectomy cavity boost for stage I–III breast cancer

  This trial will test whether a very short course of whole‑breast radiation with a boost to the lumpectomy cavity works well and is safe for women age 40 and older with stage I–III breast cancer who had breast‑conserving surgery.

  Recruiting at 6 sites Phase 2 City of Hope Medical Center · Arcadia, California and 6 other locations · NCT06954831

• Glofitamab after obinutuzumab pre-treatment for central nervous system lymphoma

  This trial will test if giving glofitamab after a short obinutuzumab pre-treatment is safe and helpful for adults with primary or secondary central nervous system lymphoma.

  Recruiting Phase 1 City of Hope Medical Center · Duarte, California · NCT06922604

• Erwinia asparaginase with chemotherapy for high‑risk adults with newly diagnosed Philadelphia‑negative acute lymphoblastic leukemia or lymphoblastic lymphoma

  This trial tries Erwinia-derived asparaginase together with induction and consolidation chemotherapy in adults 18–54 with newly diagnosed high‑risk, Philadelphia chromosome–negative ALL or lymphoblastic lymphoma.

  Recruiting at 4 sites Phase 2 City of Hope Medical Center · Phoenix, Arizona and 7 other locations · NCT06918431

• Photon VMAT craniospinal radiation for leptomeningeal disease from breast or non‑small cell lung cancer

  This trial tests whether craniospinal irradiation delivered with photon VMAT can help adults whose breast cancer or non‑small cell lung cancer has spread to the meninges (leptomeningeal disease).

  Recruiting at 2 sites Phase 2 City of Hope Medical Center · Duarte, California and 1 other locations · NCT06910761

• Cemiplimab plus Y-90 radioembolization for breast cancer that has spread to the liver

  This trial tests whether giving the immunotherapy cemiplimab together with Y-90 liver radioembolization can boost immune attack and shrink tumors in people whose breast cancer has spread mainly to the liver.

  Recruiting Phase 2 City of Hope Medical Center · Duarte, California · NCT06860815

• Zanubrutinib plus sonrotoclax for relapsed or refractory B‑cell non‑Hodgkin lymphoma in underrepresented racial and ethnic groups

  This phase 1 trial tests whether combining zanubrutinib and sonrotoclax can help adults from underrepresented racial and ethnic groups whose B‑cell non‑Hodgkin lymphoma has returned or not responded to prior treatment.

  Recruiting Phase 1 City of Hope Medical Center · Duarte, California · NCT06859008

• Papaverine combined with radiation therapy for advanced rectal cancer

  This study is testing if adding papaverine to radiation therapy can help people with advanced rectal cancer feel better and improve their treatment results.

  Recruiting Phase 1 City of Hope Medical Center · Duarte, California · NCT06834126

• Using genetically modified immune cells to treat recurrent brain tumors

  This study is testing a new treatment using modified immune cells to see if it can help people with recurring brain tumors feel better and fight their cancer.

  Recruiting Phase 1 City of Hope Medical Center · Duarte, California · NCT06815029

• Vedolizumab with post-transplant cyclophosphamide and short-course tacrolimus to prevent graft-versus-host disease after reduced-intensity allogeneic stem cell transplant

  This trial tests whether adding vedolizumab to post-transplant cyclophosphamide and a short course of tacrolimus can prevent graft-versus-host disease in adults getting reduced-intensity allogeneic stem cell transplants for leukemias or related blood disorders.

  Recruiting Phase 2 City of Hope Medical Center · Duarte, California · NCT06815003

• Neoadjuvant FOLFOX with botensilimab and balstilimab for localized rectal cancer

  This test tries whether giving FOLFOX chemotherapy together with the immune drugs botensilimab and balstilimab before surgery helps people with localized rectal cancer achieve a complete clinical response.

  Recruiting Phase 2 City of Hope Medical Center · Duarte, California · NCT06780787

• AOH1996 in relapsed/refractory AML: finding a safe dose

  This early-phase study tests whether AOH1996 can be given safely to adults with relapsed or refractory AML and what dose works best.

  Recruiting Phase 1 City of Hope Medical Center · Duarte, California · NCT06763341

• Using metformin to treat insulin resistance in women with early-stage breast cancer after chemotherapy

  This study is testing if metformin can help women with early-stage breast cancer who have finished chemotherapy and are struggling with insulin resistance to improve their health.

  Recruiting Phase 3 City of Hope Medical Center · Duarte, California and 2 other locations · NCT06763328

• Using CMV-specific CAR T cells and a vaccine to treat high-risk acute lymphoblastic leukemia after stem cell transplant

  This study is testing a new treatment using special immune cells and a vaccine to see if it can help people with high-risk acute lymphoblastic leukemia after they have a stem cell transplant.

  Recruiting Early Phase 1 City of Hope Medical Center · Duarte, California · NCT06735690

• Zanubrutinib with odronextamab for Richter's transformation

  This phase I test will see if combining zanubrutinib with odronextamab helps adults whose chronic lymphocytic leukemia has transformed into aggressive lymphoma (Richter's transformation).

  Recruiting Phase 1 City of Hope Medical Center · Duarte, California · NCT06735664

• Phytocannabinoids to reduce chronic chemotherapy-related nerve pain in breast and colon cancer survivors

  This will test whether daily CBD or a combined THC:CBD treatment can reduce long-term nerve pain, tingling, and numbness in people who survived breast or colon cancer.

  Recruiting at 2 sites Phase 2 City of Hope Medical Center · Duarte, California and 1 other locations · NCT06731894

• Nab‑paclitaxel PIPAC with paclitaxel and ramucirumab for stomach cancer that has spread to the peritoneum

  This phase I trial tests whether giving nab‑paclitaxel as a pressurized intraperitoneal aerosol (PIPAC) together with systemic paclitaxel and ramucirumab is safe and can help adults whose stomach cancer has spread to the peritoneal lining after first‑line therapy.

  Recruiting Phase 1 City of Hope Medical Center · Duarte, California · NCT06675136

• Pacritinib combined with a BTK inhibitor for relapsed or refractory mantle cell lymphoma

  This study tests whether adding pacritinib to a BTK inhibitor is safe and can help adults whose mantle cell lymphoma has returned or not responded to prior treatments.

  Recruiting Phase 1 City of Hope Medical Center · Duarte, California · NCT06675123

• Using revumenib to treat acute leukemia after stem cell transplant

  This study is testing a new drug called revumenib to see if it can help people with acute leukemia feel better after they’ve had a stem cell transplant.

  Recruiting Phase 1 City of Hope Medical Center · Duarte, California · NCT06575296

• Combining nemtabrutinib and rituximab to treat mantle cell lymphoma

  This study is testing if combining two treatments, nemtabrutinib and rituximab, can help people with newly diagnosed mantle cell lymphoma feel better and live longer.

  Recruiting Phase 2 City of Hope Medical Center · Duarte, California and 1 other locations · NCT06572618

• Biology-guided radiation therapy for painful bone metastases

  This study is testing a new type of radiation therapy to see if it can help people with painful bone cancer feel less pain and improve their quality of life.

  Recruiting Phase 1 City of Hope Medical Center · Duarte, California · NCT06549478

• Using olutasidenib to prevent relapse in patients with IDH1 mutated blood cancers after transplant

  This study is testing if a new drug called olutasidenib can help prevent blood cancers from coming back in patients with a specific gene mutation after they have had a stem cell transplant.

  Recruiting Phase 1 City of Hope Medical Center · Duarte, California and 1 other locations · NCT06543381

• Telehealth support for managing ostomies in cancer patients

  This study is testing a telehealth program to help people with colorectal and bladder cancer manage their ostomies better before and after surgery.

  Recruiting Phase 2 City of Hope Medical Center · Duarte, California · NCT06528990

• Telehealth coaching to improve life quality for pancreatic cancer survivors and their caregivers

  This study tests whether telehealth coaching can help improve the quality of life for people surviving pancreatic cancer and their caregivers.

  Recruiting City of Hope Medical Center · Arcadia, California and 21 other locations · NCT06524973

• Using denosumab to improve beta cell function in type 1 diabetes

  This study is testing if a medication called denosumab can help improve insulin production and blood sugar control in people with early type 1 diabetes.

  Recruiting at 3 sites Phase 1/2 City of Hope Medical Center · Birmingham, Alabama and 2 other locations · NCT06524960

• Using tagraxofusp and azacitidine to prevent cancer recurrence after transplant in certain leukemia and syndrome patients

  This study is testing if a new combination of two drugs can help prevent cancer from coming back in people with certain types of leukemia and blood disorders after they have had a stem cell transplant.

  Recruiting Phase 1 City of Hope Medical Center · Duarte, California · NCT06498973

• Predicting nerve damage from chemotherapy in gastric cancer patients

  This study is testing a new blood test to see if it can help predict which gastric cancer patients are at risk of nerve damage from chemotherapy, so doctors can tailor their treatment accordingly.

  Recruiting City of Hope Medical Center · Kurashiki, Okayama-ken · NCT06490159

• Predicting how well chemotherapy will work for esophageal cancer patients

  This study is testing if DNA changes in biopsy samples can help doctors predict how well chemotherapy will work for patients with esophageal cancer, so those who might not benefit can avoid unnecessary treatment.

  Recruiting City of Hope Medical Center · Chūō, Yamanashi · NCT06490003

• Predicting early tumor recurrence in esophageal cancer patients

  This study is testing if certain DNA patterns from tissue samples can help predict if esophageal cancer will come back early in patients who have had surgery.

  Recruiting at 2 sites City of Hope Medical Center · Nagoya, Aichi-ken and 1 other locations · NCT06476067

• Treatment for relapsed or refractory follicular lymphoma using two monoclonal antibodies

  This study is testing a combination of two new treatments for people with follicular lymphoma that hasn't responded to previous therapies to see if they can improve their health and survival.

  Recruiting Phase 2 City of Hope Medical Center · Duarte, California and 1 other locations · NCT06453044

• Treatment for high-risk thyroid cancer with BRAF mutation

  This study is testing if a combination of two medications can help people with high-risk thyroid cancer that has a specific mutation feel better before they receive radioactive iodine treatment.

  Recruiting Phase 2 City of Hope Medical Center · Duarte, California · NCT06440850

• Evaluating risk factors for stomach cancer

  This study is testing different ways to find out if people aged 40 to 80 from racial minority groups are at high risk for stomach cancer to help catch it early.

  Recruiting City of Hope Medical Center · Duarte, California · NCT06408220

• Early detection of pancreatic cancer using exosome-based biomarkers

  This study is testing a new way to find pancreatic cancer early by looking at tiny particles in the blood that carry specific markers.

  Recruiting at 11 sites City of Hope Medical Center · Phoenix, Arizona and 12 other locations · NCT06388967

• Blood test for early detection of colorectal cancer and adenomas

  This study is testing a new blood test to see if it can help find early signs of colorectal cancer and adenomas in people who are already scheduled for a colonoscopy.

  Recruiting at 6 sites City of Hope Medical Center · Monrovia, California and 5 other locations · NCT06342440

• Liquid biopsy to differentiate types of primary liver cancer

  This study is testing a new blood test to see if it can tell the difference between two types of liver cancer, hepatocellular carcinoma and intrahepatic cholangiocarcinoma, to help doctors diagnose patients more safely.

  Recruiting at 5 sites City of Hope Medical Center · Duarte, California and 4 other locations · NCT06342414

• Detecting early onset colorectal cancer using a blood test

  This study is testing a new blood test that looks for specific markers to help find early signs of colorectal cancer in young adults.

  Recruiting at 13 sites City of Hope Medical Center · Duarte, California and 12 other locations · NCT06342401

• Predicting recurrence in stage II/III colorectal cancer after chemotherapy

  This study is trying to create a test that can help predict if people with stage II/III colorectal cancer will have their cancer come back after chemotherapy.

  Recruiting at 4 sites City of Hope Medical Center · Monrovia, California and 3 other locations · NCT06314958

• Using a new antibody treatment with chemotherapy and radiation for high-risk blood cancers before stem cell transplant

  This study is testing a new antibody treatment combined with chemotherapy and radiation to see if it can help people with high-risk blood cancers before they receive a stem cell transplant.

  Recruiting Phase 1 City of Hope Medical Center · Duarte, California · NCT06287944

• Using targeted radiation therapy for treating specific metastatic breast cancer cases

  This study is testing if a targeted radiation treatment can help people with certain types of metastatic breast cancer keep taking their regular medication for at least 24 weeks while also checking how it affects their safety and quality of life.

  Recruiting at 2 sites Phase 2 City of Hope Medical Center · Duarte, California and 1 other locations · NCT06260033

• Using CMV-specific T cells to treat HIV/AIDS

  This study is testing a new treatment using specially designed T cells to see if they can help people with HIV live better while they are on their regular medication.

  Recruiting at 2 sites Early Phase 1 City of Hope Medical Center · Duarte, California and 1 other locations · NCT06252402

• Combining carfilzomib and sotorasib for treating advanced lung cancer with KRAS G12C mutation

  This study is testing a new combination of two drugs, carfilzomib and sotorasib, to see if it can safely help people with advanced lung cancer that has a specific KRAS G12C mutation after they have tried other treatments.

  Recruiting at 2 sites Phase 1 City of Hope Medical Center · Duarte, California and 1 other locations · NCT06249282

• Coaching or self-monitoring to improve physical function in older lung cancer surgery patients and their caregivers

  This study is testing whether phone coaching or self-monitoring can help older lung cancer surgery patients and their caregivers improve their physical function after surgery.

  Recruiting at 16 sites City of Hope Medical Center · Davis, California and 15 other locations · NCT06196008

• Evaluating geriatric assessments for older adults with lung cancer undergoing treatment

  This study tests if using special health assessments for older adults with lung cancer can help them handle treatment better and improve their quality of life.

  Recruiting at 2 sites City of Hope Medical Center · Duarte, California and 2 other locations · NCT06139627

• Activating the immune response to treat advanced colorectal and breast cancer

  This study is testing a new immune treatment combined with radiation to see if it can help people with advanced colorectal or breast cancer that can't be surgically removed.

  Recruiting Phase 1 City of Hope Medical Center · Duarte, California · NCT06130826

• Using ruxolitinib, tacrolimus, and methotrexate to prevent graft versus host disease in young patients after bone marrow transplant

  This study is testing if a combination of three medications can help prevent graft versus host disease in young patients after they receive a bone marrow transplant for certain types of leukemia or blood disorders.

  Recruiting Phase 2 City of Hope Medical Center · Duarte, California · NCT06128070

• Vaccination to prevent CMV infection in stem cell transplant patients

  This study is testing a new vaccine to see if it can help prevent CMV infections in patients receiving stem cell transplants from related donors.

  Recruiting at 3 sites Phase 2 City of Hope Medical Center · Duarte, California and 2 other locations · NCT06059391

• Combination therapy for relapsed or refractory mantle cell lymphoma

  This study is testing a new combination of three drugs to see if it can help people with mantle cell lymphoma that hasn't responded to previous treatments.

  Recruiting Phase 2 City of Hope Medical Center · Duarte, California · NCT06054776

• Geriatric assessment to improve recovery after CAR-T therapy for older patients with blood cancers

  This study is testing if personalized support and therapy can help older patients with blood cancers recover better after receiving CAR-T treatment.

  Recruiting at 4 sites Phase 2 City of Hope Medical Center · Duarte, California and 3 other locations · NCT06052826

• Dose-reduced chemotherapy for older women with early-stage HER2 negative breast cancer

  This study is testing if a lower dose of chemotherapy can help older women with early-stage HER2 negative breast cancer feel better during treatment compared to the standard dose.

  Recruiting at 3 sites Phase 2 City of Hope Medical Center · Duarte, California and 2 other locations · NCT06042569

• Telemedicine support for older cancer patients in underserved communities

  This study tests whether using telemedicine to provide extra support can help older cancer patients in underserved communities feel better and have fewer hospital visits compared to standard care.

  Recruiting at 3 sites City of Hope Medical Center · Duarte, California and 2 other locations · NCT06022965

• Combining advanced radiation therapy with a targeted drug for specific lung cancer patients

  This study is testing whether combining advanced radiation therapy with the drug osimertinib can help people with specific types of lung cancer control their disease better and improve their quality of life.

  Recruiting Phase 2 City of Hope Medical Center · Duarte, California and 1 other locations · NCT06014827

• Using bright white light therapy to reduce fatigue and depression in advanced prostate cancer patients

  This study is testing if bright white light therapy can help reduce fatigue and depression in men with advanced prostate cancer who are receiving treatment.

  Recruiting Phase 2 City of Hope Medical Center · Duarte, California · NCT05869682

• Combination treatment for newly diagnosed high-risk mantle cell lymphoma

  This study is testing a new combination of treatments for people with newly diagnosed high-risk mantle cell lymphoma to see if it helps them live longer without the disease getting worse.

  Recruiting at 3 sites Phase 1/2 City of Hope Medical Center · Duarte, California and 2 other locations · NCT05861050

• Using PET scans to guide targeted radiation therapy for certain cancers

  This study is testing if using PET scans to guide targeted radiation therapy can help people with certain cancers, like lung cancer and melanoma, get better results than standard treatment.

  Recruiting at 2 sites Phase 2 City of Hope Medical Center · Duarte, California and 1 other locations · NCT05830058

• CAR-T cell therapy with or without radiation for advanced prostate cancer

  This study is testing if a new CAR-T cell therapy, with or without radiation, can help people with advanced prostate cancer live longer and feel better.

  Recruiting Phase 1 City of Hope Medical Center · Duarte, California · NCT05805371

• Treatment using genetically modified T-cells and a vaccine for B-Cell Non-Hodgkin Lymphoma

  This study is testing a new treatment that uses specially modified immune cells and a vaccine to see if it can help people with tough-to-treat B-cell non-Hodgkin lymphoma feel better.

  Recruiting Phase 1 City of Hope Medical Center · Duarte, California · NCT05801913

• Bridging radiation therapy before CAR T-cell infusion for large B-cell lymphoma

  This study is testing whether giving radiation therapy before CAR T-cell treatment can help people with relapsed or hard-to-treat large B-cell lymphoma feel better and have better outcomes.

  Recruiting Early Phase 1 City of Hope Medical Center · Duarte, California · NCT05800405

• Improving genetic counseling for at-risk relatives of cancer patients

  This study is testing if talking directly with a healthcare provider about genetic testing results can help at-risk family members of cancer patients get tested more often and feel better about it.

  Recruiting City of Hope Medical Center · Duarte, California · NCT05772130

• Reduced-intensity treatment followed by stem cell transplant for severe aplastic anemia

  This study is testing a gentler treatment before a stem cell transplant to see if it can safely help people with severe aplastic anemia who haven't responded to other treatments.

  Recruiting Phase 1 City of Hope Medical Center · Duarte, California · NCT05757310

• Effects of exercise therapy on prostate cancer indicators

  This study is testing if a home-based walking program can help men with low-risk prostate cancer show better signs of their condition compared to those who stick to their usual exercise routines.

  Recruiting Phase 2 City of Hope Medical Center · Duarte, California and 9 other locations · NCT05751434

• Using advanced radiation therapy to treat patients with multiple metastatic tumors

  This study is testing a new type of targeted radiation therapy to see if it can safely help patients with multiple tumors feel better while protecting healthy tissue.

  Recruiting Early Phase 1 City of Hope Medical Center · Duarte, California · NCT05733949

• Using a robotic system for less invasive abdominal and pelvic surgeries

  This study is testing a new robotic system for abdominal and pelvic surgeries to see if it can make recovery easier and safer for patients compared to traditional surgery methods.

  Recruiting Phase 2 City of Hope Medical Center · Duarte, California · NCT05672368

• Treatment for relapsed or refractory diffuse large B-cell lymphoma

  This study is testing a new combination of two treatments for people with relapsed or hard-to-treat diffuse large B-cell lymphoma to see if it helps them respond better and live longer.

  Recruiting Phase 2 City of Hope Medical Center · Duarte, California · NCT05672251

• CAR T Cell Therapy for Recurrent or Refractory Acute Myeloid Leukemia

  This study is testing a new CAR T-cell therapy to see if it can help people with recurring or hard-to-treat acute myeloid leukemia by using modified immune cells to attack cancer cells.

  Recruiting Phase 1 City of Hope Medical Center · Duarte, California · NCT05672147

• Treatment for lung cancer using targeted chemotherapy delivery

  This study is testing a new way to deliver chemotherapy directly to lung tumors in patients with hard-to-treat lung cancer to see if it helps control tumor growth better than standard treatments.

  Recruiting at 2 sites Phase 2 City of Hope Medical Center · Duarte, California and 1 other locations · NCT05672108

• Treatment of primary central nervous system lymphoma using modified T cells delivered into the brain

  This study is testing if giving special immune cells directly into the brain can help people with primary central nervous system lymphoma fight their cancer.

  Recruiting Phase 1 City of Hope Medical Center · Duarte, California · NCT05625594

• Using light and occupational therapy to manage fatigue in cancer patients

  This study is testing if combining light therapy with occupational therapy can help cancer patients with genitourinary cancers feel less tired and improve their daily activities.

  Recruiting City of Hope Medical Center · Duarte, California · NCT05519878

• Understanding biomarkers in the development of Type 1 diabetes

  This study is trying to see how certain biological markers in blood, saliva, and urine can help us understand and possibly spot Type 1 diabetes earlier in people who have it or are at risk.

  Recruiting City of Hope Medical Center · Duarte, California · NCT05505669

• Using leflunomide with steroids to treat acute graft-versus-host disease after stem cell transplant

  This study is testing if adding leflunomide to steroid treatment can help people with acute graft-versus-host disease after a stem cell transplant feel better and reduce their symptoms.

  Recruiting Phase 1 City of Hope Medical Center · Duarte, California · NCT05443425

• Using genetically modified T-cells and a vaccine to treat certain types of B-cell lymphoma after stem cell transplantation

  This study is testing a new treatment using specially modified immune cells and a vaccine to see if it can help people with certain types of B-cell lymphoma after they've had a stem cell transplant.

  Recruiting Phase 1 City of Hope Medical Center · Duarte, California · NCT05432635

• Imaging HER2+ Breast Cancer with Brain Metastasis using a New Scan

  This study is testing a new type of scan to see if it can help doctors better understand how well a treatment works for people with HER2+ breast cancer that has spread to the brain.

  Recruiting Phase 4 City of Hope Medical Center · Duarte, California · NCT05376878

• Evaluating CD8 PET Imaging for Immune Response in Cancer Treatment

  This study is testing if a special type of radiation therapy can boost immune cells in patients with lymphoma and solid tumors, while also checking if a new imaging method can safely track these changes.

  Recruiting Phase 1 City of Hope Medical Center · Duarte, California · NCT05371132

• Daratumumab with indium‑111 and actinium‑225 radioimmunotherapy for relapsed or refractory multiple myeloma

  This trial will see if combining daratumumab with indium‑111 and actinium‑225 labeled daratumumab is safe and may help adults whose multiple myeloma has returned or stopped responding to prior treatments.

  Recruiting Phase 1 City of Hope Medical Center · Duarte, California · NCT05363111

• Aerosolized chemotherapy for biliary tract cancer with peritoneal metastases

  This study is testing a new way to deliver chemotherapy directly into the abdomen for patients with biliary tract cancer that has spread to see if it helps them live longer and feel better.

  Recruiting Phase 1 City of Hope Medical Center · Duarte, California · NCT05285358

• Evaluating DNA Methylation for Diagnosing Thyroid Nodules

  This study is testing a new DNA test to see if it can help doctors tell the difference between cancerous and non-cancerous thyroid nodules to reduce unnecessary surgeries.

  Recruiting City of Hope Medical Center · Duarte, California · NCT05229341

• Using AOH1996 to treat hard-to-treat solid tumors

  This study is testing a new drug called AOH1996 to see if it is safe and effective for people with hard-to-treat solid tumors like certain sarcomas and ovarian cancer.

  Recruiting at 2 sites Phase 1 City of Hope Medical Center · Scottsdale, Arizona and 2 other locations · NCT05227326

• Using modified immune cells to treat platinum-resistant ovarian cancer

  This study is testing whether modified immune cells can help people with platinum-resistant ovarian cancer fight their tumors.

  Recruiting Phase 1 City of Hope Medical Center · Duarte, California · NCT05225363

• Treatment of advanced cancer using a targeted radioactive antibody

  This study is testing a new radioactive treatment for advanced colorectal cancer to see how safe it is and what the best dose is for patients.

  Recruiting Phase 1 City of Hope Medical Center · Duarte, California · NCT05204147

• Using neural stem cells with a virus to treat recurrent high-grade brain tumors

  This study is testing a new treatment using neural stem cells and a virus to see if it can help people with recurrent high-grade brain tumors feel better and live longer.

  Recruiting at 2 sites Phase 1 City of Hope Medical Center · Duarte, California and 3 other locations · NCT05139056

• Treatment for erythrodermic cutaneous T cell lymphoma using photopheresis and mogamulizumab

  This study is testing a new treatment combining light therapy and a medication for people with a rare skin cancer called erythrodermic cutaneous T cell lymphoma to see if it helps them feel better and improves their quality of life.

  Recruiting Phase 2 City of Hope Medical Center · Scottsdale, Arizona and 2 other locations · NCT04930653

• Effects of white button mushroom on inflammation in obese postmenopausal women at high risk of breast cancer

  This study is testing if eating white button mushrooms every day for three months can help reduce inflammation and improve immune health in obese postmenopausal women who are at high risk for breast cancer.

  Recruiting City of Hope Medical Center · Duarte, California · NCT04913064

• Treatment for recurrent or refractory Hodgkin lymphoma using a combination of targeted therapy and chemotherapy

  This study is testing a new combination of targeted therapy and chemotherapy to see if it can help people with recurring or stubborn Hodgkin lymphoma before they undergo a stem cell transplant.

  Recruiting Phase 2 City of Hope Medical Center · Duarte, California · NCT04871607

• Detecting changes in gut and urinary microbiome during prostate cancer treatment

  This study is trying to see how treatment for prostate cancer affects the bacteria in the gut and urine of patients to understand if these changes relate to side effects from the therapy.

  Recruiting City of Hope Medical Center · Duarte, California · NCT04775355

• Combining talazoparib with hormone therapy and abiraterone for prostate cancer treatment

  This study is testing if adding a new drug called talazoparib to standard hormone therapy and abiraterone can help men with advanced prostate cancer do better with their treatment.

  Recruiting Phase 2 City of Hope Medical Center · Duarte, California · NCT04734730

• Assessing quality of life in patients with cutaneous lymphoma

  This study looks at how living with cutaneous lymphoma affects adults' quality of life and what support they might need to feel better.

  Recruiting City of Hope Medical Center · Duarte, California · NCT04670874

• Exploring how exercise affects cancer recurrence

  This study is testing how different levels of aerobic exercise can help reduce the chances of cancer coming back in people who have been treated for breast, prostate, or colorectal cancer.

  Recruiting City of Hope Medical Center · Durate, California and 8 other locations · NCT04589468

• Treatment for relapsed or refractory classical Hodgkin lymphoma using brentuximab vedotin and nivolumab

  This study is testing a combination of two drugs, brentuximab vedotin and nivolumab, to see if they can help people with classical Hodgkin lymphoma that has come back or didn’t respond to previous treatments.

  Recruiting at 5 sites Phase 2 City of Hope Medical Center · Duarte, California and 4 other locations · NCT04561206

• Using CAR T cells after chemotherapy to treat recurrent brain tumors in children

  This study is testing a new treatment for children with recurring brain tumors by combining chemotherapy with special immune cells to see if it helps them live longer and feel better.

  Recruiting at 3 sites Phase 1 City of Hope Medical Center · Duarte, California and 2 other locations · NCT04510051

Showing recruiting studies first, then the newest. Describe your situation to find the ones that fit you.

Quick answers

How many clinical trials run by City of Hope Medical Center are recruiting right now?

159, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 10 countries. The most sites are in United States (156 trials), Japan (7 trials), Spain (3 trials), China (2 trials), Italy (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 44, Phase 1: 44, Phase 1/2: 8, Early Phase 1: 5. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →