Condition

Memory Impairment clinical trials and research

• 15Clinical trials
• 13NIH research projects
• 7Countries

Newest Memory Impairment clinical trials

All recruiting trials (15)

• Mobile reminder app to help people with chronic disease and memory loss stick to their meds

  This study tests whether a smartphone reminder app can improve how well adults with chronic diseases and memory impairment take their prescribed medications.

  Recruiting at 2 sites Mansoura University · Gamasa, Dakahlia Governorate and 1 other locations · NCT07718334

• Following memory decline in Alzheimer disease

  This project will use 7T MRI, EEG, blood and stool samples, and memory tests to see if they can track memory decline in people over 55 with Alzheimer's disease or mild cognitive impairment.

  Recruiting Norwegian University of Science and Technology · Trondheim, Trønderlag · NCT07118137

• HOBSCOTCH-MS: Home-based telehealth cognitive coaching for people with multiple sclerosis

  This program will test whether a home-based telehealth cognitive coaching program (HOBSCOTCH-MS) can improve thinking, memory, and quality of life for people with MS and reduce caregiver burden.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT06951919

• Home-based self-management and cognitive training for brain tumor survivors

  This trial will try a home-based cognitive coaching program to see if it improves thinking and quality of life for adults who survived non-glioblastoma brain tumors, with optional caregiver participation.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT06930846

• Investigating biomarkers related to Alzheimer's disease and cognitive impairment

  This study is trying to see how blood tests and brain scans relate to Alzheimer's disease and memory issues in older adults aged 60 to 90.

  Recruiting at 23 sites GAP Innovations, PBC · Atlantis, Florida and 25 other locations · NCT06584357

• Improving attention in military personnel with mild traumatic brain injury using brain stimulation and cognitive training

  This study is testing a new way to help Active Duty Service Members and Veterans with mild traumatic brain injury improve their attention by combining brain stimulation with cognitive training.

  Recruiting at 2 sites United States Naval Medical Center, San Diego · San Diego, California and 1 other locations · NCT06413173

• Using lithium to prevent cognitive decline after brain radiotherapy in children

  This study is testing if taking lithium can help prevent memory and thinking problems in children who have survived brain tumors and received radiation therapy.

  Recruiting Phase 2 Region Stockholm · Solna, Stockholm County and 1 other locations · NCT06051240

• Improving memory and well-being in older adults with sleep issues

  This study is testing if a new memory support program can help older adults with sleep problems feel better and remember things more clearly when combined with a standard sleep treatment.

  Recruiting University of California, Berkeley · Berkeley, California · NCT05986604

• Aerobic exercise program for older adults with mild cognitive impairment

  This study is testing if a 6-month aerobic exercise program can help older adults with mild cognitive impairment or early Alzheimer's improve their brain health and fitness.

  Recruiting Arizona State University · Phoenix, Arizona · NCT05877196

• Comparing two therapies for insomnia in veterans with traumatic brain injury

  This study is testing whether online therapy for insomnia or mindfulness techniques can help veterans with brain injuries sleep better and feel less depressed.

  Recruiting at 5 sites Johns Hopkins University · Eglin Air Force Base, Florida and 4 other locations · NCT05663034

• Intermittent hypoxia training for mild cognitive impairment

  This trial will test whether intermittent hypoxia training can improve thinking and memory in people aged 55–79 with mild cognitive impairment.

  Recruiting University of North Texas Health Science Center · Fort Worth, Texas · NCT05495087

• Investigating cognitive function in psychosis patients and cannabis users

  This study is testing how taking a break from cannabis for 28 days affects thinking skills and brain activity in people with psychosis and those who use cannabis but don’t have mental health issues.

  Recruiting Douglas Mental Health University Institute · Montreal, Quebec · NCT05445180

• Testing a drug to reduce stress effects on memory in Alzheimer's patients

  This study is testing if a new drug can help reduce the negative effects of stress on memory for people at risk of Alzheimer's disease.

  Recruiting Phase 2 Johns Hopkins University · Baltimore, Maryland · NCT04601038

• Investigating how aging and stress affect memory and navigation

  This study is testing how stress affects memory and navigation in older adults aged 65-80 to see if it leads to differences in cognitive decline.

  Recruiting Georgia Institute of Technology · Atlanta, Georgia · NCT03896529

• Identifying factors affecting memory impairment progression

  This study is trying to find out what factors affect how memory loss gets worse in people with Alzheimer's and related disorders by tracking their daily living skills and cognitive function over three years.

  Recruiting Hospices Civils de Lyon · Caluire-et-Cuire and 1 other locations · NCT02302482

NIH-funded research (13)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Understanding memory problems in temporal lobe epilepsy to help people with epilepsy

  A researcher at UCLA is exploring why memory worsens in temporal lobe epilepsy and how we might protect or restore memory for patients.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-11369875

• Why low-oxygen episodes in very premature babies can cause memory problems

  This work explores whether a brief low-oxygen event around birth changes how hippocampus cells mature and leads to lasting learning and memory problems in babies born very early.

  NIH research Oregon Health & Science University · Portland, United States · NIH-11166447

• Memory problems and seeing things in Parkinson's disease

  This project looks at whether changes in the hippocampus explain memory loss and visual hallucinations in people with Parkinson's disease by following them over time with tests and brain scans.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11135442

• Improving memory function in people with Parkinson's disease

  This study is all about helping people with Parkinson's disease who are having trouble with memory and daily tasks by teaching them practical tips they can use in their everyday lives to feel more confident and improve their quality of life.

  NIH research Washington University · Saint Louis, United States · NIH-11128930

• Investigating how smell loss relates to memory problems in Alzheimer's disease

  This study is looking at how problems with smell might be linked to memory issues in people with Alzheimer's disease, and it’s for anyone interested in understanding how these changes happen as we age, with the hope of finding better ways to spot Alzheimer's early.

  NIH research Pennsylvania State Univ Hershey Med Ctr · Hershey, United States · NIH-11079665

• Understanding how low oxygen affects memory in preterm infants

  This study looks at how low oxygen levels can affect memory and brain development in preterm babies who have had serious breathing problems, using a mouse model to help understand the long-term impacts on learning and memory.

  NIH research Oregon Health & Science University · Portland, United States · NIH-10939062

• Investigating how sleep affects memory in older adults at risk for Alzheimer's disease

  This study is looking at how sleep affects memory in older adults who might be at risk for Alzheimer's disease, and it aims to find out how blood vessel health impacts both sleep and memory, so we can better understand how to help people with these issues.

  NIH research University of California-Irvine · Irvine, United States · NIH-10903039

• Investigating the link between memory problems and hallucinations in Parkinson's Disease.

  This study is looking at how memory problems and seeing things that aren't there are related in people with Parkinson's Disease, and it hopes to find out if issues in a specific part of the brain are causing both of these challenges, which could lead to better care for patients.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-10891564

• Investigating postoperative delirium and memory issues using aged nonhuman primates

  This study is looking at how surgery-related confusion, known as postoperative delirium, might be linked to Alzheimer's disease by observing older monkeys and how they react to certain anesthetics, which could help us understand these issues better in people.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-10891346

• Improving memory function in people with Parkinson's disease-related cognitive decline

  This study is all about helping people with Parkinson's disease who are having trouble remembering daily tasks by teaching them new strategies to manage their activities better, so they can enjoy life more and possibly slow down memory issues.

  NIH research Washington University · Saint Louis, United States · NIH-10886048

• Understanding memory problems in temporal lobe epilepsy

  This study is looking at how changes in brain cells might affect memory in people with temporal lobe epilepsy, using mice to help find ways to improve memory for those who have this condition.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-10876402

• Investigating how high fibrinogen levels affect brain function and memory after traumatic brain injury.

  This study is looking at how high levels of a protein called fibrinogen in the blood might affect memory and thinking skills in people with Alzheimer's and similar conditions, especially after a brain injury, to find ways to help improve brain health.

  NIH research University of South Florida · Tampa, United States · NIH-10855710

• Improving memory in older adults by enhancing brain protein recycling

  This study is looking at how boosting a part of the brain that helps recycle proteins might improve memory problems that come with aging, and it's aimed at older adults who want to enhance their memory and reduce the risk of Alzheimer's disease.

  NIH research Purdue University · West Lafayette, United States · NIH-10811380

Related topics

Quick answers

How many Memory Impairment clinical trials are recruiting right now?

15, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 7 countries. The most sites are in United States (10 trials), Canada (2 trials), Norway (1 trial), France (1 trial), United Kingdom (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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