Condition

Newborn clinical trials and research

• 18Clinical trials
• 83NIH research projects
• 11Countries

Newest Newborn clinical trials

All recruiting trials (18)

• Dry Cord Care vs Alcohol Cord Care for Healthy Newborns

  This trial tests whether dry cord care or routine alcohol cord care is better for healthy newborns by looking at infection rates in the umbilical cord.

  Recruiting Chang Gung Memorial Hospital · New Taipei City, Taiwan · NCT07728058

• Breathing before breastfeeding to help moms of NICU babies

  This study tests whether pre-breastfeeding breathing exercises can reduce anxiety and improve well-being for mothers with babies in the NICU.

  Recruiting Inonu University · Elâzığ, Elâzığ · NCT07634445

• Co‑dodo crib use to improve maternal–newborn sleep and bonding in the maternity ward

  This study tests whether using a co‑dodo crib during the hospital postpartum stay helps full‑term, exclusively breastfeeding mothers and their newborns sleep better and bond more than a standard crib.

  Recruiting Centre Hospitalier Universitaire, Amiens · Amiens, Picardie · NCT07525830

• Does giving IV fluids to mothers before birth change how much a newborn loses weight in the first days?

  This project sees if the amount of IV fluids a mother receives before delivery affects weight loss in formula-fed newborns during their first two days of life.

  Recruiting Centre Hospitalier Universitaire, Amiens · Amiens, Picardie · NCT07243054

• Reducing heel‑prick pain and improving comfort in newborns with Buzzy or ShotBlocker

  This test tries whether using a small vibrating device (Buzzy) or a pressure device (ShotBlocker) before and after a heel prick can reduce pain and improve comfort for full‑term newborns.

  Recruiting Tarsus University · Mersin · NCT07081048

• NeoBellyBand abdominal support for premature infants on CPAP

  We will try the FDA-approved DandleLion NeoBellyBand on premature infants needing CPAP to see if it thickens their rectus abdominis muscle and helps them reach full oral feedings sooner.

  Recruiting University of Minnesota · Minneapolis, Minnesota · NCT07049900

• Using intranasal breast milk to help preterm infants

  This study is testing if giving breast milk through the nose can help preterm infants improve their brain health and feeding times.

  Recruiting Selcuk University · Konya · NCT06706115

• Monitoring vital signs of newborns using advanced wireless sensors

  This study is testing a new wireless sensor to see if it can safely and accurately monitor the vital signs of healthy newborns during their first two hours after birth compared to the traditional wired system.

  Recruiting at 2 sites McGill University Health Centre/Research Institute of the McGill University Health Centre · Londrina, Paraná and 4 other locations · NCT06693817

• Evaluating non-invasive ventilation methods for preterm infants with respiratory distress

  This study is testing different breathing support methods for premature babies with breathing problems to see which one helps them the best.

  Recruiting Alexandria University · Alexandria · NCT06550219

• Adjusting ventilator PEEP to improve lung compliance and heart function in preterm infants

  We will try changing the ventilator's PEEP settings in babies born before 34 weeks who need breathing support to see if the PEEP that gives the best lung compliance improves heart output and oxygen levels.

  Recruiting University of Alabama at Birmingham · Birmingham, Alabama · NCT06512935

• Using exosome microRNAs to identify metabolic bone disease in premature infants

  This study is trying to see if tiny particles in the blood of premature babies can help doctors spot a serious bone disease early on.

  Recruiting Hunan Children's Hospital · Changsha, Hunan · NCT06368154

• Evaluating infant crying as a predictor of neurodevelopment

  This study is trying to see if the sounds of crying from newborns can help predict how well they will develop by the time they are two years old.

  Recruiting Centre Hospitalier Universitaire de Saint Etienne · Saint-Etienne · NCT06332521

• Impact of chemical pollutants on infant sleep

  This study is testing how exposure to chemical pollutants affects the sleep patterns of infants under 6 months old to see if it impacts their development.

  Recruiting Centre Hospitalier Universitaire, Amiens · Amiens · NCT06268444

• Telemedicine for neonatal resuscitation in community hospitals

  This study tests if using video calls with neonatologists can help improve the care and health outcomes for newborns in community hospitals who need immediate medical attention.

  Recruiting at 34 sites Mayo Clinic · Anchorage, Alaska and 35 other locations · NCT06087224

• Caffeine treatment for late preterm infants with breathing difficulties

  This study tests if giving caffeine to late preterm infants with breathing problems can help them breathe better and shorten their hospital stay.

  Recruiting at 2 sites Phase 2/3 Ministry of Health, Saudi Arabia · Madinah, Medina Region and 1 other locations · NCT06026163

• Early genetic screening for critical illnesses in newborns

  This study is testing a new genetic screening program for newborns in China to see if it can help identify serious hereditary diseases early and improve their chances of survival.

  Recruiting Children's Hospital of Fudan University · Shanghai, Shanghai Municipality · NCT04905537

• Genetic testing of newborns in China

  This study is testing genetic testing on newborns in China to see if it can help identify inherited diseases early and improve treatment options for babies.

  Recruiting Children's Hospital of Fudan University · Shanghai, Shanghai Municipality · NCT03931707

• Monitoring brain blood flow and oxygen in premature infants

  This study is trying to see if monitoring blood flow and oxygen in the brains of premature infants with certain types of brain bleeding can help doctors understand how serious their condition is and how well treatments are working.

  Recruiting Boston Children's Hospital · Boston, Massachusetts and 2 other locations · NCT02601339

NIH-funded research (newest 40 of 83)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Adaptive e-learning and smartphones to improve newborn and child care in Tanzania

  A new program uses smart devices and tailored online learning to help frontline health workers in Mwanza, Tanzania provide better care for newborns and young children.

  NIH research Catholic University of Health and Allied Sciences Bugando · Mwanza, Tanzania U Rep · NIH-11629861

• NoviGuide for Newborn Care in Pakistan

  A small NIH grant to test a pocket-sized decision support tool for nurses and doctors to improve newborn care in Pakistan.

  NIH research Aga Khan University (Pakistan) · Karachi, Pakistan · NIH-11624823

• Newborn screening: using gene and metabolite data to refine true vs false positives

  A study using genetic and metabolomic data from newborn blood spots to better distinguish real metabolic disorders from false alarms.

  NIH research Yale University · New Haven, United States · NIH-11608554

• Evidence-based practices for managing neonatal hypothermia in newborn nurseries

  A doctor-led project will study how common newborn hypothermia affects babies in US nurseries and develop trusted guidelines to improve care.

  NIH research Kaiser Foundation Research Institute · Oakland, UNITED STATES · NIH-11607888

• Agricultural livelihoods to improve health for pregnant women with HIV in Kenya

  A pregnancy-starting program in Kenya tests whether helping families grow food and earn income can improve the health and nutrition of mothers and their babies, especially for women living with HIV.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11514204

• Agricultural livelihood support for pregnant women and newborns in Kenya

  Compares agricultural livelihood support to usual care to help pregnant women in Kenya—including those living with HIV—have better nutrition and healthier newborns.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11469757

• Genomic newborn screening: addressing big questions for babies and families

  This project looks at how to responsibly use genome sequencing for newborn screening and what it means for babies, families, and care systems.

  NIH research Boston Children's Hospital · Boston, United States · NIH-11455382

• ScreenPlus: A broader newborn screening program for early detection of multiple rare disorders

  This project tests a broader newborn screening panel for consented babies to detect additional rare, treatable conditions early and follow outcomes over time.

  NIH research Albert Einstein College of Medicine · Bronx, United States · NIH-11403977

• Motion-robust measurement of brain iron in newborns with advanced 3D MRI

  This project tests a faster, motion-tolerant MRI method to measure brain iron in newborns and young adults to better understand iron's role in brain development.

  NIH research Boston Children's Hospital · Boston, United States · NIH-11400031

• Air pollution and heat effects on pregnant women and young children in Zimbabwe

  This project will look at how air pollution and unusually hot weather affect the health of pregnant women, newborns, and children under 11 in Zimbabwe.

  NIH research Centre/sexual Hlth/hiv Aid Res/zimbabwe · Harare, Zimbabwe · NIH-11397924

• Air pollution and heat effects on pregnant women, newborns, and children in sub‑Saharan Africa

  This project looks at how air pollution and high temperatures affect the health of pregnant women, newborns, and children up to age 11 in sub‑Saharan Africa.

  NIH research Centre/sexual Hlth/hiv Aid Res/zimbabwe · Harare, Zimbabwe · NIH-11397921

• mHealth OAE: Simple newborn hearing screening for Kenya using a low-cost smartphone device

  A low-cost smartphone hearing test is being studied to help newborns in Kenya be screened for hearing loss early.

  NIH research University of Washington · Seattle, United States · NIH-11397331

• Improving newborn and child admission care in Mwanza with smartphone-based training for health workers

  This project uses smartphone lessons plus hands-on practice to help health workers give better care to newborns and young children admitted to hospitals in Mwanza, Tanzania.

  NIH research Stanford University · Stanford, United States · NIH-11392148

• Using smartphone adaptive training to improve newborn and child hospital care in Mwanza

  This project uses smartphone-based adaptive training to help health workers in Mwanza give better care to newborns and young children.

  NIH research Stanford University · Stanford, United States · NIH-11392144

• Neurodevelopmental outcomes in babies with CMV detected at birth

  This project follows newborns identified with congenital CMV to understand how the infection affects brain development and later learning and behavior.

  NIH research University of Minnesota · Minneapolis, United States · NIH-11391258

• Prenatal pollution exposure and newborn lung injury risk

  This research looks at whether chemicals from polluted sites during pregnancy make preterm newborns more likely to develop serious lung disease.

  NIH research Baylor College of Medicine · Houston, United States · NIH-11388581

• Enhancing newborn screening to better treat Krabbe, Pompe, and MPS I

  A study to improve how newborns are screened for Krabbe disease, Pompe disease, and MPS I so that babies who need treatment are identified faster and more accurately.

  NIH research State University of New York at Buffalo · Amherst, United States · NIH-11387708

• Optimal vasopressor choice for newborns with PPHN

  This study tests which vasopressor best supports blood flow and oxygenation in newborns with persistent pulmonary hypertension after birth.

  NIH research University of California at Davis · Davis, United States · NIH-11378190

• Smartphone hearing checks for newborns in Kenya

  This project tests a low-cost smartphone device to screen newborns and young infants for hearing loss at Kenyan clinics.

  NIH research University of Washington · Seattle, United States · NIH-11375372

• Newborn bloodspot biobank consent process to support research in Michigan hospitals

  A study to improve how parents and caregivers give permission for using newborn bloodspots in research to build a more representative biobank.

  NIH research Utah State Higher Education System--University of Utah · Salt Lake City, United States · NIH-11374133

• Newborn sequencing with rapid, affordable protein tagging to map amino-acid changes

  A new method will quickly map all possible amino-acid changes in proteins to help interpret newborn genome data for faster, more accurate diagnoses.

  NIH research University of Washington · Seattle, United States · NIH-11370044

• Effects of chronic low oxygen on brain blood flow control in newborns

  A study in newborns and animal models will explore how chronic low oxygen affects the brain’s ability to keep blood flow steady, which is crucial for preventing brain injuries.

  NIH research Loma Linda University · Loma Linda, UNITED STATES · NIH-11341894

• Newborn Iron Deficiency and its Long-Term Brain Effects

  A study exploring how iron deficiency in early life can affect a child’s brain development and long-term cognitive and emotional health.

  NIH research University of Minnesota · Minneapolis, United States · NIH-11324638

• How a mother's antibodies affect newborn flu vaccine protection

  This project looks at how antibodies passed from pregnant people to their babies change how infants respond to flu vaccination so newborns can be better protected.

  NIH research Wake Forest University Health Sciences · Winston-Salem, United States · NIH-11322702

• How a mother's triglyceride levels influence newborn body and liver fat in pregnancies with obesity

  This project looks at whether higher maternal blood triglycerides during pregnancy are linked to more body and liver fat in newborns of people with overweight or obesity.

  NIH research University of Colorado Denver · Aurora, UNITED STATES · NIH-11312645

• Placenta genes and newborn metabolism linked to childhood asthma

  This research looks at how gene activity in the placenta and metabolic markers in newborns relate to the risk of childhood asthma.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-11310156

• NoviGuide for Newborn Care in Pakistan

  A phone- or computer-based decision tool helps frontline nurses and doctors make better newborn care choices in Pakistan.

  NIH research Aga Khan University (Pakistan) · Karachi, Pakistan · NIH-11307182

• Improving newborn genome screening to find urea cycle disorders

  This project improves how newborn genome sequencing finds urea cycle disorders in babies by making genetic variant results easier to interpret.

  NIH research Pacific Northwest Research Institute · Seattle, United States · NIH-11285457

• Faster newborn heel‑prick blood test to find treatable genetic conditions

  This project is building a quicker dried‑blood‑spot test to detect many treatable genetic diseases in newborn babies.

  NIH research Seattle Children's Hospital · Seattle, United States · NIH-11283949

• Farming support for pregnant women in rural Kenya to improve mother and newborn nutrition

  This project offers farming support to pregnant women in rural Kenya to try to improve mothers' nutrition and newborns' health.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11261244

• How newborn olfactory neurons integrate into the brain's circuits

  This study is looking at how new smell-related brain cells grow and connect in both healthy and recovering brains, which could help improve treatments for people with brain injuries or conditions that affect their sense of smell.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11221046

• Detecting Metachromatic Leukodystrophy in Newborns

  This study is testing a new way to check newborns for Metachromatic Leukodystrophy (MLD) and similar conditions right after they are born, so that if they have it, they can get help early and have a better chance at a healthier life.

  NIH research Nysdoh/health Research, INC. · Menands, United States · NIH-11199664

• Detecting serious health conditions in newborns early on

  This study is all about making sure that newborns are checked for serious health conditions early on, so they can get the help they need right away, even if they seem healthy at first.

  NIH research Emory University · Atlanta, United States · NIH-11196157

• Tailored smartphone learning to improve newborn and child admission care in Mwanza, Tanzania

  This project gives nurses and doctors in Mwanza personalized smartphone lessons plus hands-on practice so newborns and young children get better care when admitted to hospitals.

  NIH research Stanford University · Stanford, United States · NIH-11194446

• ScreenPlus: Expanded newborn screening to find more rare conditions

  This program offers expanded blood-spot screening for newborns in New York to find more rare conditions early and follow affected children over time.

  NIH research Albert Einstein College of Medicine · Bronx, United States · NIH-11191551

• Improving newborn screening for cystic fibrosis to be more accurate and fair

  Develops and compares newborn screening methods to improve detection of cystic fibrosis in newborns, with attention to fairness for African American babies.

  NIH research University of Alabama in Tuscaloosa · Tuscaloosa, United States · NIH-11190804

• How air pollution and heat affect pregnant women, newborns, and young children in sub‑Saharan Africa

  This project looks at how air pollution and heat impact the health of pregnant women, newborns, and children under 11 in parts of sub‑Saharan Africa.

  NIH research Centre/sexual Hlth/hiv Aid Res/zimbabwe · Harare, Zimbabwe · NIH-11179193

• Improving Newborn Screening with Whole Genome Sequencing

  This project aims to make newborn screening more accurate by better understanding genetic changes found through whole genome sequencing.

  NIH research University of Washington · Seattle, United States · NIH-11176114

• Newborn tests to find and predict severity of inherited enzyme disorders

  This project creates blood‑spot tests to detect certain inherited enzyme disorders in newborns and help predict how serious they might become.

  NIH research University of Washington · Seattle, United States · NIH-11170704

• Investigating the effects of iron deficiency in newborns

  This study is looking at how not getting enough iron early in life can affect how babies and young kids think and learn, and it aims to find ways to help those who might be struggling because of it.

  NIH research University of Minnesota · Minneapolis, United States · NIH-11136375

Related topics

Quick answers

How many Newborn clinical trials are recruiting right now?

18, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 11 countries. The most sites are in France (4 trials), United States (4 trials), China (3 trials), Turkey (Türkiye) (3 trials), Canada (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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