Does giving IV fluids to mothers before birth change how much a newborn loses weight in the first days?
Official title: Impact of Prepartum Intravenous Fluid Intake on Newborn Weight Loss in the First Days of Life
Run by Centre Hospitalier Universitaire, Amiens · NCT07243054 · Data updated 2026-11-12
This project sees if the amount of IV fluids a mother receives before delivery affects weight loss in formula-fed newborns during their first two days of life.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | Women only |
| Enrollment | 200 (estimated) |
| Sponsor | Centre Hospitalier Universitaire, Amiens Academic / other |
| Locations | 1 site (Amiens, Picardie) |
| Status | Recruiting |
| Started | March 1, 2025 |
| Main results expected | November 2025 |
| Study ends | November 2025 |
| Registry record updated | November 21, 2025 |
| Trial ID | NCT07243054 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are mothers aged 18 or older who delivered a full-term singleton at CHU Amiens and whose infants were exclusively formula-fed in the maternity ward for the first two days.
✕Probably not a fit
Patients who are breastfeeding, had preterm or multiple births, required maternal hemodynamic support before delivery, or whose infants have renal disease or cleft conditions are unlikely to benefit from these specific findings.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a retrospective, observational single-center review using medical records from CHU Amiens to explore links between maternal prepartum intravenous fluid administration during labor and early neonatal weight changes. The analysis included mothers aged 18 and older with full-term (≥37 weeks), singleton deliveries whose infants were exclusively formula-fed in the maternity ward, with daily newborn weights recorded for the first two days. Records with incomplete data, mixed or exclusive breastfeeding, maternal hemodynamic disorders requiring targeted filling, or infants with renal/uropathy or cleft conditions were excluded. Investigators compared maternal fluid volumes given before delivery with newborn weight loss and early signs such as jaundice or respiratory distress.
Why it matters
Potential benefit: If a clear link is found, clinicians could adjust pre-delivery IV fluid practices or newborn assessment timing to reduce misleading early weight loss and related complications like jaundice.
How similar studies have gone: Previous observational work has suggested maternal intrapartum IV fluids can transiently affect neonatal weight change, but results are mixed and the effect remains incompletely settled.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Full-term delivery (≥37+0 SA) * Singleton pregnancy * Mother over 18 years of age * Infant formula feeding exclusively in the maternity ward for the first 2 days Exclusion Criteria: * Mother under guardianship * Mother who does not understand French * Mother objecting to her personal data being reused for research purposes * Incomplete or incorrectly completed patient medical record * Mixed or exclusive breastfeeding * Mother presenting a hemodynamic disorder in the 12 hours preceding delivery, requiring a filling specifically for this reason * Child with renal pathology or uropathy * Children with cleft lip, palate or labio-palate
Where it's running
-
CHU Amiens Picardie
Amiens, Picardie, France Recruiting
Study contacts
- Study coordinator: Pierre Tourneux, Pr
- Email: Tourneux.Pierre@chu-amiens.fr
- Phone: 33+3 22 08 76 04
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.