Comparing two types of sutures for vaginal cuff closure in laparoscopic hysterectomy
Official title: Prospective, International, Randomized, Multicentric, Controlled Study on the Performance of SYMMCORA® Mid-term Unidirectional Barbed Suture Versus V-loc® Suture Material in Patients Undergoing Laparoscopic Total Hysterectomy
Run by Aesculap AG · NCT06024109 · Data updated 2026-11-12
This study is testing whether a new type of suture can close the vaginal cuff faster than a standard suture for women having laparoscopic hysterectomy, without causing more complications.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | Women only |
| Enrollment | 132 (estimated) |
| Sponsor | Aesculap AG Industry-sponsored |
| Locations | 2 sites (Frankfurt am Main, Hesse and 1 other locations) |
| Status | Recruiting |
| Started | March 19, 2024 |
| Main results expected | January 2027 |
| Study ends | August 2027 |
| Registry record updated | June 2, 2026 |
| Trial ID | NCT06024109 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are females aged 18 and older who are scheduled for an elective laparoscopic total hysterectomy.
✕Probably not a fit
Patients undergoing emergency or open surgeries, or those with allergies to the suture materials, will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to compare the performance of SYMMCORA®, a new unidirectional barbed suture, against the conventional V-Loc® suture material in patients undergoing laparoscopic total hysterectomy. The primary focus is to evaluate which suture allows for a quicker closure of the vaginal cuff without increasing complication rates. The study will be conducted in a routine clinical setting, with participants randomly assigned to one of the two suture groups. Both sutures are CE-marked and will be used as intended, ensuring no additional invasive measures or burdens on the patients.
Why it matters
Potential benefit: If successful, this study could lead to faster surgical procedures and improved recovery times for patients undergoing laparoscopic hysterectomy.
How similar studies have gone: Previous studies have shown promising results with similar suture materials, indicating potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Females undergoing an elective, laparoscopic total hysterectomy * Age ≥ 18 years * Written informed consent Exclusion Criteria: * Emergency surgery * Open surgery * Patients undergone immunosuppressive drug treatment within the prior 6 months * Patients with hypersensitivity or allergy to the suture material. * Participation in another clinical study * Non-compliance of patient
Where it's running
-
Klinikum Sachsenhausen der DGD
Frankfurt am Main, Hesse, Germany Recruiting -
Hospital Sant Joan de Déu de Manresa
Manresa, Barcelona, Spain Recruiting
Study contacts
- Principal investigator: Amadeus Hornemann, Prof. Dr. — Klinikum Sachsenhausen der DGD
- Study coordinator: Petra Baumann
- Email: petra.baumann@aesculap.de
- Phone: +49746195
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.