Home › Trials › NCT07034300
Clinical trial Recruiting at 1 site Phase 4 Interventional Ages 18 to 60

Lidocaine versus lidocaine plus dexmedetomidine for IV regional anesthesia in upper limb surgery

Official title: Comparison of Lidocaine Alone Versus Lidocaine With Dexmedetomidine for Intravenous Regional Anesthesia (IVRA)

Run by Fatima Memorial Hospital · NCT07034300 · Data updated 2026-11-12

This trial will test whether adding dexmedetomidine to lidocaine for intravenous regional anesthesia gives better pain relief and longer-lasting analgesia for adults having elective upper limb surgery under 45 minutes.

More Post Operative Pain trials

Quick facts

PhasePhase 4
Study typeInterventional
Ages18 Years to 60 Years
SexAll
Enrollment90 (estimated)
SponsorFatima Memorial Hospital
Academic / other
Locations1 site (Lahore, Punjab Province)
StatusRecruiting
StartedMay 21, 2025
Main results expectedAugust 21, 2025
Study endsAugust 31, 2025
Registry record updatedJune 24, 2025
Trial IDNCT07034300 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults scheduled for elective upper limb surgery under 45 minutes who are ASA physical status I–II and do not have sleep apnea, BMI >30, heart block, or uncontrolled hypertension.

Probably not a fit

Patients with sleep apnea, BMI over 30, heart block, uncontrolled hypertension, or those needing longer or different types of surgery are unlikely to benefit from participation.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Participants undergoing elective upper limb surgery under 45 minutes receive intravenous regional anesthesia with a pneumatic tourniquet and injection of local anesthetic into the isolated limb. One group will receive lidocaine alone and the other will receive lidocaine combined with dexmedetomidine. Pain scores, duration of analgesia, and tourniquet-related discomfort will be recorded to compare the two approaches. Patients must be ASA I–II and meet exclusion criteria such as sleep apnea, BMI over 30, heart block, or uncontrolled hypertension.

Why it matters

Potential benefit: If successful, adding dexmedetomidine could provide longer postoperative pain relief and reduce intraoperative tourniquet discomfort.

How similar studies have gone: Previous trials of adding dexmedetomidine or other alpha-2 agonists to regional anesthetics have often shown prolonged analgesia and reduced opioid needs, though results and side-effect profiles have varied.

Who can join: the full rules

Show full inclusion / exclusion criteria 
Inclusion Criteria:

* American Society of Anesthesiology Status I
* American Society of Anesthesiology Status II
* Elective surgery
* Surgery duration \<45 minutes

Exclusion Criteria:

* Sleep apnea
* BMI \>30
* Heart block
* uncontrolled hypertension

Where it's running

  • Department of Anesthesiology, Fatima Memorial Hospital
    Lahore, Punjab Province, Pakistan     Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
View on ClinicalTrials.gov ↗ Find more trials like this →
Browse more
Post Operative Pain 71Regional Anesthesia 22Fatima Memorial Hospital 3
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.