Condition

Uterine Cancer clinical trials and research

• 22Clinical trials
• 12NIH research projects
• 1New in 30 days
• 10Countries

Newest Uterine Cancer clinical trials

All recruiting trials (22)

• Radiotherapy for gynecologic cancer with up to 10 metastatic sites

  This registry follows adults with gynecologic cancer who have 1 to 10 active metastatic lesions and are treated with radiotherapy as part of routine care to see how such treatments work in real-world settings.

  Recruiting Affidea Nu-med Center of Oncological DIagnostics and Therapy · Zamość · NCT07883798

• KQB368 as a single-drug treatment for adults with advanced solid tumors

  This study tests whether taking KQB368 by mouth every day can help shrink tumors and is safe for adults with advanced solid cancers.

  Recruiting at 14 sites Phase 1 Kumquat Biosciences Inc. · Los Angeles, California and 13 other locations · NCT07542704

• Collecting blood and leftover tumor tissue to test molecular residual disease (MRD) detection

  This project will test whether blood and leftover tumor tissue from adults with certain solid tumors can be used with Natera's MRD blood tests to find tiny amounts of cancer (ctDNA) after treatment.

  Recruiting Natera, Inc. · Austin, Texas · NCT07318051

• Initial testing of an educational approach to genetic services for families at risk of Lynch syndrome

  This pilot study tests whether an information letter alone or with a booklet helps at-risk relatives decide about pursuing genetic services for Lynch syndrome.

  Recruiting University of Alabama at Birmingham · Birmingham, Alabama · NCT07106359

• Molecular and cellular analysis of uterine lavage from gynecologic surgery

  This will try a new uterine lavage catheter to collect samples from up to 50 adults having gynecologic surgery to see what cells are present.

  Recruiting Stanford University · Palo Alto, California · NCT07044505

• Zanzalintinib with paclitaxel for recurrent high-grade uterine cancer

  This trial tests whether adding zanzalintinib to paclitaxel is safe and helps people with recurrent high-grade uterine (endometrial) cancer respond to treatment.

  Recruiting at 2 sites Phase 1 Washington University School of Medicine · San Francisco, California and 3 other locations · NCT06795009

• Using Belzutifan to treat recurrent clear cell ovarian carcinoma

  This study is testing if a new targeted therapy called Belzutifan can help people with recurrent clear cell ovarian cancer feel better and manage their disease.

  Recruiting at 2 sites Phase 2 Dana-Farber Cancer Institute · Boston, Massachusetts and 1 other locations · NCT06677190

• Creating a non-invasive test for ruling out gynecological cancer in women over 45

  This study is testing a new non-invasive test to see if it can help women over 45 with abnormal bleeding find out if they have gynecological cancer.

  Recruiting at 13 sites PinkDx, Inc. · Birmingham, Alabama and 15 other locations · NCT06527157

• Analyzing shopping habits to improve early cancer diagnosis

  This study is trying to see if changes in shopping habits can help spot cancer earlier by looking at purchase data from loyalty cards of people recently diagnosed with cancer and those without it.

  Recruiting Imperial College London · London · NCT06447064

• Analyzing saliva for diagnosing gynecological conditions

  This study is testing if analyzing saliva can help doctors diagnose gynecological conditions like endometriosis and ovarian cancer in both patients with symptoms and those without.

  Recruiting at 5 sites Ziwig · Angers and 12 other locations · NCT06392997

• Investigating Azenosertib for Uterine Serous Carcinoma

  This study is testing a new drug called Azenosertib to see if it can help people with persistent or recurring uterine serous carcinoma.

  Recruiting at 2 sites Phase 2 Dana-Farber Cancer Institute · Boston, Massachusetts and 1 other locations · NCT06369155

• Biobank for studying ALS and Alzheimer's diseases

  This study is collecting blood, skin samples, and health information from people to see how genetics might help us understand and find treatments for ALS and Alzheimer's disease.

  Recruiting New York Stem Cell Foundation Research Institute · New York, New York · NCT06203106

• Comparing two types of sutures for vaginal cuff closure in laparoscopic hysterectomy

  This study is testing whether a new type of suture can close the vaginal cuff faster than a standard suture for women having laparoscopic hysterectomy, without causing more complications.

  Recruiting at 2 sites Aesculap AG · Frankfurt am Main, Hesse and 1 other locations · NCT06024109

• Fasting regimen for women undergoing chemotherapy after surgery for gynecologic cancers

  This study is testing if an alternate day fasting diet can help women with ovarian and endometrial cancers feel better during chemotherapy and improve their quality of life.

  Recruiting Northwestern University · Chicago, Illinois · NCT05990426

• Using ultrasound for real-time imaging in uterine cancer treatment

  This study is testing if combining ultrasound with MRI can help doctors place treatment needles more accurately for women with uterine cancer.

  Recruiting Duke University · Durham, North Carolina · NCT05977621

• Using PET imaging to evaluate estrogen receptor activity in uterine cancer

  This study is testing a special type of imaging to see how well estrogen receptors are working in women with recurrent or advanced uterine cancer to help guide their treatment.

  Recruiting Phase 2 Abramson Cancer Center at Penn Medicine · Philadelphia, Pennsylvania · NCT05916196

• Proton therapy for treating gynecologic cancer after surgery

  This study is testing a new type of radiation therapy after surgery to see if it helps women with cervical and endometrial cancer while causing fewer side effects.

  Recruiting at 3 sites Phase 2 Abramson Cancer Center at Penn Medicine · Voorhees Township, New Jersey and 2 other locations · NCT05758688

• Testing Rinatabart Sesutecan for advanced solid tumors

  This study is testing a new drug called Rinatabart Sesutecan to see if it can safely help people with advanced solid tumors, like certain types of ovarian and endometrial cancers.

  Recruiting at 67 sites Phase 1/2 Genmab · Phoenix, Arizona and 66 other locations · NCT05579366

• Combining Cabozantinib and Dostarlimab for Recurrent Gynecologic Carcinosarcoma

  This study is testing if combining two drugs, Cabozantinib and Dostarlimab, can help people with recurrent gynecologic carcinosarcoma who have already had chemotherapy.

  Recruiting Phase 1/2 University of Alabama at Birmingham · Birmingham, Alabama · NCT05559879

• Using fecal microbiota transplantation to treat diarrhea or colitis in cancer patients

  This study is testing whether a treatment using healthy gut bacteria can help cancer patients with diarrhea or colitis caused by their cancer treatment feel better.

  Recruiting Phase 1 M.D. Anderson Cancer Center · Houston, Texas · NCT04038619

• Developing a liquid biopsy protocol for cancer research at Princess Margaret

  This study is trying to create a simple way to collect blood samples from cancer patients to see if analyzing certain molecules in their blood can help doctors understand their cancer better and track how it changes over time.

  Recruiting University Health Network, Toronto · Toronto, Ontario · NCT03702309

• Using MRI to improve gynecologic cancer treatment with brachytherapy

  This study is testing if using MRI instead of traditional CT scans can help improve brachytherapy treatment for women with gynecologic cancers by better targeting tumors and reducing radiation exposure to healthy tissues.

  Recruiting Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · Baltimore, Maryland · NCT02993900

NIH-funded research (12)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Modeling to Prevent and Control Uterine Cancer

  A national modeling effort uses computer simulations to inform better prevention, screening, and treatment of uterine cancer for women.

  NIH research Tufts Medical Center · Boston, United States · NIH-11522504

• Comparative modeling to guide uterine cancer care

  This grant uses computer models to help doctors and patients understand how to make better decisions about uterine cancer care.

  NIH research Tufts Medical Center · Boston, United States · NIH-11495550

• Using DNA damage drugs to help the immune system fight uterine cancer

  This project combines drugs that increase tumor DNA damage with immunotherapy to help people with recurrent microsatellite-stable uterine cancer who haven't responded to current treatments.

  NIH research Dana-Farber Cancer Inst · Boston, United States · NIH-11323901

• Dual ATR and PI3K-targeted therapy for uterine cancer

  This project will try combining two drugs that block ATR and PI3K to better stop uterine cancers, especially tumors with ARID1A changes or other DNA replication stress.

  NIH research Dana-Farber Cancer Inst · Boston, United States · NIH-11323897

• WEE1-targeted treatment for uterine serous and p53-mutant uterine cancer

  Testing a drug that blocks the WEE1 protein to try to shrink uterine serous cancers and other uterine cancers with p53 mutations.

  NIH research Dana-Farber Cancer Inst · Boston, United States · NIH-11323894

• Treating uterine (endometrial) cancer by targeting DNA damage and replication stress

  This project develops new treatment approaches that exploit DNA repair weaknesses to help women with advanced or recurrent uterine (endometrial) cancer who need additional options.

  NIH research Dana-Farber Cancer Inst · Boston, United States · NIH-11323893

• Computer models to improve prevention and care for uterine (endometrial) cancer

  Researchers are using computer models to compare prevention, screening, and treatment options for women at risk of or living with uterine cancer.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11187143

• Improving immune response in uterine cancer by targeting DNA damage

  This study is looking at a new way to help people with recurring uterine cancers by using special treatments that could make their tumors more responsive to the immune system, potentially leading to better results and fewer side effects.

  NIH research Dana-Farber Cancer Inst · Boston, United States · NIH-11070315

• Combining two treatments to target uterine cancer

  This study is looking at how two types of cancer treatments, ATR and PI3K inhibitors, can work together to help improve outcomes for people with uterine cancer, especially those with tumors that are under a lot of stress from cell replication.

  NIH research Dana-Farber Cancer Inst · Boston, United States · NIH-11070306

• Targeting a specific protein in certain types of uterine cancer

  This study is looking at a type of uterine cancer that can be hard to treat, and it’s testing a new approach that targets a specific protein to see if it can help improve treatment options for patients like you.

  NIH research Dana-Farber Cancer Inst · Boston, United States · NIH-11070304

• Improving treatment for uterine cancer by targeting DNA damage responses

  This study is looking for better ways to treat women with advanced or returning uterine cancer by focusing on a problem that makes cancer cells unstable, and it aims to create new therapies using cutting-edge techniques.

  NIH research Dana-Farber Cancer Inst · Boston, United States · NIH-11070302

• Modeling strategies to prevent and control uterine cancer

  This study is looking at ways to better prevent, screen for, and treat uterine cancer, especially for women from different racial backgrounds, so that doctors and health leaders can make smarter choices about care.

  NIH research Columbia University Health Sciences · New York, United States · NIH-10926837

Related topics

Quick answers

How many Uterine Cancer clinical trials are recruiting right now?

22, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 10 countries. The most sites are in United States (17 trials), China (1 trial), Japan (1 trial), South Korea (1 trial), Germany (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 4, Phase 1: 3, Phase 1/2: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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