Investigating the link between memory problems and hallucinations in Parkinson's Disease.

Visual hallucinations and memory impairment in Parkinson's Disease: The role of hippocampal networks

NIH-funded research Johns Hopkins University · NIH-10891564

This study is looking at how memory problems and seeing things that aren't there are related in people with Parkinson's Disease, and it hopes to find out if issues in a specific part of the brain are causing both of these challenges, which could lead to better care for patients.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionJohns Hopkins University NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-10891564 on NIH RePORTER

What this research studies

This research focuses on understanding how memory impairment and visual hallucinations are connected in patients with Parkinson's Disease (PD). By examining the role of hippocampal networks, the study aims to identify whether dysfunction in this brain region contributes to both cognitive decline and hallucinations. Patients will undergo detailed neuropsychological assessments and brain imaging to track changes over time. The findings could help clarify the mechanisms behind these symptoms and improve patient care.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with Parkinson's Disease who are experiencing memory impairment or visual hallucinations.

Not a fit: Patients with Parkinson's Disease who do not exhibit cognitive impairment or hallucinations may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better treatment strategies for managing cognitive and psychiatric symptoms in Parkinson's Disease.

How similar studies have performed: Previous research has shown that understanding hippocampal function can provide insights into cognitive and psychiatric symptoms in various disorders, suggesting potential for success in this area.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.