parkinson's disease Clinical Trials and Research
Also known as: parkinson's, pd, shaking palsy, idiopathic parkinsonism, paralysis agitans, primary parkinsonism · ICD-10: G20
Parkinson's disease is a progressive neurological disorder that primarily affects movement. Clinical trial research is actively exploring new ways to manage symptoms, slow disease progression, and ultimately find a cure. Find a Trial helps patients search for active studies.
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Common questions about parkinson's disease clinical trials
Who can participate in Parkinson's disease clinical trials?
Eligibility criteria vary greatly by study, often including factors like age, disease stage, and overall health. Researchers carefully define these criteria to ensure patient safety and collect relevant data. Information on specific criteria is available on ClinicalTrials.gov.
What are the different phases of clinical trials for Parkinson's disease?
Clinical trials typically progress through phases 1, 2, and 3, each with different goals, such as testing safety, effectiveness, and comparing new treatments to existing ones. Phase 4 studies occur after a treatment is approved. These phases help ensure new therapies are thoroughly evaluated.
What are some current research directions for Parkinson's disease?
Current research for Parkinson's disease focuses on understanding disease mechanisms, developing neuroprotective therapies, and improving symptom management. Studies explore gene therapies, immunotherapies, and novel drug targets. Data from ClinicalTrials.gov and NIH RePORTER show diverse research efforts.
What types of interventions are studied in Parkinson's disease trials?
Interventions in Parkinson's disease trials include new medications to manage motor and non-motor symptoms, deep brain stimulation (DBS), and various rehabilitation therapies. Researchers also study lifestyle interventions and investigational biologics. These studies aim to improve patient quality of life.
Are biomarkers important in Parkinson's disease clinical trials?
Yes, biomarkers are crucial in Parkinson's disease research for early diagnosis, tracking disease progression, and assessing treatment response. Researchers are investigating various biomarkers, including genetic markers, imaging findings, and biological molecules in fluids. This helps personalize and optimize trial design.
Do clinical trials for Parkinson's disease cost money to participate?
Generally, study-related medical care, tests, and investigational treatments in clinical trials are provided at no cost to participants. However, patients may be responsible for routine medical care not related to the trial, travel, or other personal expenses.
What might prevent someone from joining a Parkinson's disease trial?
Common exclusion criteria for Parkinson's disease trials can include certain co-existing medical conditions, specific medications, or a history of other neurological disorders. These criteria help ensure participant safety and the integrity of study results. Details are always provided in the study protocol.
What are potential benefits and risks of participating in a Parkinson's disease trial?
Potential benefits include access to new treatments and contributing to medical knowledge. Risks can involve side effects from investigational therapies or the need for frequent study visits. All participants receive detailed information about potential risks and benefits before deciding to join.
How to find a parkinson's disease trial that fits you
- Describe your parkinson's disease situation in detail — stage if applicable, prior treatments, age, and other relevant conditions.
- Use the location filter (worldwide, US, US & Canada, Europe) to narrow to trials near you.
- Review each trial's eligibility criteria carefully. Save 2–5 candidates with their NCT numbers.
- Discuss with your treating clinician before contacting the research site.
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