Proactive tobacco treatment for household smokers through pediatric care
Official title: Refer2Quit: Evaluating a Proactive, Tailored, Population Health Approach for Tobacco Treatment for Household Smokers Through a Pediatric Care Network
Run by Children's Hospital of Philadelphia · NCT06582693 · Data updated 2026-11-12
This study is testing a new way to help household smokers quit tobacco by using support from pediatric care to see if it can improve their chances of success.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 3200 (estimated) |
| Sponsor | Children's Hospital of Philadelphia Academic / other |
| Locations | 1 site (Philadelphia, Pennsylvania) |
| Status | Recruiting |
| Started | September 6, 2024 |
| Main results expected | March 1, 2027 |
| Study ends | March 1, 2027 |
| Registry record updated | August 6, 2026 |
| Trial ID | NCT06582693 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults aged 18 and older who are current combustible tobacco users and have a valid cell phone number.
✕Probably not a fit
Patients who are under 18 years of age or do not identify as current combustible tobacco users will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial evaluates the effectiveness of the Refer2Quit intervention, which aims to increase tobacco treatment and quit rates among household smokers by leveraging a clinical decision support system within electronic health records. Participants will be recruited from outpatient primary care practices associated with the Children's Hospital of Philadelphia, and will be randomly assigned to either an intervention group receiving tailored tobacco treatment options or a control group. The study also seeks to understand the characteristics of household members and pediatric patients that influence the success of the intervention.
Why it matters
Potential benefit: If successful, this approach could significantly improve smoking cessation rates among household smokers, benefiting both the smokers and their families.
How similar studies have gone: Other studies have shown success with similar population health approaches for tobacco cessation, indicating potential for effectiveness in this intervention.
Who can join: the full rules
Show full inclusion / exclusion criteria
Adult Intervention Subject Inclusion Criteria * Males or females ages ≥18 years in age * Self-identify as a current combustible tobacco user * Have a valid cell phone number Child Intervention Subject Inclusion Criteria * Must be a CHOP patient Adult Intervention Subject Exclusion Criteria * \<18 years in age. * Indicates no combustible tobacco smoking Child Intervention Subject Exclusion Criteria * Not a CHOP patient Adult Control Subject Inclusion Criteria * Males or females ages ≥18 years in age * Self-identify as a current combustible tobacco user * Have a valid cell phone number Child Control Subject Inclusion Criteria * Must be a CHOP patient Adult Control Subject Exclusion Criteria * \<18 years in age. * Indicates no combustible tobacco smoking Child Control Subject Exclusion Criteria * Not a CHOP patient
Where it's running
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Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, United States Recruiting
Study contacts
- Principal investigator: Brian P Jenssen, MD, MSHP — Children's Hospital of Philadelphia
- Study coordinator: Brian P Jenssen, MD, MSHP
- Email: jenssenb@chop.edu
- Phone: 267-559-1566
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.