Air pollution and heat effects on pregnant women, newborns, and children in sub‑Saharan Africa

CHaracterizing Effects of Air Quality In Maternal, Newborn and Child Health: The CHEAQI-MNCH Research Project

NIH-funded research Centre/sexual Hlth/hiv Aid Res/zimbabwe · NIH-11397921

This project looks at how air pollution and high temperatures affect the health of pregnant women, newborns, and children up to age 11 in sub‑Saharan Africa.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionCentre/sexual Hlth/hiv Aid Res/zimbabwe NIH-funded
Lab location1 site (Harare, Zimbabwe)
Project IDNIH-11397921 on NIH RePORTER

What this research studies

You would be followed during pregnancy and your child tracked after birth while the team measures air pollution and heat in your community. The project combines local air sensors, satellite data, and questionnaires about housing, work, and healthcare access to estimate each person’s exposure. Researchers will link those exposure estimates to outcomes like miscarriage, stillbirth, preterm birth, low birth weight, and preeclampsia. The aim is to find who is most at risk and what data are needed to guide health responses and protective actions.

Who could benefit from this research

Good fit: Ideal participants are pregnant women and caregivers of children under 11 who live in the study areas in Harare, Zimbabwe or similar sub‑Saharan African communities, especially where air quality or heat exposure is high.

Not a fit: People living outside the study region or those without relevant exposure to air pollution or heat are unlikely to gain direct benefit from participating.

Why it matters

Potential benefit: If successful, the findings could guide programs to protect pregnant women and young children from pollution and heat, lowering rates of preterm birth and low birth weight.

How similar studies have performed: Other studies in non‑African settings have linked air pollution and heat to worse birth outcomes, but applying these methods in sub‑Saharan Africa is relatively new because local data are limited.

Where this research is happening

Harare, Zimbabwe

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.