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Evaluating pediatric resuscitation quality across multiple centers

Quality of Pediatric Resuscitation in a Multicenter Collaborative: An Observational Study

Observational Children's Hospital of Philadelphia · NCT02708134

This study is testing how different techniques of chest compressions during CPR can improve survival and brain health for children who have a cardiac arrest.

Quick facts

Study typeObservational
Enrollment7000 (estimated)
Ages0 Years to 18 Years
SexAll
SponsorChildren's Hospital of Philadelphia Academic / other
Locations61 sites (Los Angeles, California and 60 other locations)
Trial IDNCT02708134 on ClinicalTrials.gov

What this trial studies

This observational study focuses on pediatric cardiac arrests to assess how different aspects of chest compression mechanics, such as rate and depth, affect patient outcomes. It aims to gather data on the quality of cardiopulmonary resuscitation (CPR) and the subsequent care provided after cardiac arrest. By analyzing these factors, the study seeks to improve neurological outcomes for children who experience cardiac arrest. The research involves multiple centers and utilizes specialized devices to measure CPR quality.

Who should consider this trial

Good fit: Ideal candidates for this study are children aged between 37 weeks gestational age and 17 years who have received chest compressions for at least one minute.

Not a fit: Patients who are on extracorporeal membrane oxygenation (ECMO) therapy at the beginning of the CPR event may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved survival rates and neurological outcomes for children experiencing cardiac arrest.

How similar studies have performed: Other studies have shown success in improving CPR techniques and outcomes, making this approach both relevant and potentially impactful.

Eligibility criteria

Show full inclusion / exclusion criteria 
Inclusion Criteria:

* Patient received chest compressions for at least 1 minute
* Patient between gestational age ≥37 weeks and 18 years of age

Exclusion Criteria:

* Patient on veno-arterial extracorporeal membrane oxygenation (ECMO) therapy at beginning of CPR event

Where this trial is running

Los Angeles, California and 60 other locations

+11 more sites — see ClinicalTrials.gov for the full list.

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
View on ClinicalTrials.gov → Find more trials like this →
Conditions Cardiac ArrestCardiopulmonary ArrestChest compressionsCardiopulmonary ResuscitationPediatric
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.