Energy needs after pancreatic surgery: measuring metabolism to guide nutrition
Official title: Resting Energy Expenditure, Nutritional Intake, and Postoperative Outcomes in Patients Undergoing Total or Partial Pancreatectomy for Pancreatic Tumors: A Prospective Observational Cohort Study
Run by Evangelismos Hospital · NCT07703813 · Data updated 2026-11-12
This study tests how much energy patients need after pancreatic surgery and compares direct measurements with common estimating methods to see if standard formulas are accurate.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 75 Years |
| Sex | All |
| Enrollment | 150 (estimated) |
| Sponsor | Evangelismos Hospital Academic / other |
| Locations | 1 site (Athens, Attica) |
| Status | Recruiting |
| Started | January 10, 2017 |
| Main results expected | January 10, 2028 |
| Study ends | November 10, 2028 |
| Registry record updated | July 14, 2026 |
| Trial ID | NCT07703813 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 18–75 years scheduled for total or partial pancreatectomy (including Whipple) for pancreatic tumors who can tolerate a calorimetry measurement and consent to participate.
✕Probably not a fit
Patients who do not undergo post-surgical calorimetry measurements or have unique metabolic conditions may not benefit from refined energy targets.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This single-center, prospective observational cohort study enrolls adults undergoing total or partial pancreatectomy for pancreatic tumors. It directly measures resting energy expenditure using indirect calorimetry in the early postoperative period and compares these measurements with predictive equations and simple calorie targets. The study also documents postoperative nutrition routes (enteral, parenteral, or mixed), actual energy and protein intake relative to measured needs, diet-related symptoms, and clinical outcomes including complications and hospital readmission. Feeding decisions are made by treating teams and observed as part of routine care, not assigned by the protocol. Data are collected by trained clinical dietitians from direct measurements and medical records.
Why it matters
Potential benefit: If successful, the results could improve how nutrition is prescribed after pancreatic surgery by validating or refining energy targets when calorimetry is not available.
How similar studies have gone: prior work in other surgical populations suggests indirect calorimetry can improve accuracy of energy prescriptions, but data in pancreatic surgery are limited and this study extends that evidence in this specific group.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 18 years or older * Scheduled to undergo total or partial pancreatectomy (including pancreaticoduodenectomy/Whipple procedure or distal pancreatectomy) for a pancreatic tumor * Able to complete indirect calorimetry measurement by canopy or face mask for the required duration * Able to provide written informed consent Exclusion Criteria: * Age under 18 years, greater than 75 years * Pregnancy * Inability to tolerate the calorimetry canopy or mask for the duration required for a valid measurement * Unable or unwilling to provide informed consent * patients already on preoperative enteral nutrition or unable to feed orally preoperatively
Where it's running
-
Evaggelismos General Hospital
Athens, Attica, Greece Recruiting
Study contacts
- Study coordinator: Dimitrios Karagiannis, PhD
- Email: jimkar_d@yahoo.com
- Phone: 2132045035
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.