Condition

Pancreatic Neoplasms clinical trials and research

• 40Clinical trials
• 19Countries

Newest Pancreatic Neoplasms clinical trials

All recruiting trials (40)

• Energy needs after pancreatic surgery: measuring metabolism to guide nutrition

  This study tests how much energy patients need after pancreatic surgery and compares direct measurements with common estimating methods to see if standard formulas are accurate.

  Recruiting Evangelismos Hospital · Athens, Attica · NCT07703813

• Liquid biopsy biomarkers to detect and monitor pancreatic cancer

  Researchers test blood-based microRNA signals to see if they can identify pancreatic cancer risk or early disease in people with familial or hereditary risk or mucinous cysts.

  Recruiting Università Vita-Salute San Raffaele · Milan, MI · NCT07700992

• Indocyanine green–guided laparoscopic distal pancreatectomy vs standard approach for pancreatic body/tail lesions

  This trial tests whether using indocyanine green (ICG) fluorescence during laparoscopic distal pancreatectomy helps surgeons protect blood flow and structures, compared with the standard approach, in adults with pancreatic body or tail tumors.

  Recruiting Alexandria University · Alexandria · NCT07656571

• Pancreatic Surgery and New Diabetes Risk in Adults without Diabetes

  This study tests whether removing part or all of the pancreas during surgery affects blood sugar control and metabolism in adults who did not have diabetes before the operation.

  Recruiting Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Rome · NCT07608055

• Pancreatic Cancer Screen Test in Japan Using the Enzeavour Blood Assay

  This nationwide screening study in Japan tests the Enzeavour Pancreatic Cancer blood test in about 10,000 asymptomatic adults to see if it can help detect pancreatic cancer early.

  Recruiting at 69 sites Cosomil, Inc. · Nagakute, Aichi-ken and 68 other locations · NCT07605819

• NEO-Match nanomechanical testing of pancreatic tumor samples

  This will test whether the NEO-Match® nanomechanical test on biopsy tissue can help predict response to pre-surgery treatment and detect cancer in people with suspected pancreatic tumors.

  Recruiting Artidis Ag · Tampa, Florida · NCT07542041

• Sodium bicarbonate, NASOX chemotherapy, and PD-1 immunotherapy delivered directly into the liver for pancreatic cancer metastases.

  This trial tests whether injecting sodium bicarbonate, a NASOX chemotherapy combination, and a PD-1 immune drug directly into the liver can help people whose pancreatic cancer has spread to the liver live longer.

  Recruiting Phase 2 Ruijin Hospital · Shanghai, Shanghai Municipality · NCT07504471

• Total pancreatectomy with islet transplantation for high-risk periampullary pancreatic tumors

  This study tests whether adults with periampullary tumors who are at high risk of pancreatic fistula after surgery can safely undergo total pancreatectomy with islet autotransplantation as an alternative approach.

  Recruiting Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · Baltimore, Maryland · NCT07360119

• Three-day discharge after distal pancreatectomy feasibility and effectiveness

  This study tests whether selected patients can go home 3 days after a minimally invasive distal pancreatectomy and still do well.

  Recruiting IRCCS San Raffaele · Milan · NCT07095621

• High-sensitivity blood test to detect and monitor multiple cancers

  This study will test a high-sensitivity blood test that looks for tumor DNA to detect and follow several common cancers in adults with those cancers or people having routine health screenings.

  Recruiting Yonsei University · Seoul · NCT07035587

• Comparing general anesthesia to combined anesthesia during pancreatic surgery

  This study is testing whether using general anesthesia alone or combined with an epidural is better for people having pancreatic surgery, focusing on how it affects blood pressure and other related issues during and after the operation.

  Recruiting Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran · Mexico City, Mexico City · NCT06953193

• Laparoscopic versus robot-assisted left-sided pancreas removal for benign and premalignant lesions

  This trial will randomize adults needing elective left-sided pancreas removal for benign or premalignant lesions to laparoscopic or robot-assisted minimally invasive surgery to see if one approach leads to faster recovery and fewer complications.

  Recruiting Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · Amsterdam · NCT06939023

• Tamoxifen treatment for advanced pancreatic tumors

  This study is testing if tamoxifen can help people with advanced pancreatic tumors that can't be removed or have spread, especially for those with hormone receptor-positive tumors.

  Recruiting Phase 2 Fudan University · Shanghai · NCT06914674

• Anti-mesothelin TNhYP218 CAR T cell therapy for mesothelin-expressing solid tumors

  This treatment will test whether a person's own engineered CAR T cells that target mesothelin can help adults with mesothelin-expressing solid tumors, including mesothelioma, that have returned or spread after standard therapy.

  Recruiting Phase 1 National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT06885697

• Combining TQB2868 injection, Anlotinib, and chemotherapy for treating metastatic pancreatic cancer

  This study is testing a new combination of TQB2868 injection, Anlotinib, and chemotherapy to see if it can help people with metastatic pancreatic cancer feel better and live longer.

  Recruiting at 2 sites Phase 2 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. · Zhengzhou, Henan and 6 other locations · NCT06767813

• KRAS neoantigen mRNA vaccine for patients with KRAS-mutated solid tumors

  This study is testing a new mRNA vaccine for patients with advanced solid tumors that have KRAS mutations to see if it can help them when used alone or with another treatment.

  Recruiting Early Phase 1 Ruijin Hospital · Shanghai · NCT06577532

• Cadonilimab with S-1 or Capecitabine for advanced pancreatic cancer

  This study is testing if a new combination of Cadonilimab with either S-1 or capecitabine can help people with advanced pancreatic cancer who have already tried other treatments.

  Recruiting Phase 2 Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT06532617

• Early detection of pancreatic cancer using exosome-based biomarkers

  This study is testing a new way to find pancreatic cancer early by looking at tiny particles in the blood that carry specific markers.

  Recruiting at 11 sites City of Hope Medical Center · Phoenix, Arizona and 12 other locations · NCT06388967

• Testing UCB4594 for advanced cancer treatment

  This study is testing a new drug called UCB4594 to see if it can help treat advanced cancer by targeting a specific protein on cancer cells.

  Recruiting at 3 sites Phase 1/2 Cancer Research UK · London and 3 other locations · NCT06380816

• Evaluating HTL0039732 for Advanced Solid Tumours

  This study is testing a new drug called HTL0039732, alone and with another treatment, to see if it can help people with advanced solid tumors by boosting their immune response against cancer.

  Recruiting at 6 sites Phase 1/2 Cancer Research UK · Cambridge and 5 other locations · NCT05944237

• Personalized cancer treatment for pancreatic cancer patients

  This study is testing if personalized cancer treatments based on tumor testing can help adults with pancreatic cancer respond better to therapy and improve their survival.

  Recruiting Medical College of Wisconsin · Milwaukee, Wisconsin · NCT05914987

• Developing a diagnostic model for pancreatic cystic tumors using fluid samples

  This study is testing if analyzing fluid samples from patients with pancreatic cystic tumors can help doctors tell the difference between harmless and harmful tumors.

  Recruiting Changhai Hospital · Shanghai, Shanghai Municipality · NCT05737953

• Early detection of pancreatic cancer using a blood test

  This study is testing a new blood test to see if it can help find pancreatic cancer earlier in people who are at high risk or show signs of the disease.

  Recruiting Biological Dynamics · San Diego, California · NCT05625529

• Combining surufatinib and camrelizumab with chemotherapy for advanced pancreatic cancer

  This study is testing a new combination of treatments for people with advanced pancreatic cancer to see if it works better than the standard options.

  Recruiting Phase 1/2 Chinese PLA General Hospital · Beijing · NCT05218889

• Imaging solid tumors using a new tracer called 68Ga-FAPI

  This study is testing a new imaging method using a special tracer to see if it can help doctors better detect certain types of cancer in patients who are having surgery.

  Recruiting Phase 1 Karolinska University Hospital · Stockholm · NCT05172310

• Pooling clinical experiences of patients treated with Lutetium-177 in Spain

  This study looks at how well Lutetium-177 works and how safe it is for patients with certain types of tumors in Spain by collecting information from their medical records.

  Recruiting at 11 sites Sociedad Española de Medicina Nuclear e Imagen Molecular · Santiago de Compostela, A Coruña and 19 other locations · NCT04949282

• Understanding pancreatic cysts and their risks

  This study is trying to understand pancreatic cysts better to help doctors tell which ones are harmless and which ones might be dangerous, so patients can avoid unnecessary tests and surgeries.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT04473794

• Investigating microRNA for diagnosing and treating pancreatic cancer

  This study is testing whether certain tiny molecules in the blood can help doctors diagnose pancreatic cancer earlier and see how well treatments are working for patients.

  Recruiting Nuvance Health · Norwalk, Connecticut · NCT04406831

• Finding blood-measurable protein and metabolite markers for pancreatic cancer using biopsy rinse samples

  This project will try whether proteins and small molecules recovered from the fluid used to rinse fine-needle biopsy samples can identify pancreatic cancer in people with a suspicious pancreatic mass.

  Recruiting University Hospital, Montpellier · Montpellier, Montpellier · NCT04370574

• Registry for pancreatic cysts at UCSF

  This study is setting up a registry to track patients with pancreatic cysts to see how these cysts change over time and to help doctors make better treatment decisions.

  Recruiting University of California, San Francisco · San Francisco, California · NCT04291651

• T cell therapy targeting KRAS G12V mutation for advanced pancreatic cancer

  This study is testing a new T cell therapy that uses patients' own immune cells to target a specific mutation in advanced pancreatic cancer to see if it can help them fight the disease.

  Recruiting Phase 1/2 Changhai Hospital · Shanghai · NCT04146298

• Evaluating the impact of MR-guided radiation therapy on cancer treatment outcomes

  This study is testing how using a special type of radiation therapy with real-time imaging can improve treatment results and quality of life for adults with cancer.

  Recruiting at 14 sites UMC Utrecht · Pittsburgh, Pennsylvania and 17 other locations · NCT04075305

• Evaluating tumor types in pancreatic cancer patients receiving FOLFIRINOX treatment

  This study is testing how different types of pancreatic cancer respond to the chemotherapy FOLFIRINOX before surgery to see if it helps make the tumors easier to remove.

  Recruiting Phase 2 UNC Lineberger Comprehensive Cancer Center · Chapel Hill, North Carolina · NCT03977233

• Screening for pancreatic cancer in people with new or worsening diabetes

  This study is testing if people over 50 with new or worsening diabetes might have pancreatic cancer and will use imaging and blood samples to look for early signs of the disease.

  Recruiting Nuvance Health · New Haven, Connecticut and 1 other locations · NCT03937453

• Registry for patients with pancreatic diseases

  This study is collecting health information from people with pancreatic diseases to help improve understanding and treatment options for these conditions.

  Recruiting Azienda Ospedaliera Universitaria Integrata Verona · Verona · NCT03807687

• Screening for pancreatic cancer in high-risk individuals

  This study is testing whether regular MRI scans and blood samples can help find pancreatic cancer early in people who have a strong family history or genetic risk for the disease.

  Recruiting Nuvance Health · Norwalk, Connecticut · NCT03250078

• EUS-guided radiofrequency ablation for pancreatic tumors

  This study is testing a new heat-based treatment for pancreatic tumors in patients who can't have surgery to see if it is safe and effective.

  Recruiting Chinese University of Hong Kong · Hong Kong · NCT03218345

• Database for patients who had surgery for pancreatic cancer

  This study is collecting detailed medical information from patients who had surgery for pancreatic cancer to help improve treatment and understand outcomes better.

  Recruiting Institut Paoli-Calmettes · Marseille, Bouches du Rhone · NCT02871336

• Database of patients with pancreatic neoplasms

  This study is creating a database to collect information from patients with pancreatic tumors to help researchers understand their condition better and improve future treatments.

  Recruiting Institut Paoli-Calmettes · Marseille, Bouches du Rhone · NCT02869581

• Collecting samples and studying the natural history of malignant mesothelioma

  This study is collecting tissue samples from people with malignant mesothelioma and certain other cancers to learn more about the disease and help improve future treatments.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT01950572

Related topics

Quick answers

How many Pancreatic Neoplasms clinical trials are recruiting right now?

40, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 19 countries. The most sites are in United States (14 trials), China (8 trials), Italy (5 trials), United Kingdom (3 trials), France (3 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 5, Phase 1/2: 4, Phase 1: 2, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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