Investigating how sleep affects memory in older adults at risk for Alzheimer's disease
Cerebrovascular and neurophysiological mechanisms of sleep-dependent memory impairment in older adults at risk for Alzheimer's disease
This study is looking at how sleep affects memory in older adults who might be at risk for Alzheimer's disease, and it aims to find out how blood vessel health impacts both sleep and memory, so we can better understand how to help people with these issues.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California-Irvine NIH-funded |
| Lab location | 1 site (Irvine, United States) |
| Project ID | NIH-10903039 on NIH RePORTER |
What this research studies
This research explores the relationship between sleep and memory impairment in older adults who are at risk for Alzheimer's disease. It focuses on understanding how cerebrovascular health, particularly small vessel disease, impacts sleep and memory functions. Participants will undergo various assessments, including MRI scans and wrist-worn devices to monitor sleep patterns, to identify key factors that contribute to memory deficits. The goal is to uncover mechanisms that link sleep quality to cognitive changes associated with Alzheimer's disease.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults aged 65 and above who are experiencing memory issues or are at risk for Alzheimer's disease.
Not a fit: Patients who are younger than 65 or those without any cognitive impairment or risk factors for Alzheimer's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for enhancing sleep and memory in older adults, potentially delaying the onset of Alzheimer's disease.
How similar studies have performed: Previous research has shown promising results in understanding the links between sleep quality and cognitive decline, indicating that this approach has potential for success.
Where this research is happening
Irvine, United States
- University of California-Irvine — Irvine, United States (Active)
Researchers
- Principal investigator: Berisha, Destiny — University of California-Irvine
- Study coordinator: Berisha, Destiny
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.