Molecular and cellular analysis of uterine lavage from gynecologic surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective, consecutively-enrolled cohort of up to 50 adults undergoing gynecologic surgery at Stanford who will each have a uterine lavage sample collected with a novel catheter. The primary aim is to test the clinical and technical feasibility of collecting uterine lavage and to describe the molecular and cellular composition of the samples. Collected samples will undergo molecular and cellular profiling to characterize cell types and any disease-related signals. The procedure is performed intraoperatively and does not change the participant's planned surgical care.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Undergoing gynecologic surgery with Stanford Healthcare
* Intact uterus and cervix
* At least one intact fallopian tube and ovary (on the same side)
* Aged 18 years or older
* Ability to understand and the willingness to provide written informed consent.

Exclusion Criteria:

* Known endometrial or cervical cancer or endometrial or cervical intraepithelial neoplasia
* Status post bilateral salpingectomy or tubal ligation
* Lack of consenting capacity
* Positive preoperative pregnancy test
* Active uterine bleeding (i.e. menses, etc.)
* Intrauterine device in place
* Non-English speaking (requires interpretor)

Where it's running

• Stanford University
  Palo Alto, California, United States Recruiting

Study contacts

• Principal investigator: James Ford, MD — Stanford University
• Study coordinator: Rozelle Laquindanum
• Email: rlaquind@stanford.edu
• Phone: (650) 724-9948

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.