Computer models to improve prevention and care for uterine (endometrial) cancer
Comparative Modeling for the Prevention and Control of Uterine Cancer
['FUNDING_U01'] · COLUMBIA UNIVERSITY HEALTH SCIENCES · NIH-11187143
Researchers are using computer models to compare prevention, screening, and treatment options for women at risk of or living with uterine cancer.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | COLUMBIA UNIVERSITY HEALTH SCIENCES (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-11187143 on ClinicalTrials.gov |
What this research studies
As someone affected by uterine cancer, you would hear that multiple research teams are building computer models that simulate how the disease starts and progresses. The models include known risk factors such as age and rising obesity rates and represent both less aggressive (type I) and more aggressive (type II) tumors. Teams will use these models to compare prevention strategies, screening approaches, and treatment plans (including adjuvant therapy and immunotherapy), and to estimate benefits, harms, and costs. The goal is to show which choices could lower future cases and deaths and how changing population trends influence outcomes.
Who could benefit from this research
Good fit: Women at risk for or diagnosed with uterine (endometrial) cancer—including those with obesity or other known risk factors—are the population this work focuses on.
Not a fit: People without uterine/endometrial cancer or with unrelated rare cancer types are unlikely to see direct benefit from this modeling project.
Why it matters
Potential benefit: Could guide better prevention, screening, and treatment choices that reduce uterine cancer cases and deaths and inform public-health decisions.
How similar studies have performed: Similar comparative modeling efforts (for example CISNET models for breast and colorectal cancer) have successfully informed screening and prevention policies, and this applies that approach to uterine cancer.
Where this research is happening
NEW YORK, UNITED STATES
- COLUMBIA UNIVERSITY HEALTH SCIENCES — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WRIGHT, JASON — COLUMBIA UNIVERSITY HEALTH SCIENCES
- Study coordinator: WRIGHT, JASON
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancer Cause, Cancer Control, Cancer Control Science, Cancer Etiology, Cancer Intervention and Surveillance Modeling Network