Creating new technologies to better manage pain during and after surgery

Developing Active Stimulation and Monitoring Technologies to Optimize Pain and Nociception Management During Regional Anesthesia, General Anesthesia, and Post-Operative Care

['FUNDING_OTHER'] · PASCALL SYSTEMS, INCORPORATED · NIH-11160369

This study is testing new ways to help doctors better manage pain during and after surgery, especially for patients getting regional anesthesia, so they can provide more personalized care and help prevent long-term pain and reliance on pain medications.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorPASCALL SYSTEMS, INCORPORATED (nih funded)
Locations1 site (Boston, UNITED STATES)
Trial IDNIH-11160369 on ClinicalTrials.gov

What this research studies

This research focuses on developing innovative technologies to monitor and manage pain during surgical procedures and in the post-operative period. By utilizing event-related potentials (ERPs), the project aims to provide anesthesiologists with real-time data on the effectiveness of pain management strategies, particularly in patients receiving regional anesthesia. This approach seeks to reduce the reliance on guesswork in pain management, ultimately improving patient outcomes and reducing the risk of chronic pain and opioid dependence. The technology will assess pain responses to stimuli, allowing for more tailored analgesic therapies.

Who could benefit from this research

Good fit: Ideal candidates for this research include patients undergoing surgical procedures that require anesthesia, particularly those at risk for acute post-operative pain.

Not a fit: Patients who are not undergoing surgery or those who do not require anesthesia may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective pain management strategies, reducing the incidence of chronic pain and opioid dependence in surgical patients.

How similar studies have performed: While the approach of using ERPs for pain assessment is innovative, similar technologies have shown promise in other areas of pain management, indicating potential for success.

Where this research is happening

Boston, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.