Blood test for early detection of colorectal cancer and adenomas

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to develop a highly sensitive and cost-effective blood assay for the early detection of colorectal adenomas and cancer using advanced machine learning techniques and biological analyses. Colorectal cancer is a major health concern, and traditional screening methods often miss precursor lesions like adenomas. The proposed liquid biopsy test seeks to provide a non-invasive alternative that can detect both conditions from a single blood draw, thereby improving patient compliance and resource allocation. Participants will have undergone a colonoscopy, and blood samples will be collected prior to any curative treatment.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* All individuals included in the study need to have had a colonoscopy at the time of blood sampling.
* Received standard diagnostic and staging (as necessary) procedures as per local guidelines, and at least one sample was drawn before receiving any curative-intent treatment.
* Received standard pathological and endoscopic diagnosis and assessment for cohort assignment.

Exclusion Criteria:

* Hereditary colorectal cancer syndromes (identified through genetic testing).
* Inflammatory bowel diseases.
* Lack of written informed consent.

Where it's running

• City of Hope Medical Center
  Monrovia, California, United States Recruiting
• University of California San Diego
  San Diego, California, United States Recruiting
• The First Affiliated Hospital of Dalian Medical University
  Dalian, China Recruiting
• IRCCS San Raffaele
  Milan, Italy Recruiting
• Mie University
  Mie, Japan Recruiting
• Barcelona University
  Barcelona, Spain Recruiting

Study contacts

• Principal investigator: Ajay Goel, PhD — City of Hope Medical Center
• Study coordinator: Ajay Goel, PhD
• Email: AJGOEL@COH.ORG
• Phone: 6262183452

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.