NIH-funded research Sbir 1 grant

Reducing High Blood Pressure in Men in Manual Jobs with a Mobile Stress and Medication Adherence Program

Official title: Reducing Hypertension Among Men in Manual and Trade Labor: A Mobile Stress Management and Medication Adherence Intervention

Funded at Isa Associates, INC. · NIH-11408185 · Data updated 2026-11-12

A mobile stress-management and medication adherence program aims to help men in manual and trade jobs lower their blood pressure and stay on their prescribed treatment.

More Hypertension research and trials

Quick facts

Grant typeSbir 1 grant
Study typeNIH-funded research
Funding institutionIsa Associates, INC.
NIH-funded
Lab location1 site (Arlington, UNITED STATES)
Project startAugust 1, 2026
Project endApril 30, 2027
Funding year2026
Award (this year)$305,471
NIH project number1R43HL186938-01
Project IDNIH-11408185 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are men employed in manual or trade labor with high-stress work conditions and a diagnosis of hypertension or on hypertension medication.

Less likely to help

Patients not on hypertension care or not willing to use mobile health tools may see limited benefit.

What this research studies

Men working in manual and trade careers face demanding, low-control environments that raise stress and BP. This grant tests a practical, phone-based program that combines stress management with reminders and support to take blood pressure medicine. The approach is designed to fit into tight work schedules and shift patterns, using daily prompts and easy access to coping strategies. If successful, the program could become a scalable way to reduce cardiovascular risk for a large, underserved workforce.

Why it matters

Potential benefit: If effective, the program could help lower blood pressure and reduce heart disease risk for men in demanding jobs, improving overall health and productivity.

How similar studies have gone: Previous stress-management and medication adherence efforts show promise in similar populations, but this specific occupational group has been understudied.

Where this research is happening

  • Isa Associates, INC.
    Arlington, United States
    Active

Researchers

  • Principal investigator: Leaf, Samantha L. — Isa Associates, INC.
  • Study coordinator: Leaf, Samantha L.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.