Evaluating risk factors for stomach cancer
OUR Stomach Health Project: A Pilot Study to Evaluate the Feasibility of Stomach Cancer Risk Assessment for Early Detection and Secondary Prevention
This study is testing different ways to find out if people aged 40 to 80 from racial minority groups are at high risk for stomach cancer to help catch it early.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 240 (estimated) |
| Ages | 40 Years to 80 Years |
| Sex | All |
| Sponsor | City of Hope Medical Center Academic / other |
| Locations | 1 site (Duarte, California) |
| Trial ID | NCT06408220 on ClinicalTrials.gov |
What this trial studies
This clinical trial assesses the effectiveness of various risk assessment methods, including H. pylori breath tests, questionnaires, and endoscopies, to identify individuals at high risk for gastric carcinoma. Participants aged 40 to 80 who identify as racial minorities will undergo these assessments to determine their risk levels. Those identified as high-risk may receive further evaluations, including upper endoscopies, to check for potential gastric cancer. The study aims to enhance early detection and understanding of gastric cancer risk factors in diverse populations.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals aged 40 to 80 who identify as Asian, Hispanic, or Black American.
Not a fit: Patients who are non-Hispanic White or have a history of gastric cancer may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to earlier detection and improved outcomes for patients at high risk for stomach cancer.
How similar studies have performed: Other studies have shown promise in using similar risk assessment approaches for early detection of gastric cancer, indicating potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Documented informed consent of the participant and/or legally authorized representative * Assent, when appropriate, will be obtained per institutional guidelines * Age: ≥ 40 years to ≤ 80 years * Identify as a racial minority either Asian, Hispanic, or Black American * Willingness to: * Provide blood samples and undergo upper endoscopy Exclusion Criteria: * Identify as Non-Hispanic White * History of gastric cancer * Known premalignant lesions of the stomach * History of upper endoscopy within 2 years * Women of childbearing potential: Pregnant/ nursing * An employee who is under the direct/indirect supervision of the principal investigator (PI)/a coinvestigator/the study manager * A direct study team member
Where this trial is running
Duarte, California
- City of Hope Medical Center — Duarte, California, United States (Recruiting)
Study contacts
- Principal investigator: Yanghee Woo — City of Hope Medical Center
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.