Clinical trial Recruiting at 1 site Observational Ages 18 and up

Couples Coping Together Against Cancer: A Feasibility and Acceptability Look

Official title: Investigating the Feasibility and Acceptability of an Innovative Interdisciplinary Supportive Care Program: Couples Coping Together Against Cancer

Run by City of Hope Medical Center · NCT07664579 · Data updated 2026-11-12

This observational study tests whether a brokered program for patients with cancer and their partners is feasible and acceptable, and whether it may reduce distress over time.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment160 (estimated)
SponsorCity of Hope Medical Center
Academic / other
Locations1 site (Duarte, California)
StatusRecruiting
StartedJuly 5, 2024
Main results expectedJanuary 4, 2027
Study endsJanuary 4, 2027
Registry record updatedNovember 9, 2026
Trial IDNCT07664579 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults with glioblastoma or other cancers who are new to City of Hope or receive care there, are in a relationship, speak English or Spanish, and have access to the internet.

Probably not a fit

Participants with severe cognitive impairment or other conditions preventing study procedures may not benefit and could be excluded.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study enrolls patients with cancer and their partners who are treated at City of Hope and uses the Connecting Care App to deliver biopsychosocial screening and psychoeducation sessions. Participants may also receive up to four counseling sessions, each 30–45 minutes, with surveys completed throughout the study. The primary goals are to determine the feasibility and acceptability of the program components, while an exploratory objective looks for signals of reduced biopsychosocial distress in patients and partners over time. The program is non-interventional and focuses on integrating patient-partner support within standard care. The study includes adults who speak English or Spanish, have a compatible tech setup, and are in a committed relationship with a participating partner.

Why it matters

Potential benefit: If successful, the program could improve coping and reduce distress for patients and their partners.

How similar studies have gone: Prior work in psychosocial support for cancer couples has shown potential benefits in coping, though this exact program is exploratory and observational in nature.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Have received a diagnosis of a primary brain tumor (glioblastoma), or other cancers (breast, lung, etc.)
* Are new patients to City of Hope (COH) (all sites) or receive at least some of their care at City of Hope- Duarte Campus (care is defined as: procedures, consults, laboratories, imaging, surgery, and/or treatment)
* The patient is in a committed relationship/partnership with a partner and the partner is available and willing to participate
* Are English or Spanish speaking
* ≥ 18 years of age
* Have access to a smartphone, computer/laptop or internet connection to complete all study procedures

Exclusion Criteria:

* Significant cognitive impairment
* Inpatient psychiatric treatment for severe mental illness or overt signs of severe psychopathology (e.g., psychosis)
* Visual, hearing, voice, or motor impairment that prevents completion of study procedures as evidenced by clinical judgment
* Committed partners will be excluded from the study if they:

  * Refuse to complete informed consent
  * Have cognitive impairment
  * Have severe mental illness that would prevent informed consent and completion of study activities as evidenced by clinical judgment

Where it's running

  • City of Hope Medical Center
    Duarte, California, United States
    Recruiting

Study contacts

  • Principal investigator: William Dale — City of Hope Medical Center

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.