Collecting samples and studying the natural history of malignant mesothelioma

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on patients with malignant mesothelioma and other cancers that express mesothelin. It aims to acquire tissue samples to better understand the disease's natural history and improve future treatment options. Eligible participants include individuals aged 2 years and older with confirmed diagnoses of malignant mesothelioma or other specified cancers. The study will not involve any specific interventions but will gather valuable data through sample collection.

Why it matters

Who can join: the full rules

* INCLUSION CRITERIA:
* All participants \>= 2 years of age with malignant mesothelioma.
* All participants \>=18 years of age with thymic carcinoma, pancreatic or biliary adenocarcinoma or lung, gastric or ovarian cancers or other solid tumor known to express mesothelin.
* Confirmed pathological diagnosis is required
* Ability and willingness of participant to provide informed consent to participation.

EXCLUSION CRITERIA:

* Active symptomatic major organ disorder that would increase the risk of biopsy, including but not limited to ischemic heart disease, recent myocardial infarction, active congestive heart failure, pulmonary dysfunction.
* Pregnant women.
* Active concomitant medical or psychological illnesses that may increase the risk to the participant or in adult participants, inability to obtain informed consent, at the discretion of the principal investigator.

Where it's running

• National Institutes of Health Clinical Center
  Bethesda, Maryland, United States Recruiting

Study contacts

• Principal investigator: Raffit Hassan, M.D. — National Cancer Institute (NCI)
• Study coordinator: Cathy I Wagner, R.N.
• Email: cathy.wagner@nih.gov
• Phone: (240) 858-3159

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.