Condition

Genetic Predisposition to Disease clinical trials and research

• 17Clinical trials
• 8Countries

Newest Genetic Predisposition to Disease clinical trials

All recruiting trials (17)

• Sirolimus for ApoE4 Carriers: Testing Brain Blood Flow in Women 45-65

  Researchers will test whether sirolimus can improve brain blood flow in healthy ApoE4-positive women ages 45 to 65 compared with a placebo.

  Recruiting Phase 1 University of Missouri-Columbia · Columbia, Missouri · NCT07728175

• Germline testing for inherited risk of myeloid blood cancers

  This research will test whether a germline genetic test (MyeloGen Gene Panel) can find inherited changes linked to myeloid blood cancers in adults who have been diagnosed.

  Recruiting Dana-Farber Cancer Institute · Boston, Massachusetts · NCT07112287

• Examining the role of vaginal microbiome in ovarian cancer detection

  This study is trying to see if the bacteria in the vagina can help detect ovarian cancer earlier by comparing samples from healthy women and those at higher risk or already diagnosed.

  Recruiting Abramson Cancer Center at Penn Medicine · Philadelphia, Pennsylvania · NCT06962059

• A network for advancing genomics research and improving health

  This study is testing how sharing genetic information from patients can help doctors better understand diseases and improve treatments for everyone involved.

  Recruiting at 14 sites Helix, Inc · Fort Wayne, Indiana and 13 other locations · NCT06057181

• Using genetic profiling to improve cancer treatment

  This study is testing if using genetic information can help doctors choose better treatments for cancer patients based on their specific tumor characteristics.

  Recruiting Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Rome · NCT06020625

• Molecular profiling and drug testing for pediatric acute myeloid leukemia

  This study is trying to learn more about pediatric acute myeloid leukemia by looking at patients' cells to find out why some treatments don’t work and to test new drug options for kids and young adults with this cancer.

  Recruiting at 28 sites Assistance Publique - Hôpitaux de Paris · Amiens and 27 other locations · NCT05772559

• Assessing cardiovascular disease risks in the Ballana population

  This study is trying to see how common heart disease is in the Ballana community in Egypt and what factors might increase the risk over the next 30 years.

  Recruiting Magdi Yacoub Heart Foundation · Aswān · NCT05661318

• Genetic analysis of healthy Egyptians to understand heart disease

  This study is trying to understand the genetic differences in healthy Egyptians to help identify what might lead to heart disease in people with inherited heart conditions.

  Recruiting Magdi Yacoub Heart Foundation · Aswān · NCT05661305

• Evaluating genetic risk and screening for prostate cancer

  This study is testing if prostate MRIs can help men at high genetic risk for prostate cancer find aggressive forms of the disease earlier.

  Recruiting Massachusetts General Hospital · Boston, Massachusetts · NCT05129605

• Exploring the link between breast microbiome and implant infections after mastectomy

  This study tests if the bacteria in the breast can affect the chances of getting infections after mastectomy and implant surgery, comparing those who get antibiotics with those who don’t.

  Recruiting Phase 2 University of California, San Francisco · San Francisco, California · NCT05020574

• Testing for cancer risk genes in children with newly diagnosed cancer

  This study is testing whether a family-based genetic test can help find cancer risk genes in children and teens who have just been diagnosed with cancer.

  Recruiting at 3 sites Sydney Children's Hospitals Network · Newcastle, New South Wales and 2 other locations · NCT04903782

• Genome-based management for patients with unclear genetic diseases

  This study is testing if using whole genome sequencing as a first step can help find the causes of unclear genetic diseases in about 12,000 patients.

  Recruiting University Hospital Tuebingen · Tübingen · NCT04760522

• Assessing genetic and molecular profiles in health and disease in the Czech population

  This study is trying to gather genetic and health information from 10,000 people in the Czech Republic, both healthy and those with diseases, to help better understand health issues in the region.

  Recruiting The Institute of Molecular and Translational Medicine, Czech Republic · Olomouc · NCT04427163

• Investigating genetic causes in twins with different health outcomes

  This study is trying to find out what genetic differences might explain why one twin is healthy while the other has an undiagnosed disease.

  Recruiting University Hospital Tuebingen · Tübingen · NCT04046796

• Genetic testing of newborns in China

  This study is testing genetic testing on newborns in China to see if it can help identify inherited diseases early and improve treatment options for babies.

  Recruiting Children's Hospital of Fudan University · Shanghai, Shanghai Municipality · NCT03931707

• Identifying blood markers for early pancreatic cancer

  This study is trying to find specific blood markers that can help detect early pancreatic cancer in people who are at higher risk.

  Recruiting University of Nebraska · Omaha, Nebraska · NCT03568630

• Identifying genetic factors affecting recovery after heart surgery

  This study is trying to find out if certain genes can help predict how well patients recover after heart surgery and if they might face complications.

  Recruiting Brigham and Women's Hospital · Boston, Massachusetts and 2 other locations · NCT01258231

Related topics

Quick answers

How many Genetic Predisposition to Disease clinical trials are recruiting right now?

17, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 8 countries. The most sites are in United States (8 trials), Germany (2 trials), Egypt (2 trials), Australia (1 trial), China (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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