Condition

Vulvar Cancer clinical trials and research

• 22Clinical trials
• 2New in 30 days
• 10Countries

Newest Vulvar Cancer clinical trials

All recruiting trials (22)

• Methylation markers in self-samples to help detect gynecological cancers

  This study tests whether self-collected urine and vaginal samples can reveal DNA methylation or other genetic markers that indicate endometrial, ovarian, vulvar, or vaginal cancers in women who are at risk or have postmenopausal bleeding.

  Recruiting Universiteit Antwerpen · Edegem, Antwerp · NCT07902375

• Radiotherapy for gynecologic cancer with up to 10 metastatic sites

  This registry follows adults with gynecologic cancer who have 1 to 10 active metastatic lesions and are treated with radiotherapy as part of routine care to see how such treatments work in real-world settings.

  Recruiting Affidea Nu-med Center of Oncological DIagnostics and Therapy · Zamość · NCT07883798

• Testing trastuzumab deruxtecan (T‑DxD) for HER2‑positive advanced solid tumors

  This will test whether trastuzumab deruxtecan (T‑DxD) helps adults in the US with HER2‑positive (IHC 3+) locally advanced, unresectable, or metastatic solid tumors who have had prior systemic treatment and have no satisfactory alternative options.

  Recruiting at 18 sites AstraZeneca · Birmingham, Alabama and 17 other locations · NCT07124000

• Using Belzutifan to treat recurrent clear cell ovarian carcinoma

  This study is testing if a new targeted therapy called Belzutifan can help people with recurrent clear cell ovarian cancer feel better and manage their disease.

  Recruiting at 2 sites Phase 2 Dana-Farber Cancer Institute · Boston, Massachusetts and 1 other locations · NCT06677190

• Investigation of recurrence detection in vulva cancer patients

  This study is testing how well doctors can detect if vulva cancer comes back in women by looking at their symptoms and checking for cancer DNA in their blood over two years.

  Recruiting at 2 sites University of Aarhus · Aarhus N and 1 other locations · NCT06495554

• Analyzing shopping habits to improve early cancer diagnosis

  This study is trying to see if changes in shopping habits can help spot cancer earlier by looking at purchase data from loyalty cards of people recently diagnosed with cancer and those without it.

  Recruiting Imperial College London · London · NCT06447064

• Biobank for studying ALS and Alzheimer's diseases

  This study is collecting blood, skin samples, and health information from people to see how genetics might help us understand and find treatments for ALS and Alzheimer's disease.

  Recruiting New York Stem Cell Foundation Research Institute · New York, New York · NCT06203106

• Using indocyanine green (ICG) dye alone to find sentinel lymph nodes in early vulvar cancer

  This will test whether near-infrared indocyanine green (ICG) alone can find sentinel lymph nodes as well as ICG plus technetium in adults with early-stage vulvar cancer.

  Recruiting Hamilton Health Sciences Corporation · Hamilton, Ontario · NCT06039111

• Using optical guidance for sentinel node biopsy in vulvar cancer

  This study is testing if using a special dye can help doctors find lymph nodes in women with early-stage vulvar cancer, to see if it makes the procedure easier and more accurate.

  Recruiting Copenhagen University Hospital, Rigshospitalet · Copenhagen · NCT06029504

• Reiki therapy to help patients with gynecological cancers undergoing brachytherapy

  This study tests if Reiki therapy can help reduce anxiety, pain, and depression in women with gynecological cancers who are about to start brachytherapy.

  Recruiting Phase 2 University of Utah · Salt Lake City, Utah · NCT05979610

• Investigating CRP Levels in Women with Advanced Gynecological Cancers Under Immunotherapy

  This study is trying to see if changes in a blood marker called CRP can help predict how well women with advanced gynecological cancers respond to immunotherapy.

  Recruiting University Hospital Tuebingen · Tübingen · NCT05914974

• E7 T-cell therapy for advanced HPV-related cancers

  This study is testing a new treatment using specially modified immune cells to see if it can help people with advanced cancers linked to HPV feel better and live longer.

  Recruiting at 2 sites Phase 1/2 Rutgers, The State University of New Jersey · New Brunswick, New Jersey and 1 other locations · NCT05639972

• Stratifying vulvar squamous cell carcinoma by HPV and p53 to guide surgical excision

  See if using HPV (p16) and p53 test results to guide how much tissue is removed during surgery helps women with early-stage vulvar squamous cell carcinoma.

  Recruiting British Columbia Cancer Agency · Vancouver, British Columbia · NCT05576831

• Electrochemotherapy for vulvar cancer treatment

  This study is testing if a new treatment called electrochemotherapy, which combines two drugs, can help women with relapsed vulvar cancer feel better and live longer compared to using just one of the drugs.

  Recruiting Phase 2 IRCCS Azienda Ospedaliero-Universitaria di Bologna · Bologna, Bo · NCT05395962

• Examining the effects of brachytherapy on gynecological cancers

  This study looks at how well brachytherapy works for women aged 18 to 80 with different types of gynecological cancers.

  Recruiting Zhejiang Cancer Hospital · Hangzhou, Zhejiang · NCT05242861

• Chemoradiation for vulvar cancer patients with large sentinel node metastasis

  This study is testing if combining chemotherapy and radiation can be a safer and more effective treatment for women with early-stage vulvar cancer who have larger cancer spread in their lymph nodes, instead of having surgery.

  Recruiting at 27 sites Phase 2 University Medical Center Groningen · Orange, California and 26 other locations · NCT05076942

• Combining Atezolizumab and Tivozanib for Treating Certain Cancer Types

  This study is testing a new combination of two cancer drugs, Atezolizumab and Tivozanib, to see if they can help people with tough-to-treat cancers like bile duct, gallbladder, breast, and neuroendocrine tumors.

  Recruiting Phase 1/2 University of Florida · Gainesville, Florida · NCT05000294

• Evaluating a 9-valent HPV vaccine in healthy Chinese women

  This study is testing a new 9-valent HPV vaccine in healthy Chinese women aged 20-45 to see how well it works and if it's safe for preventing HPV-related cancers.

  Recruiting Phase 3 Shanghai Bovax Biotechnology Co., Ltd. · Liuzhou, Guangxi · NCT04422366

• Using MRI scans to monitor cancer treatment response during radiation therapy

  This study is testing if regular MRI scans can help doctors see how well radiation therapy is working for patients with advanced cancers like glioblastoma and esophageal cancer.

  Recruiting at 2 sites Dana-Farber Cancer Institute · Boston, Massachusetts and 1 other locations · NCT04188535

• Screening for anal cancer in women with vulvar lesions

  This study is testing if screening for anal cancer with Pap smears can help women over 40 who have vulvar lesions catch any problems early and improve their health.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT03061435

• Using MRI to improve gynecologic cancer treatment with brachytherapy

  This study is testing if using MRI instead of traditional CT scans can help improve brachytherapy treatment for women with gynecologic cancers by better targeting tumors and reducing radiation exposure to healthy tissues.

  Recruiting Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · Baltimore, Maryland · NCT02993900

• Collecting specimens and data for early detection and prevention of ovarian cancer

  This study is trying to find better ways to detect and prevent ovarian cancer early by collecting blood and tissue samples from people at high risk.

  Recruiting Northwestern University · Chicago, Illinois · NCT00005095

Related topics

Quick answers

How many Vulvar Cancer clinical trials are recruiting right now?

22, as of November 12, 2026. 2 of them were first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 10 countries. The most sites are in United States (10 trials), Canada (3 trials), Denmark (2 trials), China (2 trials), Italy (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 4, Phase 1/2: 2, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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