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Clinical trials and research at Children's Hospital of Philadelphia

• 85Clinical trials
• 2New in 30 days
• 20Countries

Newest trials

All recruiting trials (85)

• FaceSay: a computer program to help kids recognize facial expressions and improve social interactions

  A computer-based FaceSay program is tested to see if it helps survivors of pediatric brain tumors who have social difficulties see facial expressions better and relate more comfortably with peers.

  Recruiting Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT07923370

• Physiology-guided Epinephrine Dosing in Pediatric Cardiac Arrest

  This observational study looks at how a child’s body responds to epinephrine during in-hospital cardiac arrests to see if dosing can be guided by physiology.

  Recruiting at 22 sites Children's Hospital of Philadelphia · Orange, California and 21 other locations · NCT07890610

• Observation vs Upfront Surgery for Asymptomatic Kidney Stones in Children and Adults

  This trial tests whether watching asymptomatic kidney stones or performing upfront surgery is better for reducing life disruption in patients aged 6 and older.

  Recruiting at 2 sites Children's Hospital of Philadelphia · Irvine, California and 3 other locations · NCT07718802

• Heartsight helps caregivers of kids after cardiac arrest manage uncertainty and fear

  This pilot trial tests if the Heartsight information program is acceptable and helpful for caregivers of children who recently had a cardiac arrest.

  Recruiting Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT07707037

• BCAAs in Concussion: a higher-dose test in teens and young adults

  This trial will test whether high-dose branched-chain amino acids help teens and young adults recover from concussion compared with a placebo.

  Recruiting Phase 2 Children's Hospital of Philadelphia · Havertown, Pennsylvania · NCT07670195

• LNP.UCD.ABE for severe urea cycle disorders in young children

  This trial tests a single IV dose of LNP.UCD.ABE in five young children with severe urea cycle disorders to see if it is safe and may help reduce ammonia buildup.

  Recruiting Phase 1/2 Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT07667387

• Structured lipid nutrition for people with pancreatic cancer

  Try a structured lipid medical food (Encala) to help people with pancreatic cancer who have trouble absorbing fat.

  Recruiting at 2 sites Children's Hospital of Philadelphia · Philadelphia, Pennsylvania and 1 other locations · NCT07554560

• Trametinib for Ras/MAPK Pathway Vascular Anomalies in Kids and Teens

  This study tests whether trametinib can help children and young people with Ras/MAPK-driven vascular anomalies.

  Recruiting Phase 2 Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT07549646

• Alpelisib for PIK3CA/TIE-2/TEK pathway vascular anomalies

  This study tests whether alpelisib can help children and young adults with specific vascular anomalies driven by PIK3CA/TIE-2/TEK pathways.

  Recruiting Phase 2 Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT07543822

• CART123 Cells With or Without Ruxolitinib for Relapsed/Refractory AML

  This trial tests CART123 cells alone or with ruxolitinib to see if they help kids and young adults with relapsed or treatment‑resistant AML.

  Recruiting Phase 1 Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT07464951

• Urine titin test for Duchenne and Becker muscular dystrophy

  We will test whether a urine test that measures a titin fragment can track muscle injury in people with Duchenne or Becker muscular dystrophy and in healthy volunteers.

  Recruiting Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT07332013

• Diet and wearable monitoring of gut movement in children with IBS

  This project will use a wearable patch, diet recall, and stool and urine samples to see if certain foods, gut movement patterns, or microbes are linked to symptoms in children ages 8–18 with IBS.

  Recruiting Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT07283341

• PRAISE with Coaching to reduce aggression and bullying in 3rd–5th graders

  This program tests whether training school staff, with ongoing coaching, to deliver the PRAISE curriculum reduces aggression and bullying among 3rd–5th graders.

  Recruiting Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT07191782

• Boosting motivation to do everyday living skills

  This project will try three different coaching programs to see if they help 16- to 25-year-old autistic teens and young adults feel more motivated and do everyday living tasks more often.

  Recruiting Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT07159308

• Using a supraglottic airway to help newborns breathe at birth

  This project will test whether teaching and equipping delivery teams to use a supraglottic airway helps newborns who need breathing support get effective ventilation sooner.

  Recruiting at 13 sites Children's Hospital of Philadelphia · Birmingham, Alabama and 29 other locations · NCT07150923

• Re-engaging adolescent and young adult cancer survivors in long-term follow-up care

  This project tests whether brief digital messages and written materials help adolescent and young adult cancer survivors re-engage with long-term follow-up care.

  Recruiting at 3 sites Children's Hospital of Philadelphia · Columbus, Ohio and 2 other locations · NCT07138040

• Boosting use of SMART inhaler therapy for children with moderate-to-severe asthma

  This project will test whether adding community health workers and nurse care managers to electronic health record decision support and education helps children ages 5–18 with uncontrolled asthma use single maintenance and reliever therapy (SMART).

  Recruiting Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT07138027

• Implementing SMART asthma care in pediatric primary clinics

  This project will test whether electronic medical record decision support plus clinician education helps pediatric clinics adopt SMART single maintenance and reliever inhaler therapy for children ages 5–18 with uncontrolled asthma.

  Recruiting Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT07137923

• Best breathing strategy during pediatric cardiac arrest

  This study will test whether the OPTI-VENT bundle of breathing adjustments during CPR helps children who have a cardiac arrest in the hospital survive to discharge with good brain function.

  Recruiting at 20 sites Children's Hospital of Philadelphia · Orange, California and 19 other locations · NCT07114510

• Personalized vancomycin dosing to lower kidney injury risk in children with sepsis

  This will test whether using updated, personalized kidney-function markers to guide vancomycin dosing helps children with sepsis reach effective drug levels and reduces kidney injury.

  Recruiting Phase 1 Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT07084129

• Using anti-CD7 CAR-T cells to treat relapsed or refractory T-Cell leukemia or lymphoma

  This study is testing a new CAR-T cell therapy called BEAM-201 to see if it can help young people with tough-to-treat T-Cell leukemia or lymphoma feel better and achieve remission.

  Recruiting Phase 1 Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT06934382

• Improving fitness for adolescents with the Fontan circulation

  This study will test whether a home-based digital exercise program helps 10–17-year-olds with the Fontan circulation become more active and improve fitness compared with enhanced usual care.

  Recruiting Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT06918795

• Impact of massage therapy on sleep in young cancer patients

  This study is testing whether personalized massage therapy can help young cancer patients in the hospital sleep better and feel less tired, anxious, and in pain during their treatment.

  Recruiting Children's Hospital of Philadelphia · Washington D.C., District of Columbia and 1 other locations · NCT06892158

• Understanding brain chemistry in patients with primary mitochondrial disease

  This study is trying to see if measuring certain brain chemicals can help doctors better understand and treat people with primary mitochondrial disease.

  Recruiting Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT06890520

• Fetal treatment for congenital diaphragmatic hernia

  This study is testing a new way to treat congenital diaphragmatic hernia in unborn babies by placing a balloon in their airway to help their lungs grow before they are born.

  Recruiting Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT06884423

• CART19 treatment for lupus in young patients

  This study is testing a new treatment called CART19 to see if it can help young people aged 12-29 with tough-to-treat lupus feel better and improve their health.

  Recruiting Phase 1/2 Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT06839976

• Using CD45RA Depleted Stem Cells to Prevent Infections After Transplant

  This study is testing whether using special stem cells can help patients with high-risk leukemia recover their immune system faster and prevent infections after a stem cell transplant.

  Recruiting Phase 1/2 Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT06839456

• Measuring oxygen levels in muscle tissue using a nanosensor

  This study is testing a tiny sensor to see if it can accurately measure oxygen levels in the muscles of people with mitochondrial myopathy and healthy volunteers during exercise.

  Recruiting Phase 1 Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT06819683

• Reducing vancomycin use in newborn intensive care

  This trial tests whether giving outside support to Level III NICUs helps staff follow vancomycin-reduction practices for newborns at risk of late-onset sepsis.

  Recruiting at 13 sites Children's Hospital of Philadelphia · Modesto, California and 12 other locations · NCT06772675

• Using PEEL-224 with Vincristine and Temozolomide for Pediatric Solid Tumors

  This study is testing a new treatment called PEEL-224, alone and with other drugs, to see if it can help children with tough-to-treat solid tumors like neuroblastoma and rhabdomyosarcoma.

  Recruiting at 7 sites Phase 1/2 Children's Hospital of Philadelphia · Los Angeles, California and 6 other locations · NCT06721689

• Evaluating brain health in infants with hydrocephalus using ultrasound

  This study is testing a new ultrasound method to see if it can safely check brain health in babies with hydrocephalus.

  Recruiting Phase 2 Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT06693752

• A mobile sleep program to help teens with high blood pressure sleep longer

  This trial tries a phone/computer-based sleep extension program for 13-to-18-year-olds with recently diagnosed high blood pressure to see if they sleep more and their blood pressure goes down.

  Recruiting Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT06642246

• Increasing daily physical activity for teens with chronic kidney disease

  This 12-week program will test if an online physical-activity plan can add about 15 minutes of moderate-to-vigorous activity per day for adolescents (ages 13–18) with chronic kidney disease.

  Recruiting Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT06624358

• Collaborative care program for young Black and Latino men at risk for HIV

  This study tests a new support program to help young Black and Latino men at risk for HIV start taking prevention medication and manage their substance use better.

  Recruiting Children's Hospital of Philadelphia · Baltimore, Maryland and 1 other locations · NCT06585631

• Proactive tobacco treatment for household smokers through pediatric care

  This study is testing a new way to help household smokers quit tobacco by using support from pediatric care to see if it can improve their chances of success.

  Recruiting Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT06582693

• Natural history study of STXBP1 and SYNGAP1 related disorders

  This study is trying to learn more about STXBP1 and SYNGAP1 related disorders by collecting information from participants over five years to help improve future treatments.

  Recruiting at 5 sites Children's Hospital of Philadelphia · Palo Alto, California and 4 other locations · NCT06555965

• Transpyloric versus gastric feeding for premature infants with bronchopulmonary dysplasia

  This trial will see if feeding premature infants with bronchopulmonary dysplasia directly into the small intestine (transpyloric) versus into the stomach reduces reflux and episodes of low oxygen.

  Recruiting at 3 sites Children's Hospital of Philadelphia · Palo Alto, California and 3 other locations · NCT06534359

• Classification of severe bronchopulmonary dysplasia in infants

  This study is trying to create a new way to classify the most severe form of bronchopulmonary dysplasia in infants to see how different types of the condition affect their breathing and brain development over time.

  Recruiting Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT06475976

• Treatment for RET Fusion Thyroid Cancer in Young Patients

  This study is testing a new treatment combining selpercatinib and radioactive iodine for children and young adults with a specific type of thyroid cancer to see if it helps improve their condition after surgery.

  Recruiting at 3 sites Phase 2 Children's Hospital of Philadelphia · San Francisco, California and 4 other locations · NCT06458036

• Measuring blood flow stress in infants' pulmonary veins

  This study is testing a new way to measure blood flow in the veins of infants' hearts to see if it can help identify and treat a serious condition called pulmonary vein stenosis.

  Recruiting Phase 1 Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT06440408

• Testing driver training programs for young new drivers

  This study tests different driver training programs to see which one helps young new drivers stay safe and avoid crashes after they get their licenses.

  Recruiting Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT06413927

• Monitoring Eosinophilic Esophagitis During Oral Immunotherapy with a String Test

  This study is testing if a new string test can help find Eosinophilic Esophagitis in kids with food allergies who are getting treatment to help them tolerate those foods.

  Recruiting Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT06389994

• Using cabozantinib with ifosfamide to treat Ewing's sarcoma and osteosarcoma

  This study is testing if a new combination of cabozantinib and high-dose ifosfamide can help children and young adults with Ewing's sarcoma and osteosarcoma that hasn't responded to previous treatments.

  Recruiting at 4 sites Phase 1 Children's Hospital of Philadelphia · San Francisco, California and 3 other locations · NCT06156410

• Using a Smart Checklist to Improve Pediatric Intubation Safety in ICUs

  This study is testing a new digital checklist to see if it can make tracheal intubations safer for children in intensive care units.

  Recruiting at 6 sites Children's Hospital of Philadelphia · Little Rock, Arkansas and 5 other locations · NCT06085326

• Reducing unnecessary vancomycin use in children with suspected sepsis

  This study is testing a new approach to see if better guidelines and education can help doctors use less vancomycin in children suspected of having sepsis, which could lower the risk of kidney problems.

  Recruiting at 4 sites Children's Hospital of Philadelphia · Atlanta, Georgia and 3 other locations · NCT05975671

• Identifying biomarkers in Rett Syndrome

  This study is trying to find specific brain signals in girls with Rett Syndrome to see how they differ from girls without the condition and how these signals relate to the severity of their symptoms over time.

  Recruiting at 6 sites Children's Hospital of Philadelphia · Los Angeles, California and 5 other locations · NCT05932589

• Using lurbinectedin to treat specific tumors in children and young adults

  This study is testing if a new drug called lurbinectedin can help children and young adults with certain types of tumors, like Ewing sarcoma, by targeting the proteins that make the tumors grow.

  Recruiting at 6 sites Phase 1/2 Children's Hospital of Philadelphia · Los Angeles, California and 5 other locations · NCT05918640

• Registry and biospecimen collection for synovial sarcoma patients

  This study is collecting medical information and samples from people with synovial sarcoma to help researchers find better treatments and improve care for future patients.

  Recruiting Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT05910307

• Evaluating gastric activity in children with gastrointestinal symptoms

  This study tests how stomach activity in children with tummy problems compares to healthy kids to see if a new device can help understand their symptoms better.

  Recruiting at 5 sites Children's Hospital of Philadelphia · San Diego, California and 4 other locations · NCT05880199

• Improving safety of tracheal intubation in newborns

  This study is testing a new safety plan for intubating newborns in NICUs to see if it can lower the risk of complications during the procedure.

  Recruiting at 7 sites Children's Hospital of Philadelphia · Little Rock, Arkansas and 7 other locations · NCT05838690

• Using Larotrectinib to Improve Radioactive Iodine Treatment in Thyroid Cancer

  This study is testing if adding a drug called larotrectinib to radioactive iodine treatment can help people with a specific type of thyroid cancer that has spread to the lungs feel better.

  Recruiting at 5 sites Phase 2 Children's Hospital of Philadelphia · San Francisco, California and 5 other locations · NCT05783323

• Improving access to specialty care for concussion patients

  This study is testing a new mobile health program to help concussion patients get better care faster and improve their recovery by allowing them to share their symptoms daily with doctors.

  Recruiting Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT05741411

• Mobile health platform to improve sleep and prevent obesity in children

  This study is testing a mobile app to help kids aged 8-12 sleep longer to see if it can also help them avoid becoming overweight.

  Recruiting Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT05703347

• Combining two CAR T cell therapies for treating advanced B-ALL in children

  This study is testing if giving two types of CAR T cell therapies together can help children and young adults with advanced B-cell leukemia who haven't responded to other treatments.

  Recruiting Phase 1/2 Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT05674175

• Monitoring brain oxygen and electrical activity in newborns during major surgery

  This study looks at how brain oxygen levels and electrical activity change in newborns during major surgery to see if it affects their recovery.

  Recruiting at 3 sites Children's Hospital of Philadelphia · New York, New York and 14 other locations · NCT05673499

• Effects of passive exercise on mitochondrial diseases

  This study is testing how different types of exercise, including passive exercise, affect people with mitochondrial diseases compared to healthy individuals.

  Recruiting Phase 1 Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT05569122

• Evaluating a new imaging method for low-grade brain tumors in children

  This study is testing a new imaging method to see if it can help doctors better monitor and manage low-grade brain tumors in children.

  Recruiting Early Phase 1 Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT05555550

• Using 18F-fluciclovine PET-MRI to assess high-grade gliomas in children

  This study is testing a special imaging technique to see if it can help doctors tell the difference between real tumor growth and changes after treatment in children with high-grade brain tumors.

  Recruiting Early Phase 1 Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT05553041

• Using a new method to create CAR T cells for treating pediatric B-ALL

  This study is testing a new way to make CAR T cells faster and safer for kids with B cell Acute Lymphoblastic Leukemia (B-ALL) to see if it helps them get better treatment more quickly.

  Recruiting Phase 1/2 Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT05480449

• Exercise program for children with pulmonary hypertension

  This study is testing a 16-week exercise program to help children and teenagers with pulmonary hypertension get more active and feel better.

  Recruiting Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT05442671

• Introducing fiber foods to children with short bowel syndrome

  This study is testing how well children with short bowel syndrome can handle fiber foods, like green bean puree, to see if it helps improve their nutrition.

  Recruiting Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT05432648

• Comparing home sleep apnea testing to in-lab testing in children

  This study is testing whether home sleep apnea tests are just as good as in-lab tests for diagnosing sleep apnea in children.

  Recruiting Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT05382754

• Measuring disease progression in mitochondrial myopathy

  This study is trying to find better ways to track how primary mitochondrial myopathy changes over time in patients so that future treatments can be developed more effectively.

  Recruiting Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT05250375

• Exercise and NAD+ Supplementation for Young Cancer Survivors

  This study is testing if combining exercise with a supplement called nicotinamide riboside can help young cancer survivors improve their muscle strength and fitness.

  Recruiting at 3 sites Phase 2 Children's Hospital of Philadelphia · Duarte, California and 2 other locations · NCT05194397

• Using stem cell transplants to treat severe autoimmune diseases in young patients

  This study is testing if using stem cell transplants along with strong medications can help young people with severe autoimmune diseases like lupus and scleroderma feel better when other treatments haven't worked.

  Recruiting Phase 2 Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT05029336

• Targeted therapy to improve radioactive iodine uptake in metastatic thyroid cancer

  This study is testing if a targeted therapy can help improve how well radioactive iodine works on lung tumors in patients with advanced thyroid cancer.

  Recruiting at 9 sites Children's Hospital of Philadelphia · San Francisco, California and 8 other locations · NCT05024929

• Understanding Autosomal Dominant Polycystic Kidney Disease in Children

  This study is looking to gather medical information about how Autosomal Dominant Polycystic Kidney Disease affects children to help improve care and resources for families.

  Recruiting at 3 sites Children's Hospital of Philadelphia · Washington D.C., District of Columbia and 3 other locations · NCT04338048

• Using immune cells to treat BK virus infection in transplant patients

  This study is testing whether specially treated immune cells can help transplant patients with BK virus infections feel better and reduce the virus in their bodies.

  Recruiting Early Phase 1 Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT04293042

• Treatment for specific types of pediatric and young adult leukemia using engineered T cells

  This study is testing a special type of T cell therapy to see if it can help young patients with certain high-risk forms of leukemia feel better.

  Recruiting Phase 2 Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT04276870

• Investigating the link between sleep and blood sugar control in adolescents with Type 2 Diabetes

  This study is testing if getting more sleep can help teenagers with Type 2 Diabetes better control their blood sugar levels.

  Recruiting Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT04213547

• Matching donor red blood cells by RH genotype for sickle cell disease patients

  This study is testing if matching red blood cell transfusions to the RH genotype can help people with sickle cell disease who need regular transfusions feel better and have fewer complications.

  Recruiting Phase 1/2 Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT04156893

• Measuring oxygen levels in muscle for mitochondrial myopathy

  This study is testing a new device that measures oxygen levels in muscles during exercise to see if it can help understand how mitochondrial myopathy affects patients and improve future treatments.

  Recruiting Phase 1 Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT04086329

• Proton therapy for children with renal tumors

  This study is testing a new type of proton therapy for children with kidney tumors to see if it can reduce side effects from treatment while still being effective.

  Recruiting Early Phase 1 Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT03810651

• Using CD45RA Depleted Stem Cells to Improve Immune Recovery After Transplant

  This study is testing if using special stem cells can help patients with acute leukemia recover their immune system faster after a transplant and reduce the risk of complications.

  Recruiting Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT03810196

• Using ultrasound with contrast to assess abdominal injuries in children

  This study is testing if a special type of ultrasound can help find abdominal injuries in children with blunt trauma, instead of using a CT scan, to see if it’s a safer option.

  Recruiting at 2 sites Phase 4 Children's Hospital of Philadelphia · Rochester, Minnesota and 1 other locations · NCT03490929

• Managing seizures in critically ill children using EEG monitoring

  This study looks at how continuous EEG monitoring can help doctors manage seizures in critically ill children and improve their care in the hospital.

  Recruiting Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT03419260

• Using rifampin to treat hypercalcemia in patients with CYP24A1 mutations

  This study is testing if rifampin can help people with CYP24A1 mutations lower their high calcium levels and improve their health.

  Recruiting Phase 2 Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT03301038

• Using ultrasound to assess blood flow during hip surgery for infants with hip dysplasia

  This study is testing if using a special ultrasound during hip surgery can help doctors see blood flow in infants with hip dysplasia to prevent complications and improve surgery results.

  Recruiting Early Phase 1 Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT03107520

• Collecting data and samples from patients with leukodystrophy

  This study is collecting health information and samples from people with leukodystrophy to help find new causes and better treatments for the condition.

  Recruiting at 23 sites Children's Hospital of Philadelphia · Los Angeles, California and 22 other locations · NCT03047369

• Understanding how Alexander Disease affects patients

  This study looks at how Alexander Disease affects everyday activities like movement, speech, and swallowing in patients to help understand the condition better and guide future treatments.

  Recruiting Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT02714764

• Evaluating pediatric resuscitation quality across multiple centers

  This study is testing how different techniques of chest compressions during CPR can improve survival and brain health for children who have a cardiac arrest.

  Recruiting at 61 sites Children's Hospital of Philadelphia · Los Angeles, California and 62 other locations · NCT02708134

• Improving safety and quality of tracheal intubation in pediatric ICUs

  This study looks at how tracheal intubation is done in children's hospitals to see if there are safer and better ways to improve care for young patients.

  Recruiting at 69 sites Children's Hospital of Philadelphia · Birmingham, Alabama and 86 other locations · NCT02493478

• Access to stem cell transplant for patients without matched donors

  This study is testing a new way to help patients without a matched donor get a stem cell transplant by using a special device to reduce complications and improve their chances of recovery.

  Recruiting Early Phase 1 Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT02356653

• Examining genetics related to insulin and incretins in cystic fibrosis

  This study is trying to see how certain genes affect insulin and blood sugar levels in people with cystic fibrosis to better understand diabetes related to the condition.

  Recruiting at 2 sites Children's Hospital of Philadelphia · Philadelphia, Pennsylvania and 1 other locations · NCT01852448

• Resource for Hepato/Renal Fibrocystic Diseases

  This study is trying to collect detailed health and genetic information from people with hepato/renal fibrocystic diseases to improve understanding and treatment options for these conditions.

  Recruiting at 4 sites Children's Hospital of Philadelphia · Washington D.C., District of Columbia and 5 other locations · NCT01401998

Quick answers

How many clinical trials run by Children's Hospital of Philadelphia are recruiting right now?

85, as of November 12, 2026. 2 of them were first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 20 countries. The most sites are in United States (85 trials), Australia (4 trials), Canada (3 trials), United Kingdom (3 trials), India (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 10, Phase 1: 8, Phase 1/2: 8, Early Phase 1: 6. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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