How air pollution and heat affect pregnant women, newborns, and young children in sub‑Saharan Africa

CHaracterizing Effects of Air Quality In Maternal, Newborn and Child Health: The CHEAQI-MNCH Research Project

NIH-funded research Centre/sexual Hlth/hiv Aid Res/zimbabwe · NIH-11179193

This project looks at how air pollution and heat impact the health of pregnant women, newborns, and children under 11 in parts of sub‑Saharan Africa.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionCentre/sexual Hlth/hiv Aid Res/zimbabwe NIH-funded
Lab location1 site (Harare, Zimbabwe)
Project IDNIH-11179193 on NIH RePORTER

What this research studies

This work follows pregnant women and young children in Zimbabwe and nearby communities to link air pollution and heat events with outcomes like miscarriage, stillbirth, preterm birth, low birth weight, and preeclampsia. The team will combine ground air‑quality sensors, satellite and weather data, and health records or clinic visits to estimate individual and community exposures. Advanced data science methods will be used to identify which families and neighborhoods are most at risk and how poverty, food insecurity, and access to care change those risks. Results are intended to help health services target protections and inform policies to reduce pollution‑related harm.

Who could benefit from this research

Good fit: Pregnant women and caregivers of children under 11 living in urban or peri‑urban areas of Zimbabwe or other participating sub‑Saharan African sites would be the likely candidates for participation.

Not a fit: People who do not live in the study areas or who are not pregnant and do not care for young children are unlikely to get direct benefits from participating.

Why it matters

Potential benefit: If successful, this work could help identify high‑risk mothers and children so local health programs and policies can better prevent pollution‑related pregnancy and childhood harms.

How similar studies have performed: Previous studies in other regions have linked air pollution and heat to poor birth outcomes, but comparable studies in African populations are limited, so this work builds on suggestive evidence.

Where this research is happening

Harare, Zimbabwe

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.