Managing seizures in critically ill children using EEG monitoring
Electrographic Seizure Management and Neurobehavioral Outcomes in Critically Ill Children
Children's Hospital of Philadelphia · NCT03419260
This study looks at how continuous EEG monitoring can help doctors manage seizures in critically ill children and improve their care in the hospital.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 2500 (estimated) |
| Ages | 1 Month to 18 Years |
| Sex | All |
| Sponsor | Children's Hospital of Philadelphia (other) |
| Locations | 1 site (Philadelphia, Pennsylvania) |
| Trial ID | NCT03419260 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on critically ill children who require continuous EEG monitoring to identify and manage electrographic seizures. The study aims to track these patients to identify risk factors for seizures and develop prediction models to optimize EEG resource allocation. Additionally, it evaluates the safety of current seizure management strategies guided by a standardized EEG monitoring pathway at the Children's Hospital of Philadelphia. By analyzing data from these patients, the study seeks to improve seizure management in pediatric intensive care settings.
Who should consider this trial
Good fit: Ideal candidates are critically ill children aged 1 month to 18 years who require clinically indicated continuous EEG monitoring.
Not a fit: Patients who are expected to have their technological support discontinued within two days or those admitted for intracranial EEG monitoring may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the identification and management of seizures in critically ill children, leading to better patient outcomes.
How similar studies have performed: While there is limited data on optimal seizure management strategies, similar studies have shown promise in using EEG monitoring for seizure identification in critically ill patients.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Care in the Children's Hospital of Philadelphia Pediatric ICU. 2. Clinically indicated continuous EEG monitoring. 3. Age \> 1 month to 18 years. Exclusion Criteria: 1. Admitted for Phase 2 (intracranial) EEG monitoring. 2. Intensivist expects to discontinue technological support in the next two days given underlying medical or neurological problems.
Where this trial is running
Philadelphia, Pennsylvania
- Children's Hospital of Philadelphia — Philadelphia, Pennsylvania, United States (RECRUITING)
Study contacts
- Principal investigator: Nicholas S Abend, MD — Children's Hospital of Philadelphia
- Study coordinator: Nicholas S Abend, MD
- Email: abend@chop.edu
- Phone: 215-590-1719
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Seizures, seizures, status epilepticus, EEG monitoring