Implementing SMART asthma care in pediatric primary clinics

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The trial compares usual care to an electronic health record clinical decision support intervention combined with clinician education (CDS+) to increase adoption of SMART for Step 3–4 pediatric asthma. Randomization is at the clinic level among Children's Hospital of Philadelphia (CHOP) primary care practices, and outcomes will be reported at visit-, patient-, and clinic-levels. Eligible patients are children aged 5–18 with evidence of uncontrolled asthma and recent prescriptions for inhaled corticosteroid–containing maintenance therapy. This is the first of two linked implementation-effectiveness records, with a later phase adding population health management strategies.

Why it matters

Who can join: the full rules

Clinic Inclusion Criteria:

* The clinic is a pediatric primary care clinic that is part of the Children's Hospital of Philadelphia (CHOP) Pediatric Research Consortium (PeRC).
* The clinic agrees to participate in SMART \& SIMPLE study.

Patient Inclusion Criteria:

* Ages 5-18 years;
* Has clinic visit at participating practice during study interval (sick, well, or follow-up)
* Prescribed at least one prescription for an inhaled corticosteroid (ICS) or ICS-long-acting beta agonist (ICS-LABA) for maintenance asthma therapy in the past year;
* Evidence of uncontrolled asthma as determined by: (1) uncontrolled Asthma Control Tool score in the past 6 months OR (2) two or more systemic corticosteroids prescribed for an asthma exacerbation in the past 12 months (one occurring in the past 6 months)

Clinic Exclusion Criteria:

\- The clinic is not willing to participate in SMART \& SIMPLE study interventions.

Patient Exclusion Criteria:

\- Transferred clinics or left the CHOP Pediatric Care Network.

Where it's running

• Children's Hospital of Philadelphia
  Philadelphia, Pennsylvania, United States Recruiting

Study contacts

• Study coordinator: Chén Kenyon, MD, MSHP
• Email: kenyonc@chop.edu
• Phone: 267-426-6339

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• N-WATCH: Can a simple breath device help monitor asthma in kids

  This study tests the N-Tidal C device to see if it helps monitor asthma in children aged 5 to under 16 who have wheeze or asthma and are not critically ill.

  Recruiting at 2 sites University of Nottingham · Nottingham, Nottinghamshire and 1 other locations · NCT07833826

• Smart Inhaler Use at Home for Adolescents with IDD and Asthma

  This study tests whether daily use of active smart inhalers at home helps adolescents with intellectual disabilities manage asthma better.

  Recruiting Children's Hospital Los Angeles · Los Angeles, California · NCT07746921

• ASMact: Managing bronchial asthma attacks in children

  This study tries a GINA 2025-based staff education and care-standardization approach to see if emergency treatment for children aged 6–17 with acute asthma attacks improves outcomes.

  Recruiting at 2 sites Meyer Children's Hospital IRCCS · Ferrara, FE and 1 other locations · NCT07412769

• Biomarkers and Respiratory Omics in Children: Predicting Disease Course

  This study tests whether biomarkers from the lungs and blood can predict how asthma and protracted bacterial bronchitis in children will progress and respond to current therapies.

  Recruiting Medical University of Warsaw · Warsaw · NCT07232550

• Using technology and school–clinic coordination to improve asthma care for children.

  This project will try a tech-enabled program plus school care coordination to help children ages 4–12 with persistent or uncontrolled asthma follow guideline-based treatment and have fewer symptoms and school problems.

  Recruiting Montefiore Medical Center · The Bronx, New York · NCT07224061

• Boosting use of SMART inhaler therapy for children with moderate-to-severe asthma

  This project will test whether adding community health workers and nurse care managers to electronic health record decision support and education helps children ages 5–18 with uncontrolled asthma use single maintenance and reliever therapy (SMART).

  Recruiting Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT07138027

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.