Improving memory function in people with Parkinson's disease-related cognitive decline

Prospective memory impairment in Parkinson disease-related cognitive decline: Intervention and mechanisms

NIH-funded research Washington University · NIH-10886048

This study is all about helping people with Parkinson's disease who are having trouble remembering daily tasks by teaching them new strategies to manage their activities better, so they can enjoy life more and possibly slow down memory issues.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWashington University NIH-funded
Lab location1 site (Saint Louis, United States)
Project IDNIH-10886048 on NIH RePORTER

What this research studies

This research focuses on helping individuals with Parkinson's disease who are experiencing cognitive decline, particularly in their ability to remember to perform tasks. The approach involves teaching patients specific strategies to manage their daily activities despite memory challenges, rather than relying on traditional repetitive practice methods. By using strategy training, the goal is to enhance daily functioning and potentially delay the progression of cognitive impairment associated with Parkinson's disease dementia. This innovative method aims to provide practical tools that patients can apply in their everyday lives.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with Parkinson's disease who are experiencing cognitive decline.

Not a fit: Patients who do not have Parkinson's disease or those with advanced dementia may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could help patients maintain their independence and improve their quality of life by enhancing their memory and daily functioning.

How similar studies have performed: While strategy training has been effective in cognitive rehabilitation for brain injury and stroke, its application to Parkinson's disease dementia is a novel approach that has not been extensively tested.

Where this research is happening

Saint Louis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired brain injuryAlzheimer's disease and related dementiaAlzheimer's disease and related disordersAlzheimer's disease or a related dementiaAlzheimer's disease or a related disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.