NIH-funded research R01 grant

Asthma and walking in older adults: brain signals, medicine use, and control

Official title: The influence of asthma on walking in older adults: brain predictors, medication adherence and asthma control

Funded at Albert Einstein College of Medicine · NIH-11382135 · Data updated 2026-11-12

This grant studies how asthma affects how older adults walk, looking at brain factors and how well they take their inhalers to understand mobility and health.

More Asthma research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionAlbert Einstein College of Medicine
NIH-funded
Lab location1 site (Bronx, United States)
Project startAugust 15, 2024
Project endMay 31, 2029
Funding year2026
Award (this year)$699,585
NIH project number5R01HL169316-03
Project IDNIH-11382135 on NIH RePORTER

Who could benefit from this research

Could help

Older adults with asthma who are able to participate in walking tests and neuroimaging assessments.

Less likely to help

Individuals without asthma or those unable to participate in walking or imaging procedures are less likely to benefit.

What this research studies

This project will explore how asthma may influence walking in older adults by examining brain structure and function, along with how well medications are taken and how well asthma is controlled. Using a dual-task walking test, researchers will measure gait performance while the brain’s activity and structure are assessed with functional near-infrared spectroscopy and MRI-based metrics. The study will focus on modifiable factors that could be targeted with behavioral and medical interventions to improve mobility and overall health. The approach combines neurological measurements with behavioral data to uncover mechanisms linking asthma to mobility impairments in older individuals.

Why it matters

Potential benefit: If successful, findings could lead to interventions that improve walking ability and brain health in older adults with asthma, potentially reducing mobility-related health risks.

How similar studies have gone: Previous research suggests links between airway disease and mobility, but this project aims to identify specific brain and behavioral mechanisms, which is relatively novel.

Where this research is happening

  • Albert Einstein College of Medicine
    Bronx, United States
    Active

Researchers

  • Principal investigator: Holtzer, Roee — Albert Einstein College of Medicine
  • Study coordinator: Holtzer, Roee

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.